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ClinicalTrials.gov 11 recruiting now early-phase tilt small index

Deep Brain Stimulation: early-phase trial registry

11 of 16 indexed Deep Brain Stimulation trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 11 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Deep Brain Stimulation: 16 US clinical trials tracked, 11 recruiting.

Deep Brain Stimulation is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 3 of these trials.

Enrollment posture brief

Registry condition deep-brain-stimulation

OPEN 11 | RECR 69% | LATE 1 | EARLY 3 | RANK #1060 | SPON 3

Nearest open-share peer: Hepatocellular Carcinoma (HCC) (69% recruiting · 16 trials)

Deep Brain Stimulation (this)69%Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Deep Brain Stimulation

Deep Brain Stimulation lists 11 open slots (69% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Deep Brain Stimulation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Deep Brain Stimulation is recruiting above its size-band peers.

    11 of 16 indexed trials (68.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Deep Brain Stimulation research.

    University of Minnesota accounts for 3 of 16 trials (18.8%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Deep Brain Stimulation trials plan to enrol fewer than 100 people.

    Median target enrolment is 64 among the 16 trials that report a genuine target (sentinel values excluded). 11 of those (68.8%) plan for fewer than 100 participants.

  4. Deep Brain Stimulation research is mostly interventional.

    12 interventional and 4 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 21Phase 41

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 2 500 participants

A Study of Buntanetap in Participants With PD

Annovis Bio

NCT07284784

RECRUITING NA 144 participants

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles

NCT05417555

RECRUITING 100 participants

Udall Project 1 Aim 4

University of Minnesota

NCT05568199

RECRUITING 100 participants

A Multicenter Pediatric Deep Brain Stimulation Registry

Boston Children's Hospital

NCT06585618

RECRUITING NA 75 participants

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

Children's Hospital Medical Center, Cincinnati

NCT07325175

RECRUITING NA 70 participants

Understanding Motivation in Parkinson's Patients Through Neurophysiology

University of California, San Francisco

NCT05065151

RECRUITING NA 64 participants

Sleep-specific DBS Therapy in Parkinson's Disease

University of Minnesota

NCT05962489

RECRUITING 55 participants

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

Medical University of South Carolina

NCT06960096

RECRUITING Phase 4 54 participants

Imaging Biomarkers of FOG Response to DBS

Medical University of South Carolina

NCT06951906

RECRUITING NA 41 participants

Use of CereGate Therapy for Freezing of Gait in PD

CereGate

NCT05292794

RECRUITING Early Phase 1 20 participants

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

University of Minnesota

NCT05493722

ACTIVE NOT RECRUITING Phase 1 12 participants

Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease

James Liao

NCT05022147

COMPLETED 10,981 participants

Implantable Systems Performance Registry

MedtronicNeuro

NCT00959296

COMPLETED NA 22 participants

The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients

Oregon Health and Science University

NCT02947841

COMPLETED NA 10 participants

Music-listening During Deep Brain Stimulation to Relieve Anxiety

Darlene A. Lobel, MD

NCT03091335

COMPLETED NA 2 participants

Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles

NCT03347084

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Deep Brain Stimulation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Music-listening Other
1 trials
Various Device
1 trials
Alternating stimulation Other
1 trials
Inhibition Device
1 trials
Excitation Device
1 trials
Alternating, 10 sec High-Frequency, 50 sec Low-Frequency Stimulation Device
1 trials
Alternating, 50 sec High-Frequency, 50 sec Low-Frequency Stimulation Device
1 trials
Alternating, 50 sec High-Frequency, 10 sec Low-Frequency Stimulation Device
1 trials

US sites by state

Facility locations filed on Deep Brain Stimulation trials. A trial with sites in several states counts in each.

California 6 trials
Ohio 4 trials
Minnesota 3 trials
Florida 3 trials
South Carolina 2 trials
North Carolina 2 trials
Indiana 2 trials
Illinois 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Deep Brain Stimulation page

16 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Deep Brain Stimulation condition card totals 16 registered trials; most-linked intervention Music-listening; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.