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ClinicalTrials.gov 11 recruiting now official registry

Deep Brain Stimulation clinical trials

Every US clinical trial registered for Deep Brain Stimulation — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 11 currently recruiting

The research picture

Deep Brain Stimulation has 16 registered US clinical trials, 11 of them open to new participants right now — about 69% of the total.

11
recruiting participants now
69%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: University of Minnesota

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 2 500 participants

A Study of Buntanetap in Participants With PD

Annovis Bio

NCT07284784

RECRUITING NA 144 participants

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles

NCT05417555

RECRUITING 100 participants

Udall Project 1 Aim 4

University of Minnesota

NCT05568199

RECRUITING 100 participants

A Multicenter Pediatric Deep Brain Stimulation Registry

Boston Children's Hospital

NCT06585618

RECRUITING NA 75 participants

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

Children's Hospital Medical Center, Cincinnati

NCT07325175

RECRUITING NA 70 participants

Understanding Motivation in Parkinson's Patients Through Neurophysiology

University of California, San Francis

NCT05065151

RECRUITING NA 64 participants

Sleep-specific DBS Therapy in Parkinson's Disease

University of Minnesota

NCT05962489

RECRUITING 55 participants

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

Medical University of South Carolina

NCT06960096

RECRUITING Phase 4 54 participants

Imaging Biomarkers of FOG Response to DBS

Medical University of South Carolina

NCT06951906

RECRUITING NA 41 participants

Use of CereGate Therapy for Freezing of Gait in PD

CereGate

NCT05292794

RECRUITING Early Phase 1 20 participants

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

University of Minnesota

NCT05493722

ACTIVE NOT RECRUITING Phase 1 12 participants

Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease

James Liao

NCT05022147

COMPLETED 10,981 participants

Implantable Systems Performance Registry

MedtronicNeuro

NCT00959296

COMPLETED NA 22 participants

The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients

Oregon Health and Science University

NCT02947841

COMPLETED NA 10 participants

Music-listening During Deep Brain Stimulation to Relieve Anxiety

Darlene A. Lobel, MD

NCT03091335

COMPLETED NA 2 participants

Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles

NCT03347084

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Deep Brain Stimulation Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Deep Brain Stimulation, and 11 of those are currently open to recruitment — roughly 69% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Deep Brain Stimulation shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Deep Brain Stimulation is led by University of Minnesota with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Deep Brain Stimulation?

PlainTrial tracks 16 US clinical trials for Deep Brain Stimulation, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Deep Brain Stimulation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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