Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV

NCT05904470 · View on ClinicalTrials.gov ↗

Study Summary

This is an open-label trial to evaluate safety and efficacy of treatment with BEM + RZR in subjects with chronic HCV infection.

Interventions

  • DRUG Bemnifosbuvir
  • DRUG Ruzasvir

Study Locations (20)

São Paulo

  • Atea Study Site — Botucatu
  • Atea Study Site — Ijuí
  • Atea Study Site — São José do Rio Preto
  • Atea Study Site — São Paulo
  • Atea Study Site — São Paulo
  • Atea Study Site — Sorocaba

Rio Grande do Sul

  • Atea Study Site — Porto Alegre
  • Atea Study Site — Porto Alegre

Gujarat

  • Atea Study Site — Rajkot
  • Atea Study Site — Surat

Texas

  • Atea Study Site — San Antonio

Amazonas

  • Atea Study Site — Manaus

Estado de Bahia

  • Atea Study Site — Salvador

Federal District

  • Atea Study Site — Brasília

Rio Do Janeiro

  • Atea Study Site — Rio de Janeiro

Trial Details

FieldValue
Enrollment Target 275 participants
Start Date 2023-05-30
Est. Completion 2025-01-28
Phase Phase 2

Sponsor

Atea Pharmaceuticals

36 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05904470

The ClinicalTrials.gov registry entry for NCT05904470 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 275 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Atea Pharmaceuticals, which has 36 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Hepatitis C appearing as the primary indexed condition, and to 2 interventions — of which Bemnifosbuvir is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05904470 reports 20 study locations spanning 13 distinct geographic areas — top geographies include São Paulo, Rio Grande do Sul, Gujarat. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05904470 about?

NCT05904470 is a clinical study titled "A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV". This is an open-label trial to evaluate safety and efficacy of treatment with BEM + RZR in subjects with chronic HCV infection.

What is the current status of trial NCT05904470?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 275 participants. The study started on 2023-05-30. Estimated completion is 2025-01-28.

What conditions does trial NCT05904470 study?

This clinical trial studies the following conditions: Hepatitis C, Hepatitis C, Chronic, HCV, Chronic Hepatitis C Virus, Hepatic Cirrhosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05904470?

The interventions under investigation include: Bemnifosbuvir (DRUG), Ruzasvir (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05904470?

This trial is sponsored by Atea Pharmaceuticals, which has 36 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05904470 being conducted?

This trial has 20 study locations across Texas, Amazonas, Estado de Bahia, Federal District, Rio Do Janeiro. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial