National Institute of Dental and Craniofacial Research (NIDCR)
Trial Pipeline
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
NCT07281456
Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls
NCT03602599
Natural History of Craniofacial Anomalies and Developmental Growth Variants
NCT02639312
Characterization of Diseases With Salivary Gland Involvement
NCT02327884
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
NCT01805869
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
NCT01568697
The Pathogenesis and Natural History of Sjogren's Disease
NCT01425892
Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer
NCT00804154
A Natural History Study of Bone and Mineral Disorders
NCT00024804
Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
NCT00001727
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome
NCT04496960
Denosumab Treatment for Fibrous Dysplasia
NCT03571191
Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s Syndrome
NCT00565526
Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer
NCT00372320
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth
NCT00104026
Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia
NCT00099762
Capsaicin to Control Pain Following Third Molar Extraction
NCT00088686
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
NCT00078351
Studying Phosphorus Metabolism
NCT00066183
Magnets in the Treatment of Sciatica
NCT00044109
A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome
NCT00017927
Pain Evaluation and Treatment
NCT00362167
Pain Treatment for Sciatica
NCT00009672
Oral Manifestations of Aplastic Anemia
NCT00006300
Influence of Genetics in Pain Sensitivity
NCT00001956
Etanercept Therapy for Sjogren's Syndrome
NCT00001954
Celebrex for Pain Relief After Oral Surgery
NCT00006299
Study of the Composition of Dental Plaque
NCT00001726
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
NCT00001725
Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright Syndrome
NCT00001973
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
NCT00001524
Evaluation of Patients With Unusual Diagnostic or Treatment Considerations
NCT00001182
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 11 |
| Phase 3 | 1 |
Therapeutic Areas
What the Pipeline for National Institute of Dental and Craniofacial Research (NIDCR) Shows
According to the ClinicalTrials.gov registry, National Institute of Dental and Craniofacial Research (NIDCR) is linked to 60 US clinical trials across every stage of research activity. Of those, 38 studies are currently recruiting — about 63% of the sponsor's indexed portfolio — and 20 are already marked complete, representing roughly 33% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for National Institute of Dental and Craniofacial Research (NIDCR) reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 14 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for National Institute of Dental and Craniofacial Research (NIDCR) is Sjogren's Syndrome with 6 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.