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NCT05552755 · ClinicalTrials.gov registry record · Phase 1

Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

A Phase 1 study of Familial Adenomatous Polyposis, sponsored by Recursion Pharmaceuticals.

Recruiting
Registry status
Phase 1
Development phase
67
Enrollment target
17
Study locations

NCT05552755: Recruiting Phase 1 study of Familial Adenomatous Polyposis, sponsored by Recursion Pharmaceuticals.

NCT05552755 is a Phase 1 study of Familial Adenomatous Polyposis that is actively recruiting participants, run by Recursion Pharmaceuticals. The registered enrollment target is 67 participants, below the 242-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (72% lower). The trial reports 17 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05552755, a Phase 1 study of Familial Adenomatous Polyposis, is actively recruiting participants, sponsored by Recursion Pharmaceuticals.

RECRUITING
Registry status
Phase 1
Development phase
67 participants
Enrollment target
17
Study locations

Study Summary

This is a multicenter, two-part trial in participants with FAP.

Interventions

  • DRUG Placebo
  • DRUG REC-4881

Study Locations (17)

Arizona

  • Mayo Clinic - Scottsdale - Scottsdale
  • Del Sol Research Management - Tucson

Florida

  • GI Pros - Naples
  • Digestive and Liver Center of Florida - Orlando

Tennessee

  • Gastro One-8110 Walnut Rs - Cordova
  • Vanderbilt Digestive Center - Nashville

Texas

  • Genetic Cancer Prevention Clinic - UT Southwestern - Dallas
  • MD Anderson Cancer Center - Houston

California

  • Medical Associates Research Group - San Diego

Indiana

  • Gastroenterology Health Partners, PLLC - New Albany

Louisiana

  • Tandem Clinical Research - Marrero

Michigan

  • Corewell Health (Spectrum Health Hospitals Colorectal Cancer Multis) - Grand Rapids

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2023-07-10
Est. Completion 2026-07
Phase Phase 1
Recursion Pharmaceuticals

6 total trials

What NCT05552755 shows while recruiting

NCT05552755 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 242-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (72% lower).

The record links to 1 condition, with Familial Adenomatous Polyposis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05552755 lists 17 locations in 13 states (Arizona, Florida, Tennessee).

Frequently Asked Questions

What is clinical trial NCT05552755 about?

NCT05552755 is a clinical study titled "Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)". This is a multicenter, two-part trial in participants with FAP.

What is the current status of trial NCT05552755?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 67 participants. The study started on 2023-07-10. Estimated completion is 2026-07.

What conditions does trial NCT05552755 study?

This clinical trial studies the following conditions: Familial Adenomatous Polyposis.

What interventions are being tested in trial NCT05552755?

The interventions under investigation include: Placebo (DRUG), REC-4881 (DRUG).

Who is sponsoring clinical trial NCT05552755?

This trial is sponsored by Recursion Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05552755 being conducted?

This trial has 17 study locations across Arizona, California, Florida, Indiana, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Familial Adenomatous Polyposis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05552755's enrollment target sits among peer trials

67 4th of 10 higher than 7 of 10 other Familial Adenomatous Polyposis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Familial Adenomatous Polyposis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05552755, the US trial registry maintained by the National Library of Medicine. NCT05552755 (small enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.