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NCT03582891 · ClinicalTrials.gov registry record · NA

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

A NA study of Parkinson Disease and Dystonia, sponsored by University of California, San Francisco.

Active
Registry status
NA
Development phase
25
Enrollment target
1
Study location

NCT03582891 is a NA study of Parkinson Disease and Dystonia that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 25 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03582891, a NA study of Parkinson Disease and Dystonia, is active but no longer recruiting, sponsored by University of California, San Francisco.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

This is an exploratory pilot study to identify neural correlates of specific motor signs in Parkinson's disease (PD) and dystonia, using a novel totally implanted neural interface that senses brain activity as well as delivering therapeutic stimulation. Parkinson's disease and isolated dystonia patients will be implanted unilaterally or bilaterally with a totally internalized bidirectional neural interface, Medtronic Summit RC+S. This study includes three populations: ten PD patients undergoing deep brain stimulation in the subthalamic nucleus (STN), ten PD patients with a globus pallidus (GPi) target and five dystonia patients. All groups will test a variety of strategies for feedback-controlled deep brain stimulation, and all patients will undergo a blinded, small pilot clinical trial of closed-loop stimulation for thirty days.

Interventions

  • DEVICE Summit RC+S for Motor
  • DIAGNOSTIC_TEST 8-week pilot trial of Closed-loop vs. Open-loop Stimulation
  • DEVICE Summit RC+S for Sleep

Study Locations (1)

California

  • University of California at San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2018-10-01
Est. Completion 2028-03
Phase NA

What the Registry Record Tells You About NCT03582891

The ClinicalTrials.gov registry entry for NCT03582891 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 3 interventions - of which Summit RC+S for Motor is the first listed.

NCT03582891 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03582891 about?

NCT03582891 is a clinical study titled "The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy". This is an exploratory pilot study to identify neural correlates of specific motor signs in Parkinson's disease (PD) and dystonia, using a novel totally implanted neural interface that senses brain activity as well as delivering therapeutic stimulation. Parkinson's disease and isolated dystonia pati...

What is the current status of trial NCT03582891?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2018-10-01. Estimated completion is 2028-03.

What conditions does trial NCT03582891 study?

This clinical trial studies the following conditions: Parkinson Disease, Dystonia.

What interventions are being tested in trial NCT03582891?

The interventions under investigation include: Summit RC+S for Motor (DEVICE), 8-week pilot trial of Closed-loop vs. Open-loop Stimulation (DIAGNOSTIC_TEST), Summit RC+S for Sleep (DEVICE).

Who is sponsoring clinical trial NCT03582891?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03582891 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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