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NCT04678011 · ClinicalTrials.gov registry record
A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
A clinical trial of Familial Adenomatous Polyposis, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 2
- Study locations
NCT04678011: Recruiting study of Familial Adenomatous Polyposis, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).
NCT04678011 is a study of Familial Adenomatous Polyposis that is actively recruiting participants, run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA). The registered enrollment target is 1,000 participants, above the 149-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (571% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04678011, a study of Familial Adenomatous Polyposis, is actively recruiting participants, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.
Primary Outcome
Incidence of advanced neoplasia (advanced adenoma and cancer). An advanced adenoma is defined as size ≥ 10mm and/or high-grade dysplasia. This surveillance and intervention protocol will be considered successful when the incidence of advanced neoplasia is less than 5% after a study period of 5 years.
Conditions Studied
Interventions
- PROCEDURE Personalized surveillance and intervention protocol
Study Locations (2)
Texas
- MD Anderson - Houston
North Holland
- Academic Medical Centre - Amsterdam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2021-11-24 |
| Est. Completion | 2026-11 |
What NCT04678011 shows while recruiting
NCT04678011 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 149-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (571% higher).
The record links to 1 condition, with Familial Adenomatous Polyposis appearing as the primary indexed condition, and to 1 intervention - of which Personalized surveillance and intervention protocol is the first listed.
NCT04678011 reports a single indexed study location in Texas, North Holland.
Frequently Asked Questions
What is clinical trial NCT04678011 about?
NCT04678011 is a clinical study titled "A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy". The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.
What is the current status of trial NCT04678011?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2021-11-24. Estimated completion is 2026-11.
What conditions does trial NCT04678011 study?
This clinical trial studies the following conditions: Familial Adenomatous Polyposis.
What interventions are being tested in trial NCT04678011?
The interventions under investigation include: Personalized surveillance and intervention protocol (PROCEDURE).
Who is sponsoring clinical trial NCT04678011?
This trial is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04678011 being conducted?
This trial has 2 study locations across Texas, North Holland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04678011's enrollment target sits among peer trials
1,000 1st of 10 the highest of 10 other Familial Adenomatous Polyposis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Familial Adenomatous Polyposis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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