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ClinicalTrials.gov 7 recruiting now official registry

Gastrointestinal Neoplasms clinical trials

7 of 13 indexed Gastrointestinal Neoplasms trials are currently recruiting.

13 US clinical trials · 7 currently recruiting

Gastrointestinal Neoplasms is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 2 of these trials.

The research picture

Gastrointestinal Neoplasms has 13 registered US clinical trials, 7 of them open to new participants right now, about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: GlaxoSmithKline
Phase 14Phase 22Phase 33

Active & Recent Trials

13 total, page 1 of 1

RECRUITING 8,000 participants

Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions

California Pacific Medical Center Research Institute

NCT01750619

RECRUITING Phase 3 800 participants

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Pfizer

NCT07222800

RECRUITING Phase 3 450 participants

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

GlaxoSmithKline

NCT07218926

RECRUITING NA 360 participants

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Cedars-Sinai Medical Center

NCT04907643

RECRUITING Phase 1 320 participants

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

GlaxoSmithKline

NCT06885034

RECRUITING Phase 1 278 participants

First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

IDRx Inc. - A GSK Company

NCT05489237

RECRUITING Phase 1 220 participants

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Janssen Research & Development

NCT06663319

ACTIVE NOT RECRUITING Phase 3 957 participants

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

AstraZeneca

NCT04592913

ACTIVE NOT RECRUITING NA 80 participants

Monopolar Current Cutting Knife vs Bipolar RFA Knife

Baylor College of Medicine

NCT04919824

ACTIVE NOT RECRUITING Phase 2 60 participants

Avatrombopag vs. Placebo for CIT in GI Malignancies

Hanny Al-Samkari, MD

NCT05772546

ACTIVE NOT RECRUITING NA 30 participants

Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei

M.D. Anderson Cancer Center

NCT01946854

COMPLETED Phase 1 25 participants

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Pharmacyclics

NCT00120939

COMPLETED Phase 2 16 participants

A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib

Exelixis

NCT00570635

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 2
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Gastrointestinal Neoplasms Trial Landscape

13 indexed Gastrointestinal Neoplasms studies · 7 recruiting (54%).

Phase mix: 3 late (III/IV) vs 6 early (I/II).

Top sponsor: GlaxoSmithKline (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Gastrointestinal Neoplasms?

PlainTrial tracks 13 US clinical trials for Gastrointestinal Neoplasms, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Gastrointestinal Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.