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NCT02772068 · ClinicalTrials.gov registry record · Early Phase 1
Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
A Early Phase 1 study of Heart Failure, Congestive, sponsored by Benjamin Levine.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 26
- Enrollment target
- 1
- Study location
NCT02772068 is a Early Phase 1 study of Heart Failure, Congestive that has completed, run by Benjamin Levine. The registered enrollment target is 26 participants, below the 641-participant average among 33 other Heart Failure, Congestive trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02772068, a Early Phase 1 study of Heart Failure, Congestive, has completed, sponsored by Benjamin Levine.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 26 participants
- Enrollment target
- 1
- Study location
Study Summary
Heart failure with preserved ejection fraction or HFpEF, represents nearly 50% of all heart failure cases and is particularly common in the elderly. The disease has no current treatment options. Symptoms typically occur during exertion or exercise and is likely the result of increased cardiac and pulmonary congestion as a result of impaired diastolic function. Istaroxime is a novel activator of SERCA2a, an important regulator of calcium uptake within the myocyte. We will test the hypothesis that Istaroxime will improve diastolic function during exercise in HFpEF patients which in turn will reduce cardiac and pulmonary congestion.
Conditions Studied
Interventions
- OTHER Exercise
- DRUG Istaroxime
Study Locations (1)
Texas
- The Institute for Exercise and Environmental Medicine - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2015-09-15 |
| Est. Completion | 2018-12-01 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02772068
The ClinicalTrials.gov registry entry for NCT02772068 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 641-participant average among 33 other Heart Failure, Congestive trials with a reported enrollment target (96% lower). The listed sponsor is Benjamin Levine, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Heart Failure, Congestive appearing as the primary indexed condition, and to 2 interventions - of which Exercise is the first listed.
NCT02772068 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT02772068 about?
NCT02772068 is a clinical study titled "Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a". Heart failure with preserved ejection fraction or HFpEF, represents nearly 50% of all heart failure cases and is particularly common in the elderly. The disease has no current treatment options. Symptoms typically occur during exertion or exercise and is likely the result of increased cardiac and pu...
What is the current status of trial NCT02772068?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 26 participants. The study started on 2015-09-15. Estimated completion is 2018-12-01.
What conditions does trial NCT02772068 study?
This clinical trial studies the following conditions: Heart Failure, Congestive.
What interventions are being tested in trial NCT02772068?
The interventions under investigation include: Exercise (OTHER), Istaroxime (DRUG).
Who is sponsoring clinical trial NCT02772068?
This trial is sponsored by Benjamin Levine, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02772068 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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