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Deep Brain Stimulation clinical trials
Every US clinical trial registered for Deep Brain Stimulation — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
16 US clinical trials · 11 currently recruiting
The research picture
Deep Brain Stimulation has 16 registered US clinical trials, 11 of them open to new participants right now — about 69% of the total.
- 11
- recruiting participants now
- 69%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 3
- top sponsor: University of Minnesota
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Study of Buntanetap in Participants With PD
Annovis Bio
NCT07284784
Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease
University of California, Los Angeles
NCT05417555
Udall Project 1 Aim 4
University of Minnesota
NCT05568199
A Multicenter Pediatric Deep Brain Stimulation Registry
Boston Children's Hospital
NCT06585618
Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Children's Hospital Medical Center, Cincinnati
NCT07325175
Understanding Motivation in Parkinson's Patients Through Neurophysiology
University of California, San Francis
NCT05065151
Sleep-specific DBS Therapy in Parkinson's Disease
University of Minnesota
NCT05962489
Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study
Medical University of South Carolina
NCT06960096
Imaging Biomarkers of FOG Response to DBS
Medical University of South Carolina
NCT06951906
Use of CereGate Therapy for Freezing of Gait in PD
CereGate
NCT05292794
Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
University of Minnesota
NCT05493722
Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease
James Liao
NCT05022147
Implantable Systems Performance Registry
MedtronicNeuro
NCT00959296
The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients
Oregon Health and Science University
NCT02947841
Music-listening During Deep Brain Stimulation to Relieve Anxiety
Darlene A. Lobel, MD
NCT03091335
Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease
University of California, Los Angeles
NCT03347084
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Deep Brain Stimulation Trial Landscape
ClinicalTrials.gov lists 16 US studies indexed under Deep Brain Stimulation, and 11 of those are currently open to recruitment — roughly 69% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Deep Brain Stimulation shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Deep Brain Stimulation is led by University of Minnesota with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Deep Brain Stimulation?
PlainTrial tracks 16 US clinical trials for Deep Brain Stimulation, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Deep Brain Stimulation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.