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NCT06951906 · ClinicalTrials.gov registry record · Phase 4
Imaging Biomarkers of FOG Response to DBS
A Phase 4 study of Deep Brain Stimulation and Freezing of Gait Symptoms in Parkinson's Disease, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 54
- Enrollment target
- 1
- Study location
NCT06951906: Recruiting Phase 4 study of Deep Brain Stimulation and Freezing of Gait Symptoms in Parkinson's Disease, sponsored by Medical University of South Carolina.
NCT06951906 is a Phase 4 study of Deep Brain Stimulation and Freezing of Gait Symptoms in Parkinson's Disease that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 54 participants, below the 813-participant average among 15 other Deep Brain Stimulation trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06951906, a Phase 4 study of Deep Brain Stimulation and Freezing of Gait Symptoms in Parkinson's Disease, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 54 participants
- Enrollment target
- 1
- Study location
Study Summary
For this study, the investigators are recruiting 54 individuals with Parkinson's Disease and Freezing of Gait (FOG) who are planning to undergo Deep Brain Stimulation (DBS). The objective of this study is to better understand the FOG response to DBS. Prior to DBS, participants will undergo an MRI scan, behavioral assessment related to walking, a cognitive evaluation, and assessment of other Parkinson's disease symptoms. Following DBS, participants will repeat these assessments at multiple timepoints over the period of one year. Overall, participants will complete a total of 7 visits over a period of approximately 1 year.
Primary Outcome
Turn duration is measured during the timed up and go (TUG) task. Subjects are instrumented with inertial measurement units (IMUs), and turn duration is measured from the first step onto a marked box to the last toe off the box during the turn.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST fMRI
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2024-11-11 |
| Est. Completion | 2030-01 |
| Phase | Phase 4 |
What NCT06951906 shows while recruiting
NCT06951906 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 813-participant average among 15 other Deep Brain Stimulation trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Deep Brain Stimulation appearing as the primary indexed condition, and to 1 intervention - of which fMRI is the first listed.
NCT06951906 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT06951906 about?
NCT06951906 is a clinical study titled "Imaging Biomarkers of FOG Response to DBS". For this study, the investigators are recruiting 54 individuals with Parkinson's Disease and Freezing of Gait (FOG) who are planning to undergo Deep Brain Stimulation (DBS). The objective of this study is to better understand the FOG response to DBS. Prior to DBS, participants will undergo an MRI sc...
What is the current status of trial NCT06951906?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 54 participants. The study started on 2024-11-11. Estimated completion is 2030-01.
What conditions does trial NCT06951906 study?
This clinical trial studies the following conditions: Deep Brain Stimulation, Freezing of Gait Symptoms in Parkinson's Disease.
What interventions are being tested in trial NCT06951906?
The interventions under investigation include: fMRI (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06951906?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06951906 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06951906's enrollment target sits among peer trials
54 10th of 15 higher than 6 of 15 other Deep Brain Stimulation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Deep Brain Stimulation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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