Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Familial Adenomatous Polyposis: early-phase trial registry
6 of 11 indexed Familial Adenomatous Polyposis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,577 of 28,707 conditions by registered trial count.
11 US clinical trials · 6 currently recruiting · #1,577 of 28,707 conditions by registered trial count
Familial Adenomatous Polyposis: 11 US clinical trials tracked, 6 recruiting.
Familial Adenomatous Polyposis is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.
Enrollment posture brief
Registry condition familial-adenomatous-polyposis
OPEN 6 | RECR 55% | LATE 1 | EARLY 4 | RANK #1577 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Advanced Ovarian Carcinoma (55% recruiting · 11 trials)
Familial Adenomatous Polyposis lists 6 open slots (55% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Familial Adenomatous Polyposis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Familial Adenomatous Polyposis is recruiting above its size-band peers.
6 of 11 indexed trials (54.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Familial Adenomatous Polyposis research.
National Cancer Institute (NCI) accounts for 3 of 11 trials (27.3%). 8 distinct sponsors appear on at least one study for this condition label.
-
Most Familial Adenomatous Polyposis trials plan to enrol fewer than 100 people.
Median target enrolment is 44 among the 11 trials that report a genuine target (sentinel values excluded). 8 of those (72.7%) plan for fewer than 100 participants.
-
Familial Adenomatous Polyposis research is mostly interventional.
8 interventional and 3 observational studies make up this index (72.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
11 total, page 1 of 1
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT04677998
A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT04678011
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
Recursion Pharmaceuticals
NCT05552755
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
National Cancer Institute (NCI)
NCT05630794
Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
University of Michigan Rogel Cancer Center
NCT06641310
Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis
Abramson Cancer Center at Penn Medicine
NCT06578637
CryoBalloon Ablation for Treatment of Duodenal Adenomas
Johns Hopkins University
NCT03847636
Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
Rapamycin Holdings
NCT04230499
Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
Cancer Prevention Pharmaceuticals
NCT01483144
Curcumin in Treating Patients With Familial Adenomatous Polyposis
National Cancer Institute (NCI)
NCT00641147
Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01
National Cancer Institute (NCI)
NCT04674228
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Familial Adenomatous Polyposis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Familial Adenomatous Polyposis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Familial Adenomatous Polyposis page
11 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Familial Adenomatous Polyposis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Cancer Institute (NCI) sponsors the most Familial Adenomatous Polyposis trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Familial Adenomatous Polyposis condition card totals 11 registered trials; most-linked intervention Personalized surveillance and intervention protocol; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.