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NCT00733590 · ClinicalTrials.gov registry record

Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention

A clinical trial of Heart Failure, Congestive and Cardiomyopathies, sponsored by Johns Hopkins University.

Recruiting
Registry status
1,500
Enrollment target
4
Study locations

NCT00733590 is a study of Heart Failure, Congestive and Cardiomyopathies that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 1,500 participants, above the 596-participant average among 33 other Heart Failure, Congestive trials with a reported enrollment target (152% higher). The trial reports 4 study locations across 3 states.

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The verdict

NCT00733590, a study of Heart Failure, Congestive and Cardiomyopathies, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
1,500 participants
Enrollment target
4
Study locations

Study Summary

The overall hypothesis of this study is that subtle interactions between structural (substrate) and functional (trigger) abnormalities of the heart, some of which are genetically-determined, can be used to identify patients at high risk of sudden cardiac death (SCD). Such information may be used to better define patients most likely to benefit from replacement of an internal defibrillator (ICD). The prospective, observational study to enroll, categorize and follow patients who receive an ICD pulse generator replacement for primary prevention of SCD (PROSe-ICD) was established to : 1. to gain a better understanding of the biological mechanisms that predispose to SCD 2. to develop readily determined clinical, electrocardiographic, genetic and blood protein markers identify patients with an increased risk of dying suddenly

Study Locations (4)

Maryland

  • University of Maryland Medical Center - Baltimore
  • Johns Hopkins University School of Medicine - Baltimore

District of Columbia

  • Washington Hospital Center - Washington D.C.

Virginia

  • Virginia Commonwealth University School of Medicine - Richmond

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2003-06
Est. Completion 2029-03

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT00733590

The ClinicalTrials.gov registry entry for NCT00733590 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 596-participant average among 33 other Heart Failure, Congestive trials with a reported enrollment target (152% higher). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Heart Failure, Congestive appearing as the primary indexed condition, and to 0 interventions.

NCT00733590 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Maryland, District of Columbia, Virginia.

Frequently Asked Questions

What is clinical trial NCT00733590 about?

NCT00733590 is a clinical study titled "Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention". The overall hypothesis of this study is that subtle interactions between structural (substrate) and functional (trigger) abnormalities of the heart, some of which are genetically-determined, can be used to identify patients at high risk of sudden cardiac death (SCD). Such information may be used to ...

What is the current status of trial NCT00733590?

This trial is currently recruiting. The enrollment target is 1,500 participants. The study started on 2003-06. Estimated completion is 2029-03.

What conditions does trial NCT00733590 study?

This clinical trial studies the following conditions: Heart Failure, Congestive, Cardiomyopathies, Arrhythmia, Death, Sudden, Cardiac.

Who is sponsoring clinical trial NCT00733590?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00733590 being conducted?

This trial has 4 study locations across District of Columbia, Maryland, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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