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RECRUITING Phase 1

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

NCT06885034 · View on ClinicalTrials.gov ↗

Study Summary

This study will check how well a new medicine, GSK5764227, works, how safe it is and how the body handles it in participants all around the world with advanced inoperable or metastatic gastrointestinal cancer who have previously received treatment.

Conditions Studied

Interventions

  • BIOLOGICAL GSK5764227

Study Locations (20)

Other

  • GSK Investigational Site — Bonheiden
  • GSK Investigational Site — Brussels
  • GSK Investigational Site — Leuven
  • GSK Investigational Site — Roeselare
  • GSK Investigational Site — Porto Alegre
  • GSK Investigational Site — São Paulo
  • GSK Investigational Site — Teresina
  • GSK Investigational Site — Paris
  • GSK Investigational Site — Paris

California

  • GSK Investigational Site — Los Alamitos
  • GSK Investigational Site — Whittier

Texas

  • GSK Investigational Site — Houston
  • GSK Investigational Site — San Antonio

Victoria

  • GSK Investigational Site — Heidelberg
  • GSK Investigational Site — Melbourne

New York

  • GSK Investigational Site — New York

North Carolina

  • GSK Investigational Site — Durham

Washington

  • GSK Investigational Site — Wenatchee

Ontario

  • GSK Investigational Site — Toronto

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2025-06-11
Est. Completion 2028-06-23
Phase Phase 1

Sponsor

GlaxoSmithKline

558 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06885034

The ClinicalTrials.gov registry entry for NCT06885034 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Gastrointestinal Neoplasms appearing as the primary indexed condition, and to 1 intervention — of which GSK5764227 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06885034 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, California, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06885034 about?

NCT06885034 is a clinical study titled "A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed". This study will check how well a new medicine, GSK5764227, works, how safe it is and how the body handles it in participants all around the world with advanced inoperable or metastatic gastrointestinal cancer who have previously received treatment.

What is the current status of trial NCT06885034?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 320 participants. The study started on 2025-06-11. Estimated completion is 2028-06-23.

What conditions does trial NCT06885034 study?

This clinical trial studies the following conditions: Gastrointestinal Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06885034?

The interventions under investigation include: GSK5764227 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06885034?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06885034 being conducted?

This trial has 20 study locations across California, New York, North Carolina, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial