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Dystonia clinical trials
Every US clinical trial registered for Dystonia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
29 US clinical trials · 16 currently recruiting
The research picture
Dystonia has 29 registered US clinical trials, 16 of them open to new participants right now — about 55% of the total.
- 16
- recruiting participants now
- 55%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 5
- top sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Boston Scientific Corporation
NCT03664609
Physiological Brain Atlas Development
Vanderbilt University Medical Center
NCT00575081
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Abbott Medical Devices
NCT04071847
Clinical Outcomes for Deep Brain Stimulation
Washington University School of Medicine
NCT03992625
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Massachusetts Eye and Ear Infirmary
NCT05317390
Dystonia Genotype-Phenotype Correlation
University of Texas Southwestern Medical Center
NCT03428009
Deep Brain Stimulation Surgery for Movement Disorders
National Institute of Neurological Disorders and Stroke (NINDS)
NCT01581580
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
State University of New York at Buffalo
NCT00682513
Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
Massachusetts Eye and Ear Infirmary
NCT05150093
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Vima Therapeutics
NCT07304089
Cortical-Basal Ganglia Speech Networks
Massachusetts General Hospital
NCT04286308
Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Children's Hospital Medical Center, Cincinnati
NCT07325175
Sleep-specific DBS Therapy in Parkinson's Disease
University of Minnesota
NCT05962489
Effects of Exercise on Dystonia Pathophysiology
University of Florida
NCT05663840
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
Children's Mercy Hospital Kansas City
NCT06554288
The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy
University of California, San Francis
NCT03582891
Deep Brain Stimulation Surgery for Focal Hand Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02911103
Physiological Brain Atlas Development
Ohio State University
NCT01210534
Fatigue in Dystonia (a Single Session, Questionnaire-based Study of Fatigue in Dystonia)
University of Florida
NCT00954408
Brain Function in Focal Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00102999
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Children's Hospital Medical Center, Cincinnati
NCT03892798
Pathophysiology of Focal Hand Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03223623
Cholinergic Receptor Imaging in Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02689466
Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand
Icahn School of Medicine at Mount Sinai
NCT02107261
Studying Childhood-Onset Hemidystonia
National Institutes of Health Clinical Center (CC)
NCT01432899
Physiology, Imaging and Modeling of Essential Tremor
University of Florida
NCT03811405
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
New York Institute of Technology
NCT03307161
Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults
University of California, San Francis
NCT03078816
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dystonia Trial Landscape
ClinicalTrials.gov lists 29 US studies indexed under Dystonia, and 16 of those are currently open to recruitment — roughly 55% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Dystonia shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Dystonia is led by National Institute of Neurological Disorders and Stroke (NINDS) with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 29 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dystonia?
PlainTrial tracks 29 US clinical trials for Dystonia, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dystonia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.