Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00451828 · ClinicalTrials.gov registry record · Phase 4
Cholesterol and Pharmacogenetic Study
A Phase 4 study of Cardiovascular Disease and Hypercholesterolemia, sponsored by UCSF Benioff Children's Hospital Oakland.
- Completed
- Registry status
- Phase 4
- Development phase
- 1,000
- Enrollment target
- 1
- Study location
NCT00451828: Completed Phase 4 study of Cardiovascular Disease and Hypercholesterolemia, sponsored by UCSF Benioff Children's Hospital Oakland.
NCT00451828 is a Phase 4 study of Cardiovascular Disease and Hypercholesterolemia that has completed, run by UCSF Benioff Children's Hospital Oakland. The registered enrollment target is 1,000 participants, below the 2,690-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00451828, a Phase 4 study of Cardiovascular Disease and Hypercholesterolemia, has completed, sponsored by UCSF Benioff Children's Hospital Oakland.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective of the CAP study was to determine genetic influences on efficacy of simvastatin treatment with regard to LDL cholesterol reduction and changes in other markers of cardiovascular disease risk.
Conditions Studied
Interventions
- DRUG Simvastatin
Study Locations (1)
California
- San Francisco General Hospital - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2002-03 |
| Phase | Phase 4 |
What the finished NCT00451828 record still lists
NCT00451828 is an interventional study that assigns participants to a tested intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, below the 2,690-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (63% lower).
The record links to 4 conditions, with Cardiovascular Disease appearing as the primary indexed condition, and to 1 intervention - of which Simvastatin is the first listed.
NCT00451828 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00451828 about?
NCT00451828 is a clinical study titled "Cholesterol and Pharmacogenetic Study". The overall objective of the CAP study was to determine genetic influences on efficacy of simvastatin treatment with regard to LDL cholesterol reduction and changes in other markers of cardiovascular disease risk.
What is the current status of trial NCT00451828?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 1,000 participants. The study started on 2002-03.
What conditions does trial NCT00451828 study?
This clinical trial studies the following conditions: Cardiovascular Disease, Hypercholesterolemia, Hyperlipidemia, Coronary Heart Disease.
What interventions are being tested in trial NCT00451828?
The interventions under investigation include: Simvastatin (DRUG).
Who is sponsoring clinical trial NCT00451828?
This trial is sponsored by UCSF Benioff Children's Hospital Oakland, which has 52 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00451828 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00451828's enrollment target sits among peer trials
1,000 30th of 137 higher than 108 of 137 other Cardiovascular Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
RECRUITING · Phase 4
-
Randomized Trial of SGLT2i in Heart Transplant Recipients
RECRUITING · Phase 4
-
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
ACTIVE NOT RECRUITING · Phase 4
-
MIcrovascular dysfuNction In Moderate-severe Psoriasis
COMPLETED · Phase 4
-
Phosphate Lowering in CKD Trial
COMPLETED · Phase 4
-
Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)
COMPLETED · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00018044 · 1,000 participants
Study of Mycobacterial Infections
- NCT01036581 · 1,000 participants · NA
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
- NCT01192048 · 1,000 participants
Genetics of Congenital Heart Disease
- NCT01553214 · 1,000 participants · Phase 4
Improving White Blood Cell Collection From Healthy Donors
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia