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NCT05579938 · ClinicalTrials.gov registry record · NA
Effect of Enzymes on Dental Biofilm Accumulation
A NA study of Dental Plaque, sponsored by Novozymes A/S.
- Completed
- Registry status
- NA
- Development phase
- 28
- Enrollment target
- 1
- Study location
NCT05579938: Completed NA study of Dental Plaque, sponsored by Novozymes A/S.
NCT05579938 is a NA study of Dental Plaque that has completed, run by Novozymes A/S. The registered enrollment target is 28 participants, below the 622-participant average among 10 other Dental Plaque trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05579938, a NA study of Dental Plaque, has completed, sponsored by Novozymes A/S.
- COMPLETED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
Double-blind, placebo-controlled, cross-over study investigating dental biofilm accumulation after 4-days in 28 subjects randomised to receive: Sequence 1: 5 active enzyme-containing lozenges per day for 4-days followed by a 2-week washout period followed by 5 identical placebo lozenges per day for 4-days or Sequence 2: 5 placebo lozenges per day for 4-days followed by a 2-week washout period followed by 5 identical active enzyme lozenges per day for 4-days
Primary Outcome
Biofilm accumulation is assessed by the Lobene-Soparkar Modification of the Turesky Modification of the Quigley-Hein Plaque Index (PLI)
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Enzyme-containing lozenge
- DIETARY_SUPPLEMENT Placebo lozenge
Study Locations (1)
Indiana
- Salus Research Inc - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2022-09-19 |
| Est. Completion | 2022-11-20 |
| Phase | NA |
What the finished NCT05579938 record still lists
NCT05579938 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 622-participant average among 10 other Dental Plaque trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Dental Plaque appearing as the primary indexed condition, and to 2 interventions - of which Enzyme-containing lozenge is the first listed.
NCT05579938 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT05579938 about?
NCT05579938 is a clinical study titled "Effect of Enzymes on Dental Biofilm Accumulation". Double-blind, placebo-controlled, cross-over study investigating dental biofilm accumulation after 4-days in 28 subjects randomised to receive: Sequence 1: 5 active enzyme-containing lozenges per day for 4-days followed by a 2-week washout period followed by 5 identical placebo lozenges per day for...
What is the current status of trial NCT05579938?
This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2022-09-19. Estimated completion is 2022-11-20.
What conditions does trial NCT05579938 study?
This clinical trial studies the following conditions: Dental Plaque.
What interventions are being tested in trial NCT05579938?
The interventions under investigation include: Enzyme-containing lozenge (DIETARY_SUPPLEMENT), Placebo lozenge (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05579938?
This trial is sponsored by Novozymes A/S, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05579938 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dental Plaque
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05579938's enrollment target sits among peer trials
28 9th of 10 higher than 2 of 10 other Dental Plaque trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Plaque trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
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-
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COMPLETED · NA
-
Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque
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