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NCT06554288 · ClinicalTrials.gov registry record · Phase 1

Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

A Phase 1 study of Dystonia and Genetic Predisposition, sponsored by Children's Mercy Hospital Kansas City.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT06554288 is a Phase 1 study of Dystonia and Genetic Predisposition that is actively recruiting participants, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 40 participants, below the 539-participant average among 28 other Dystonia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06554288, a Phase 1 study of Dystonia and Genetic Predisposition, is actively recruiting participants, sponsored by Children's Mercy Hospital Kansas City.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this is impacted by a person's genetics. Information from this study will also be used to design future clinical trials.

Interventions

  • DRUG Trihexyphenidyl

Study Locations (1)

Missouri

  • Children's Mercy Hospital Kansas City - Kansas City

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-10-15
Est. Completion 2029-12-31
Phase Phase 1

What the Registry Record Tells You About NCT06554288

The ClinicalTrials.gov registry entry for NCT06554288 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 539-participant average among 28 other Dystonia trials with a reported enrollment target (93% lower). The listed sponsor is Children's Mercy Hospital Kansas City, which has 184 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Dystonia appearing as the primary indexed condition, and to 1 intervention - of which Trihexyphenidyl is the first listed.

NCT06554288 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT06554288 about?

NCT06554288 is a clinical study titled "Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy". This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this is impacted by a person's genetics. Information from this study will a...

What is the current status of trial NCT06554288?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2024-10-15. Estimated completion is 2029-12-31.

What conditions does trial NCT06554288 study?

This clinical trial studies the following conditions: Dystonia, Genetic Predisposition, Pediatric Disorder, Pharmacogenomic Drug Interaction, Cerebral Palsy, Dyskinetic.

What interventions are being tested in trial NCT06554288?

The interventions under investigation include: Trihexyphenidyl (DRUG).

Who is sponsoring clinical trial NCT06554288?

This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06554288 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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