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NCT05417555 · ClinicalTrials.gov registry record · NA

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

A NA study of Mild Cognitive Impairment and Deep Brain Stimulation, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
144
Enrollment target
1
Study location

NCT05417555 is a NA study of Mild Cognitive Impairment and Deep Brain Stimulation that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 144 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05417555, a NA study of Mild Cognitive Impairment and Deep Brain Stimulation, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
144 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to investigate whether Low Intensity Focused Ultrasound Pulsation (LIFUP) targeting a part of the brain involved in memory will have an affect on brain activity and whether it may improve memory in people with Mild Cognitive Impairment and Mild Alzheimer's Disease. The main questions the study seeks to answer are: 1. Can LIFUP increase brain activity in the targeted area? 2. Can LIFUP improve memory in people with MCI and mild AD? 3. Can LIFUP improve connectivity of memory networks in the brain? Participants in this study will complete MRIs and memory testing, and receive Low Intensity Focused Ultrasound to a part of their brain involved in memory (the entorhinal cortex).

Interventions

  • DEVICE Low-Intensity Focused Ultrasound Pulsation (LIFUP)

Study Locations (1)

California

  • UCLA Semel Institute for Neuroscience and Behavior - Los Angeles

Trial Details

FieldValue
Enrollment Target 144 participants
Start Date 2022-09-01
Est. Completion 2026-07-31
Phase NA

What the Registry Record Tells You About NCT05417555

The ClinicalTrials.gov registry entry for NCT05417555 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 144 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (89% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which Low-Intensity Focused Ultrasound Pulsation (LIFUP) is the first listed.

NCT05417555 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05417555 about?

NCT05417555 is a clinical study titled "Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease". The goal of this study is to investigate whether Low Intensity Focused Ultrasound Pulsation (LIFUP) targeting a part of the brain involved in memory will have an affect on brain activity and whether it may improve memory in people with Mild Cognitive Impairment and Mild Alzheimer's Disease. The mai...

What is the current status of trial NCT05417555?

This trial is currently recruiting. It is a NA study. The enrollment target is 144 participants. The study started on 2022-09-01. Estimated completion is 2026-07-31.

What conditions does trial NCT05417555 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment, Deep Brain Stimulation, Amnestic Mild Cognitive Disorder, Mild Alzheimer's Disease.

What interventions are being tested in trial NCT05417555?

The interventions under investigation include: Low-Intensity Focused Ultrasound Pulsation (LIFUP) (DEVICE).

Who is sponsoring clinical trial NCT05417555?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05417555 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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