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RECRUITING Phase 2

A Study of Buntanetap in Participants With PD

NCT07284784 · View on ClinicalTrials.gov ↗

Study Summary

This study will examine the long-term safety of buntanetap in participants with PD. This will be a 36-month open-label safety study. This study will be conducted with two cohorts. Cohort 1 will enroll via invitation only for PD participants who have previously participated in buntanetap clinical trials. Cohort 2 will be for PD participants who are receiving deep brain stimulation (DBS) treatment. Qualified participants will receive buntanetap 30mg QD after a screening period of up to 42 days.

Interventions

  • DRUG buntanetap/posiphen

Study Locations (20)

Florida

  • First Choice Neurology - Aventura Neurologic Associates — Aventura
  • Arrow Clinical Trials — Daytona Beach
  • Accel Clinical Sites-Georgia LLC dba Accel Research Sites-Lake Oconee CRU — DeLand
  • Renstar Medical Research — Ocala
  • University of South Florida (USF) - University of South Florida College of Medicine - Parkinson's Di — Tampa
  • Conquest Research — Winter Park

Alabama

  • University of Alabama at Birmingham — Birmingham

Arizona

  • Banner Sun Health Research Institute - Cleo Roberts Center for Clinical Research — Sun City

California

  • Parkinson's & Movement Disorder Institute (PMDI) - Orange County Office — Fountain Valley

Colorado

  • Cenexel Rocky Mountain Clinical Research — Englewood

Connecticut

  • New England Institute for Clinical Research (Ki Health Partners) — Stamford

Georgia

  • iResearch Atlanta — Decatur

Indiana

  • Josephson Wallack Munshower Neurology, P.C. — Indianapolis

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2026-01-09
Est. Completion 2029-11
Phase Phase 2

Sponsor

Annovis Bio

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07284784

The ClinicalTrials.gov registry entry for NCT07284784 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Annovis Bio, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Deep Brain Stimulation appearing as the primary indexed condition, and to 1 intervention — of which buntanetap/posiphen is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07284784 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Florida, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07284784 about?

NCT07284784 is a clinical study titled "A Study of Buntanetap in Participants With PD". This study will examine the long-term safety of buntanetap in participants with PD. This will be a 36-month open-label safety study. This study will be conducted with two cohorts. Cohort 1 will enroll via invitation only for PD participants who have previously participated in buntanetap clinical tri...

What is the current status of trial NCT07284784?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 500 participants. The study started on 2026-01-09. Estimated completion is 2029-11.

What conditions does trial NCT07284784 study?

This clinical trial studies the following conditions: Deep Brain Stimulation, Parkinson's Disease (PD). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07284784?

The interventions under investigation include: buntanetap/posiphen (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07284784?

This trial is sponsored by Annovis Bio, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07284784 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial