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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Gastrointestinal Neoplasms: early-phase trial registry

7 of 13 indexed Gastrointestinal Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 7 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Gastrointestinal Neoplasms: 13 US clinical trials tracked, 7 recruiting.

Gastrointestinal Neoplasms is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 2 of these trials.

Enrollment posture brief

Registry condition gastrointestinal-neoplasms

OPEN 7 | RECR 54% | LATE 3 | EARLY 6 | RANK #1315 | SPON 2

Nearest open-share peer: Advanced Renal Cell Carcinoma (54% recruiting · 13 trials)

ACL Injury61.5%Gastrointestinal Neoplas (th…54%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Gastrointestinal Neoplasms

Gastrointestinal Neoplasms lists 7 open slots (54% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Gastrointestinal Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Gastrointestinal Neoplasms is recruiting above its size-band peers.

    7 of 13 indexed trials (53.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Gastrointestinal Neoplasms research.

    GlaxoSmithKline accounts for 2 of 13 trials (15.4%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Gastrointestinal Neoplasms enrolment sits around 278 participants.

    Median target enrolment is 278 among the 13 trials that report a genuine target (sentinel values excluded). 5 of those (38.5%) plan for fewer than 100 participants.

  4. Gastrointestinal Neoplasms research is mostly interventional.

    12 interventional and 1 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 22Phase 33

Open and recent trials

13 total, page 1 of 1

RECRUITING 8,000 participants

Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions

California Pacific Medical Center Research Institute

NCT01750619

RECRUITING Phase 3 800 participants

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Pfizer

NCT07222800

RECRUITING Phase 3 450 participants

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

GlaxoSmithKline

NCT07218926

RECRUITING NA 360 participants

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Cedars-Sinai Medical Center

NCT04907643

RECRUITING Phase 1 320 participants

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

GlaxoSmithKline

NCT06885034

RECRUITING Phase 1 278 participants

First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

IDRx Inc. - A GSK Company

NCT05489237

RECRUITING Phase 1 220 participants

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Janssen Research & Development

NCT06663319

ACTIVE NOT RECRUITING Phase 3 957 participants

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

AstraZeneca

NCT04592913

ACTIVE NOT RECRUITING NA 80 participants

Monopolar Current Cutting Knife vs Bipolar RFA Knife

Baylor College of Medicine

NCT04919824

ACTIVE NOT RECRUITING Phase 2 60 participants

Avatrombopag vs. Placebo for CIT in GI Malignancies

Hanny Al-Samkari, MD

NCT05772546

ACTIVE NOT RECRUITING NA 30 participants

Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei

M.D. Anderson Cancer Center

NCT01946854

COMPLETED Phase 1 25 participants

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Pharmacyclics

NCT00120939

COMPLETED Phase 2 16 participants

A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib

Exelixis

NCT00570635

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 2
Phase 3 3

Named interventions

Most-linked intervention names on Gastrointestinal Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

IDRX-42 Drug
2 trials
Motexafin Gadolinium Drug
1 trials
XL820 Drug
1 trials
FLOT chemotherapy Drug
1 trials
Endoscopic Mucosal Resection Procedure
1 trials
Avatrombopag Drug
1 trials
JNJ-89402638 Drug
1 trials
Endoscopic Submucosal Dissection Procedure
1 trials

US sites by state

Facility locations filed on Gastrointestinal Neoplasms trials. A trial with sites in several states counts in each.

Texas 7 trials
Washington 5 trials
New York 5 trials
Massachusetts 5 trials
Florida 5 trials
California 5 trials
Pennsylvania 3 trials
Oregon 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Gastrointestinal Neoplasms page

13 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Gastrointestinal Neoplasms trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • GlaxoSmithKline sponsors the most Gastrointestinal Neoplasms trials on record, review their full trial history before evaluating a specific study. See GlaxoSmithKline's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Gastrointestinal Neoplasms condition card totals 13 registered trials; most-linked intervention IDRX-42; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.