Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Dystonia: early-phase trial registry
16 of 29 indexed Dystonia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #552 of 28,707 conditions by registered trial count.
29 US clinical trials · 16 currently recruiting · #552 of 28,707 conditions by registered trial count
Dystonia: 29 US clinical trials tracked, 16 recruiting.
Dystonia is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Neurological Disorders and Stroke (NINDS), running 5 of these trials.
Enrollment posture brief
Registry condition dystonia
OPEN 16 | RECR 55% | LATE 0 | EARLY 4 | RANK #552 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Diffuse Intrinsic Pontine Glioma (55% recruiting · 29 trials)
Dystonia lists 16 open slots (55% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Dystonia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Dystonia is recruiting above its size-band peers.
16 of 29 indexed trials (55.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Dystonia research.
National Institute of Neurological Disorders and Stroke (NINDS) accounts for 5 of 29 trials (17.2%). 20 distinct sponsors appear on at least one study for this condition label.
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Typical Dystonia enrolment sits around 80 participants.
Median target enrolment is 80 among the 29 trials that report a genuine target (sentinel values excluded). 15 of those (51.7%) plan for fewer than 100 participants.
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Dystonia splits between interventional and observational designs.
16 interventional and 13 observational studies make up this index (55.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
29 total, page 1 of 1
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Boston Scientific Corporation
NCT03664609
Physiological Brain Atlas Development
Vanderbilt University Medical Center
NCT00575081
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Abbott Medical Devices
NCT04071847
Clinical Outcomes for Deep Brain Stimulation
Washington University School of Medicine
NCT03992625
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Massachusetts Eye and Ear Infirmary
NCT05317390
Dystonia Genotype-Phenotype Correlation
University of Texas Southwestern Medical Center
NCT03428009
Deep Brain Stimulation Surgery for Movement Disorders
National Institute of Neurological Disorders and Stroke (NINDS)
NCT01581580
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
State University of New York at Buffalo
NCT00682513
Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
Massachusetts Eye and Ear Infirmary
NCT05150093
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Vima Therapeutics
NCT07304089
Cortical-Basal Ganglia Speech Networks
Massachusetts General Hospital
NCT04286308
Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Children's Hospital Medical Center, Cincinnati
NCT07325175
Sleep-specific DBS Therapy in Parkinson's Disease
University of Minnesota
NCT05962489
Effects of Exercise on Dystonia Pathophysiology
University of Florida
NCT05663840
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
Children's Mercy Hospital Kansas City
NCT06554288
The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy
University of California, San Francisco
NCT03582891
Deep Brain Stimulation Surgery for Focal Hand Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02911103
Physiological Brain Atlas Development
Ohio State University
NCT01210534
Fatigue in Dystonia (a Single Session, Questionnaire-based Study of Fatigue in Dystonia)
University of Florida
NCT00954408
Brain Function in Focal Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00102999
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Children's Hospital Medical Center, Cincinnati
NCT03892798
Pathophysiology of Focal Hand Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03223623
Cholinergic Receptor Imaging in Dystonia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02689466
Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand
Icahn School of Medicine at Mount Sinai
NCT02107261
Studying Childhood-Onset Hemidystonia
National Institutes of Health Clinical Center (CC)
NCT01432899
Physiology, Imaging and Modeling of Essential Tremor
University of Florida
NCT03811405
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
New York Institute of Technology
NCT03307161
Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults
University of California, San Francisco
NCT03078816
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Dystonia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Dystonia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Dystonia page
29 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 16 Dystonia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Neurological Disorders and Stroke (NINDS) sponsors the most Dystonia trials on record, review their full trial history before evaluating a specific study. See National Institute of Neurological Disorders and Stroke (NINDS)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dystonia condition card totals 29 registered trials; most-linked intervention Deep Brain Stimulation; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.