Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hypercholesterolemia: full-pipeline trial registry
5 of 63 indexed Hypercholesterolemia trials are currently recruiting.
Corpus placement: #222 of 28,707 conditions by registered trial count.
63 US clinical trials · 5 currently recruiting · #222 of 28,707 conditions by registered trial count
Hypercholesterolemia: 63 US clinical trials tracked, 5 recruiting.
Hypercholesterolemia is the subject of 63 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis, running 4 of these trials.
Enrollment posture brief
Registry condition hypercholesterolemia
OPEN 5 | RECR 8% | LATE 26 | EARLY 18 | RANK #222 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Sinusitis (8% recruiting · 13 trials)
Hypercholesterolemia lists 5 open slots (8% of 63 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypercholesterolemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Hypercholesterolemia is recruiting below its size-band peers.
5 of 63 indexed trials (7.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Hypercholesterolemia trials is spread across many organizations.
Novartis accounts for 4 of 63 trials (6.3%). 41 distinct sponsors appear on at least one study for this condition label.
-
Typical Hypercholesterolemia enrolment sits around 143 participants.
Median target enrolment is 143 among the 63 trials that report a genuine target (sentinel values excluded). 24 of those (38.1%) plan for fewer than 100 participants.
-
Hypercholesterolemia research is mostly interventional.
56 interventional and 7 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
63 total, page 2 of 2
The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia
Aegerion Pharmaceuticals
NCT00405067
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
The Cleveland Clinic
NCT01817491
Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)
Regeneron Pharmaceuticals
NCT01576484
Effect of Diabetes Mellitus on Cholesterol Metabolism
Medical College of Wisconsin
NCT00879710
Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults
University of Missouri-Columbia
NCT01227330
Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells
Emory University
NCT00166036
Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol
Bronx VA Medical Center
NCT00762164
Open-Label Extension to Evaluate the Longer Term Efficacy and Safety of LIB003
LIB Therapeutics
NCT03847974
Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00046267
Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
Beth Israel Deaconess Medical Center
NCT01702987
Using Nudges to Implement Comparative Effectiveness
NYU Langone Health
NCT01575171
A Study of LY3015014 in Healthy Participants With High Cholesterol
Eli Lilly and Company
NCT01671085
Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans
USDA, Western Human Nutrition Research Center
NCT02011789
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 10 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypercholesterolemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypercholesterolemia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypercholesterolemia page
63 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Hypercholesterolemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Novartis sponsors the most Hypercholesterolemia trials on record, review their full trial history before evaluating a specific study. See Novartis's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypercholesterolemia condition card totals 63 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.