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NCT00233480 · ClinicalTrials.gov registry record · Phase 4
Statin Therapy in Heart Failure: Potential Mechanisms of Benefit
A Phase 4 study of Heart Failure, Congestive, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- Phase 4
- Development phase
- 27
- Enrollment target
- 1
- Study location
NCT00233480: Completed Phase 4 study of Heart Failure, Congestive, sponsored by University of California, Los Angeles.
NCT00233480 is a Phase 4 study of Heart Failure, Congestive that has completed, run by University of California, Los Angeles. The registered enrollment target is 27 participants, below the 674-participant average among 39 other Heart Failure, Congestive trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00233480, a Phase 4 study of Heart Failure, Congestive, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of the investigators' study is to further understand the potentially beneficial effects of statin therapy in patients with heart failure. It is hypothesized that statins will 1) increase the heart's pumping ability 2) improve functioning of the sympathetic nervous system and 3) decrease immune activation in heart failure.
Primary Outcome
Left ventricular ejection fraction was assessed by transthoracic echocardiography according to Simpson's rule (biplane method of disks).
Conditions Studied
Interventions
- DRUG placebo
- DRUG atorvastatin
Study Locations (1)
California
- Ahmanson-UCLA Cardiomyopathy Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2005-08 |
| Est. Completion | 2009-02 |
| Phase | Phase 4 |
What the finished NCT00233480 record still lists
NCT00233480 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 674-participant average among 39 other Heart Failure, Congestive trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Heart Failure, Congestive appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT00233480 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00233480 about?
NCT00233480 is a clinical study titled "Statin Therapy in Heart Failure: Potential Mechanisms of Benefit". The goal of the investigators' study is to further understand the potentially beneficial effects of statin therapy in patients with heart failure. It is hypothesized that statins will 1) increase the heart's pumping ability 2) improve functioning of the sympathetic nervous system and 3) decrease imm...
What is the current status of trial NCT00233480?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 27 participants. The study started on 2005-08. Estimated completion is 2009-02.
What conditions does trial NCT00233480 study?
This clinical trial studies the following conditions: Heart Failure, Congestive.
What interventions are being tested in trial NCT00233480?
The interventions under investigation include: placebo (DRUG), atorvastatin (DRUG).
Who is sponsoring clinical trial NCT00233480?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00233480 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure, Congestive
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00233480's enrollment target sits among peer trials
27 35th of 39 higher than 5 of 39 other Heart Failure, Congestive trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure, Congestive trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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