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NCT00001726 · ClinicalTrials.gov registry record
Study of the Composition of Dental Plaque
A clinical trial of Dental Caries and Dental Plaque, sponsored by National Institute of Dental and Craniofacial Research (NIDCR).
- Completed
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT00001726 is a study of Dental Caries and Dental Plaque that has completed, run by National Institute of Dental and Craniofacial Research (NIDCR). The registered enrollment target is 50 participants, below the 720-participant average among 30 other Dental Caries trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00001726, a study of Dental Caries and Dental Plaque, has completed, sponsored by National Institute of Dental and Craniofacial Research (NIDCR).
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease. A better understanding of how plaque builds up in the mouth may help in developing improved ways of controlling it. Healthy normal volunteers between the ages of 18 and 65 who work at the National Institutes of Health main campus in Bethesda, Maryland, may participate in this study. Candidates will be screened for eligibility with a medical and dental history. This study involves a maximum of five visits to the dental clinic. At the first visit, participants will have a dental examination, and a mold will be made of the mouth. To make the mold, a small plastic tray containing impression material will be placed in the volunteer's mouth and held in place for about 2 minutes to set. The tray will then be removed and a mold will be made from the impression. The mold will be used to make the mouthpiece used in study 1, described below, and the tooth fittings used in study 2, also described below. Volunteers will participate in one of these two studies. Study 1. Volunteers in study 1 will have their mouthpiece checked at the second visit, have a teeth cleaning, and have the mold put in place. The mouthpiece will be worn for up to 8 hours, during which time soft foods can be eaten. Mouthwash should not be used while the device is in place. At the volunteer's third (last) visit, the mouthpiece will be removed and the volunteer will spit into a tube to collect saliva for examination for bacteria. Study 2. Volunteers in study 2 will have their teeth cleaned at the second visit and the tooth fittings placed onto the back teeth with a dental adhesive. The fittings will be worn for up to 72 hours, during which time volunteers can eat a regular diet and brush their teeth. Mouthwash should not be used while the fittings are in place. At the third, fourth and fifth visits, some of the fittings will be removed and, if necess
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 1998-06-19 |
| Est. Completion | 2009-08-03 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001726
The ClinicalTrials.gov registry entry for NCT00001726 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 720-participant average among 30 other Dental Caries trials with a reported enrollment target (93% lower). The listed sponsor is National Institute of Dental and Craniofacial Research (NIDCR), which has 91 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Dental Caries appearing as the primary indexed condition, and to 0 interventions.
NCT00001726 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001726 about?
NCT00001726 is a clinical study titled "Study of the Composition of Dental Plaque". This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease. A better understanding of how plaque builds up in the mouth may help in developing improved ways of controlling it. Healthy normal volunteers ...
What is the current status of trial NCT00001726?
This trial is currently completed. The enrollment target is 50 participants. The study started on 1998-06-19. Estimated completion is 2009-08-03.
What conditions does trial NCT00001726 study?
This clinical trial studies the following conditions: Dental Caries, Dental Plaque, Periodontal Disease.
Who is sponsoring clinical trial NCT00001726?
This trial is sponsored by National Institute of Dental and Craniofacial Research (NIDCR), which has 91 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001726 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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