Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01675427 · ClinicalTrials.gov registry record · Phase 4

A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C

A Phase 4 study of Hepatitis C, Chronic, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 4
Development phase
4,766
Enrollment target
20
Study locations

NCT01675427: Completed Phase 4 study of Hepatitis C, Chronic, sponsored by Hoffmann-La Roche.

NCT01675427 is a Phase 4 study of Hepatitis C, Chronic that has completed, run by Hoffmann-La Roche. The registered enrollment target is 4,766 participants, above the 193-participant average among 26 other Hepatitis C, Chronic trials with a reported enrollment target (2369% higher). The trial reports 20 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01675427, a Phase 4 study of Hepatitis C, Chronic, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 4
Development phase
4,766 participants
Enrollment target
20
Study locations

Study Summary

This multicenter study will evaluate the correlation of interleukin 28B (IL28B) genotypes with disease characteristics and demographics in treatment-naïve and treatment-experienced chronic hepatitis C patients, including patients with HIV co-infection. There will be a single study visit for testing.

Primary Outcome

Participants underwent blood sampling at the Study Visit to determine IL28B genotype. HCV RNA genotype (Genotype 1 \[G1\], Genotype 2 \[G2\], Genotype 3 \[G3\], Genotype 4 \[G4\], and all other genotypes \[Other\]) and cirrhosis status ('Cirrhosis/transition to cirrhosis' or 'No cirrhosis') were obtained from medical records. Cirrhosis status was based upon previous biopsy or noninvasive assessment captured prior to treatment, if applicable.

Conditions Studied

Hepatitis C, Chronic

Interventions

  • OTHER Interleukin 28B testing

Study Locations (20)

Other

  • - Buenos Aires
  • - Mar del Plata
  • - Antwerp
  • - Bruges
  • - Brussels
  • - Brussels
  • - Brussels
  • - Brussels
  • - Brussels
  • - Brussels
  • - Edegem
  • - Genk
  • - Ghent
  • - Hasselt
  • - Heusy
  • - Kortrijk
  • - Leuven
  • - Liège
  • - Ostend

Virginia

  • - Alexandria

Trial Details

FieldValue
Enrollment Target 4,766 participants
Start Date 2011-08
Est. Completion 2013-10
Phase Phase 4
Hoffmann-La Roche

909 total trials

What the finished NCT01675427 record still lists

NCT01675427 is an interventional study that assigns participants to a tested intervention. Its 4,766 participants enrollment target places it among the larger protocols in the corpus, above the 193-participant average among 26 other Hepatitis C, Chronic trials with a reported enrollment target (2369% higher).

The record links to 1 condition, with Hepatitis C, Chronic appearing as the primary indexed condition, and to 1 intervention - of which Interleukin 28B testing is the first listed.

NCT01675427 names 20 study sites across 2 states, led by Other, Virginia.

Frequently Asked Questions

What is clinical trial NCT01675427 about?

NCT01675427 is a clinical study titled "A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C". This multicenter study will evaluate the correlation of interleukin 28B (IL28B) genotypes with disease characteristics and demographics in treatment-naïve and treatment-experienced chronic hepatitis C patients, including patients with HIV co-infection. There will be a single study visit for testing.

What is the current status of trial NCT01675427?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 4,766 participants. The study started on 2011-08. Estimated completion is 2013-10.

What conditions does trial NCT01675427 study?

This clinical trial studies the following conditions: Hepatitis C, Chronic.

What interventions are being tested in trial NCT01675427?

The interventions under investigation include: Interleukin 28B testing (OTHER).

Who is sponsoring clinical trial NCT01675427?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01675427 being conducted?

This trial has 20 study locations across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Hepatitis C, Chronic

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01675427's enrollment target sits among peer trials

4,766 1st of 26 higher than 26 of 26 other Hepatitis C, Chronic trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hepatitis C, Chronic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01719055 · 4,800 participants

    RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

  • NCT05485675 · 4,800 participants · NA

    Stand & Move at Work II: Effectiveness and Implementation of a Worksite Wellness Program

  • NCT06307652 · 4,800 participants · Phase 3

    Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

  • NCT04371900 · 4,700 participants · NA

    Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Related registry views

Source: ClinicalTrials.gov NCT01675427, the US trial registry maintained by the National Library of Medicine. NCT01675427 (large enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.