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NCT01702987 · ClinicalTrials.gov registry record · NA
Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
A NA study of Hypercholesterolemia and Myopathy, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT01702987: Completed NA study of Hypercholesterolemia and Myopathy, sponsored by Beth Israel Deaconess Medical Center.
NCT01702987 is a NA study of Hypercholesterolemia and Myopathy that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 22 participants, below the 816-participant average among 62 other Hypercholesterolemia trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01702987, a NA study of Hypercholesterolemia and Myopathy, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
It is our primary hypothesis that statin drugs impair skeletal muscle mitochondrial function and that ubiquinol (the reduced active form of CoQ10) supplementation will block impairment of PCr recovery kinetics in patients using statins. The investigators propose a pilot study to extend our research to examine PCr recovery kinetics in 20 statin users randomized in a parallel arm study to either ubiquinol or placebo over 4 weeks.
Primary Outcome
Percentage change in phosphocreatine recovery from baseline to month as measured by 31PMRS is the primary outcome measure is a representative of mitochondrial oxidative capacity
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT placebo
- DIETARY_SUPPLEMENT ubiquinol
- DRUG statin
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2012-10 |
| Est. Completion | 2013-10 |
| Phase | NA |
What the finished NCT01702987 record still lists
NCT01702987 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 816-participant average among 62 other Hypercholesterolemia trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Hypercholesterolemia appearing as the primary indexed condition, and to 3 interventions - of which placebo is the first listed.
NCT01702987 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01702987 about?
NCT01702987 is a clinical study titled "Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS". It is our primary hypothesis that statin drugs impair skeletal muscle mitochondrial function and that ubiquinol (the reduced active form of CoQ10) supplementation will block impairment of PCr recovery kinetics in patients using statins. The investigators propose a pilot study to extend our research ...
What is the current status of trial NCT01702987?
This trial is currently completed. It is a NA study. The enrollment target is 22 participants. The study started on 2012-10. Estimated completion is 2013-10.
What conditions does trial NCT01702987 study?
This clinical trial studies the following conditions: Hypercholesterolemia, Myopathy, HMG COA Reductase Inhibitor Adverse Reaction.
What interventions are being tested in trial NCT01702987?
The interventions under investigation include: placebo (DIETARY_SUPPLEMENT), ubiquinol (DIETARY_SUPPLEMENT), statin (DRUG).
Who is sponsoring clinical trial NCT01702987?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01702987 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01702987's enrollment target sits among peer trials
22 59th of 62 higher than 4 of 62 other Hypercholesterolemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypercholesterolemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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