Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Epilepsy: early-phase trial registry
78 of 164 indexed Epilepsy trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #65 of 28,707 conditions by registered trial count.
164 US clinical trials · 78 currently recruiting · #65 of 28,707 conditions by registered trial count
Epilepsy: 164 US clinical trials tracked, 78 recruiting.
Epilepsy is the subject of 164 registered US clinical trials on ClinicalTrials.gov, 78 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 39 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Neurological Disorders and Stroke (NINDS), running 9 of these trials.
Enrollment posture brief
Registry condition epilepsy
OPEN 78 | RECR 48% | LATE 21 | EARLY 39 | RANK #65 | SPON 9
Volume-matched condition peers
Nearest open-share peer: Microbial Colonization (48% recruiting · 21 trials)
Epilepsy lists 78 open slots (48% of 164 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Epilepsy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Epilepsy is recruiting above its size-band peers.
78 of 164 indexed trials (47.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Epilepsy trials is spread across many organizations.
National Institute of Neurological Disorders and Stroke (NINDS) accounts for 9 of 164 trials (5.5%). 95 distinct sponsors appear on at least one study for this condition label.
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Most Epilepsy trials plan to enrol fewer than 100 people.
Median target enrolment is 60 among the 161 trials that report a genuine target (sentinel values excluded). 103 of those (64%) plan for fewer than 100 participants.
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Epilepsy research is mostly interventional.
120 interventional and 44 observational studies make up this index (73.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
164 total, page 4 of 4
In Vivo Imaging of Therapeutic Electric Current Flow
University of Florida
NCT02453763
Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy
Mayo Clinic
NCT01703143
Treatment Development of Triheptanoin (G1D)
Juan Pascual
NCT03041363
Efficacy of YKP3089 in Patients With Photosensitive Epilepsy
SK Life Science
NCT00616148
Seizure Detection and Warning System in Epilepsy Patients
Brain Sentinel
NCT02555410
Effect of Haemodialysis on the Pharmacokinetics of Ezogabine/Retigabine and Its N-acetyl Metabolite
GlaxoSmithKline
NCT01480609
CX-8998 for Absence Seizures
Jazz Pharmaceuticals
NCT03406702
Levetiracetam for Benign Rolandic Epilepsy
Johns Hopkins University
NCT00181116
Electroencephalography (EEG) and Deep Brain Stimulation (DBS) in Epilepsy
Weill Medical College of Cornell University
NCT00194870
Presurgical Motor Mapping With Transcranial Magnetic Stimulation (TMS)
NYU Langone Health
NCT02741193
High Definition Cathodal Transcranial Direct Current Stimulation for Treatment of Refractory Partial Onset Epilepsy
NYU Langone Health
NCT02264652
Pediatric Epilepsy Database
University of Alabama at Birmingham
NCT00204360
Double-Blind, Placebo-Controlled Trial of Vitamin E as Add-on Therapy for Children With Epilepsy
National Center for Research Resources (NCRR)
NCT00004637
E2007 Given as Adjunctive Therapy in Patients With Refractory Partial Seizures
Eisai
NCT00144690
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 23 |
| Phase 2 | 16 |
| Phase 3 | 14 |
| Phase 4 | 7 |
Top Sponsors
Named interventions
Most-linked intervention names on Epilepsy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Epilepsy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Epilepsy page
164 registered trials, 78 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 78 Epilepsy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Neurological Disorders and Stroke (NINDS) sponsors the most Epilepsy trials on record, review their full trial history before evaluating a specific study. See National Institute of Neurological Disorders and Stroke (NINDS)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Epilepsy condition card totals 164 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.