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NCT02947841 · ClinicalTrials.gov registry record · NA

The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients

A NA study of Essential Tremor and Deep Brain Stimulation, sponsored by Oregon Health and Science University.

Completed
Registry status
NA
Development phase
22
Enrollment target
1
Study location

NCT02947841: Completed NA study of Essential Tremor and Deep Brain Stimulation, sponsored by Oregon Health and Science University.

NCT02947841 is a NA study of Essential Tremor and Deep Brain Stimulation that has completed, run by Oregon Health and Science University. The registered enrollment target is 22 participants, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02947841, a NA study of Essential Tremor and Deep Brain Stimulation, has completed, sponsored by Oregon Health and Science University.

COMPLETED
Registry status
NA
Development phase
22 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate the hypothesis that alternating DBS parameters on a weekly basis will prevent tolerance to stimulation and thus waning of benefit, compared with non-alternating stimulation. The primary endpoint will be preserved tremor control with the alternating group compared with standard treatment using the Tremor Research Group Essential Tremor Rating Assessment Scale (TETRAS). Key secondary endpoints will be preserved activities of daily living measures as well as preserved tremor control as quantified by motion sensor data. This study has one primary aim: To determine if alternating DBS stimulation parameters on a weekly basis will be superior at preserving tremor control compared with usual stimulation (non-alternating stimulation) in ET patients with VIM DBS.

Interventions

  • OTHER Placebo
  • OTHER Alternating stimulation

Study Locations (1)

Oregon

  • Oregon Health Science and University - Portland

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2016-10
Est. Completion 2017-07
Phase NA

What the finished NCT02947841 record still lists

NCT02947841 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (95% lower).

The record links to 2 conditions, with Essential Tremor appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02947841 reports a single indexed study location in Oregon.

Frequently Asked Questions

What is clinical trial NCT02947841 about?

NCT02947841 is a clinical study titled "The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients". The purpose of this study is to investigate the hypothesis that alternating DBS parameters on a weekly basis will prevent tolerance to stimulation and thus waning of benefit, compared with non-alternating stimulation. The primary endpoint will be preserved tremor control with the alternating group c...

What is the current status of trial NCT02947841?

This trial is currently completed. It is a NA study. The enrollment target is 22 participants. The study started on 2016-10. Estimated completion is 2017-07.

What conditions does trial NCT02947841 study?

This clinical trial studies the following conditions: Essential Tremor, Deep Brain Stimulation.

What interventions are being tested in trial NCT02947841?

The interventions under investigation include: Placebo (OTHER), Alternating stimulation (OTHER).

Who is sponsoring clinical trial NCT02947841?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02947841 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Essential Tremor

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02947841's enrollment target sits among peer trials

22 34th of 41 higher than 8 of 41 other Essential Tremor trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Essential Tremor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02947841, the US trial registry maintained by the National Library of Medicine. NCT02947841 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.