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Familial Adenomatous Polyposis clinical trials
6 of 11 indexed Familial Adenomatous Polyposis trials are currently recruiting.
11 US clinical trials · 6 currently recruiting
Familial Adenomatous Polyposis is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.
The research picture
Familial Adenomatous Polyposis has 11 registered US clinical trials, 6 of them open to new participants right now, about 55% of the total.
- 6
- recruiting participants now
- 55%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 3
- top sponsor: National Cancer Institute (NCI)
Active & Recent Trials
11 total, page 1 of 1
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT04677998
A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT04678011
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
Recursion Pharmaceuticals
NCT05552755
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
National Cancer Institute (NCI)
NCT05630794
Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
University of Michigan Rogel Cancer Center
NCT06641310
Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis
Abramson Cancer Center at Penn Medicine
NCT06578637
CryoBalloon Ablation for Treatment of Duodenal Adenomas
Johns Hopkins University
NCT03847636
Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
Rapamycin Holdings
NCT04230499
Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
Cancer Prevention Pharmaceuticals
NCT01483144
Curcumin in Treating Patients With Familial Adenomatous Polyposis
National Cancer Institute (NCI)
NCT00641147
Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01
National Cancer Institute (NCI)
NCT04674228
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Familial Adenomatous Polyposis Trial Landscape
11 indexed Familial Adenomatous Polyposis studies · 6 recruiting (55%).
Phase mix: 1 late (III/IV) vs 4 early (I/II).
Top sponsor: National Cancer Institute (NCI) (3 trials), 7 others listed. 11 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Familial Adenomatous Polyposis?
PlainTrial tracks 11 US clinical trials for Familial Adenomatous Polyposis, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Familial Adenomatous Polyposis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.