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NCT00879710 · ClinicalTrials.gov registry record · NA

Effect of Diabetes Mellitus on Cholesterol Metabolism

A NA study of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus, sponsored by Medical College of Wisconsin.

Completed
Registry status
NA
Development phase
57
Enrollment target
1
Study location

NCT00879710 is a NA study of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus that has completed, run by Medical College of Wisconsin. The registered enrollment target is 57 participants, below the 2,748-participant average among 122 other Type 2 Diabetes Mellitus trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00879710, a NA study of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus, has completed, sponsored by Medical College of Wisconsin.

COMPLETED
Registry status
NA
Development phase
57 participants
Enrollment target
1
Study location

Study Summary

HMG CoA reductase inhibitors (statins) are commonly used to treat high cholesterol (HC) in both type 1 and type 2 diabetes mellitus (DM). Several studies have shown benefits of statin among patients of type 2 DM, however, no such data is available for patients with type 1 DM. It is known from studies on cholesterol metabolism using surrogate markers that patients with type 1 DM have higher cholesterol absorption compared to normals and those with type 2 DM have higher cholesterol synthesis. Since statins inhibit synthesis, patients with type 1 DM may not have a good response and may respond better to cholesterol absorption inhibitors. The purpose of this study is to determine the cholesterol lowering effects of cholesterol absorption inhibitors and cholesterol synthesis inhibitors in subjects with type 1 and type 2 diabetes mellitus.

Interventions

  • DRUG simvastatin or ezetimibe

Study Locations (1)

Wisconsin

  • Medical College of Wisconsin /Froedtert Hospital - Milwaukee

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2008-08
Est. Completion 2013-07
Phase NA

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT00879710

The ClinicalTrials.gov registry entry for NCT00879710 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,748-participant average among 122 other Type 2 Diabetes Mellitus trials with a reported enrollment target (98% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Type 2 Diabetes Mellitus appearing as the primary indexed condition, and to 1 intervention - of which simvastatin or ezetimibe is the first listed.

NCT00879710 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT00879710 about?

NCT00879710 is a clinical study titled "Effect of Diabetes Mellitus on Cholesterol Metabolism". HMG CoA reductase inhibitors (statins) are commonly used to treat high cholesterol (HC) in both type 1 and type 2 diabetes mellitus (DM). Several studies have shown benefits of statin among patients of type 2 DM, however, no such data is available for patients with type 1 DM. It is known from studi...

What is the current status of trial NCT00879710?

This trial is currently completed. It is a NA study. The enrollment target is 57 participants. The study started on 2008-08. Estimated completion is 2013-07.

What conditions does trial NCT00879710 study?

This clinical trial studies the following conditions: Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus, Hypercholesterolemia.

What interventions are being tested in trial NCT00879710?

The interventions under investigation include: simvastatin or ezetimibe (DRUG).

Who is sponsoring clinical trial NCT00879710?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00879710 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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