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NCT00641147 · ClinicalTrials.gov registry record · Phase 2
Curcumin in Treating Patients With Familial Adenomatous Polyposis
A Phase 2 study of Familial Adenomatous Polyposis, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
- 2
- Study locations
NCT00641147: Completed Phase 2 study of Familial Adenomatous Polyposis, sponsored by National Cancer Institute (NCI).
NCT00641147 is a Phase 2 study of Familial Adenomatous Polyposis that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 44 participants, below the 244-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (82% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00641147, a Phase 2 study of Familial Adenomatous Polyposis, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
- 2
- Study locations
Study Summary
This randomized phase II trial studies curcumin in treating patients with familial adenomatous polyposis. Curcumin may prevent colorectal cancer in patients with a history of rectal polyps or colorectal neoplasia.
Primary Outcome
Average number of polyps in the placebo arm at the end of the study is compared to the average in the curcumin arm
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Laboratory Biomarker Analysis
- DRUG Curcumin
Study Locations (2)
Maryland
- Johns Hopkins University/Sidney Kimmel Cancer Center - Baltimore
Other
- University of Puerto Rico - San Juan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2010-10 |
| Est. Completion | 2016-11-30 |
| Phase | Phase 2 |
What the finished NCT00641147 record still lists
NCT00641147 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 244-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Familial Adenomatous Polyposis appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT00641147 reports a single indexed study location in Maryland, Other.
Frequently Asked Questions
What is clinical trial NCT00641147 about?
NCT00641147 is a clinical study titled "Curcumin in Treating Patients With Familial Adenomatous Polyposis". This randomized phase II trial studies curcumin in treating patients with familial adenomatous polyposis. Curcumin may prevent colorectal cancer in patients with a history of rectal polyps or colorectal neoplasia.
What is the current status of trial NCT00641147?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2010-10. Estimated completion is 2016-11-30.
What conditions does trial NCT00641147 study?
This clinical trial studies the following conditions: Familial Adenomatous Polyposis.
What interventions are being tested in trial NCT00641147?
The interventions under investigation include: Placebo (OTHER), Laboratory Biomarker Analysis (OTHER), Curcumin (DRUG).
Who is sponsoring clinical trial NCT00641147?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00641147 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Familial Adenomatous Polyposis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00641147's enrollment target sits among peer trials
44 5th of 10 higher than 5 of 10 other Familial Adenomatous Polyposis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Familial Adenomatous Polyposis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
ACTIVE NOT RECRUITING · Phase 2
-
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
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-
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