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NCT02805257 · ClinicalTrials.gov registry record · Phase 2
Ahmed Glaucoma Valve Surgery With Mitomycin-C
A Phase 2 study of Glaucoma and Primary Open Angle Glaucoma, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 2
- Development phase
- 119
- Enrollment target
- 4
- Study locations
NCT02805257: Completed Phase 2 study of Glaucoma and Primary Open Angle Glaucoma, sponsored by University of California, San Francisco.
NCT02805257 is a Phase 2 study of Glaucoma and Primary Open Angle Glaucoma that has completed, run by University of California, San Francisco. The registered enrollment target is 119 participants, below the 909-participant average among 92 other Glaucoma trials with a reported enrollment target (87% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02805257, a Phase 2 study of Glaucoma and Primary Open Angle Glaucoma, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 119 participants
- Enrollment target
- 4
- Study locations
Study Summary
This study will determine the effectiveness of Mitomycin-C use in the glaucoma surgery Ahmed valve implantation. Approximately 100 patients will be enrolled, with half receiving the Mitomycin-C treatment and the other half receiving placebo treatment.
Primary Outcome
Goldmann applanation tonometry was used to measure intraocular pressure (IOP) at their one-year after surgery visit, however, for patients with irregular corneal astigmatism, corneal scarring, or corneal edema, which affect accurate measurement, pneumatonometer or Tonopen (Reichert Technologies, Depew, NY) was used. Two consecutive measurements were taken for the study eye. If the 2 measurements differ by 1 mm Hg or less, the IOP for the study eye was the average of the 2 readings. If the 2 meas
Conditions Studied
Interventions
- DRUG Mitomycin-C
- OTHER Balanced Salt Solution
- PROCEDURE Ahmed Glaucoma Valve Implant
Study Locations (4)
California
- University of California, San Francisco - San Francisco
Guangdong
- Zhongshan Ophthalmic Center - Guangzhou
Chhattisgarh
- Shri Ganesh Vinayak Eye Hospital - Raipur
Other
- Asociación para Evitar la Ceguera en México (APEC) - Mexico City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2016-06 |
| Est. Completion | 2020-03 |
| Phase | Phase 2 |
What the finished NCT02805257 record still lists
NCT02805257 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 909-participant average among 92 other Glaucoma trials with a reported enrollment target (87% lower).
The record links to 4 conditions, with Glaucoma appearing as the primary indexed condition, and to 3 interventions - of which Mitomycin-C is the first listed.
NCT02805257 reports a single indexed study location in California, Guangdong, Chhattisgarh.
Frequently Asked Questions
What is clinical trial NCT02805257 about?
NCT02805257 is a clinical study titled "Ahmed Glaucoma Valve Surgery With Mitomycin-C". This study will determine the effectiveness of Mitomycin-C use in the glaucoma surgery Ahmed valve implantation. Approximately 100 patients will be enrolled, with half receiving the Mitomycin-C treatment and the other half receiving placebo treatment.
What is the current status of trial NCT02805257?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 119 participants. The study started on 2016-06. Estimated completion is 2020-03.
What conditions does trial NCT02805257 study?
This clinical trial studies the following conditions: Glaucoma, Primary Open Angle Glaucoma, Secondary Glaucoma, Neovascular Glaucoma.
What interventions are being tested in trial NCT02805257?
The interventions under investigation include: Mitomycin-C (DRUG), Balanced Salt Solution (OTHER), Ahmed Glaucoma Valve Implant (PROCEDURE).
Who is sponsoring clinical trial NCT02805257?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02805257 being conducted?
This trial has 4 study locations across California, Guangdong, Chhattisgarh. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02805257's enrollment target sits among peer trials
119 39th of 92 higher than 53 of 92 other Glaucoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glaucoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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