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NCT06960096 · ClinicalTrials.gov registry record
Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study
A clinical trial of Parkinson Disease and Deep Brain Stimulation, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- 55
- Enrollment target
- 1
- Study location
NCT06960096 is a study of Parkinson Disease and Deep Brain Stimulation that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 55 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06960096, a study of Parkinson Disease and Deep Brain Stimulation, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this research study is to understand how Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) affects cognitive networks in the brain, potentially leading to cognitive decline in patients with Parkinson's Disease (PD). A total of 55 participants with PD who have undergone DBS surgery will be recruited from MUSC's Clinical DBS Program. Participants will attend two post-DBS visits: a 3-hour visit for consent, demographic, and cognitive assessments, and a 3-hour DBS-MRI visit to evaluate brain network connectivity with stimulation ON and OFF. These findings will help improve patient selection for surgery and optimize the selection of stimulation targets that minimize undesirable cognitive side effects.
Conditions Studied
Interventions
- OTHER DBS combined with fMRI
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2025-08-21 |
| Est. Completion | 2028-04-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06960096
The ClinicalTrials.gov registry entry for NCT06960096 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which DBS combined with fMRI is the first listed.
NCT06960096 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.
Frequently Asked Questions
What is clinical trial NCT06960096 about?
NCT06960096 is a clinical study titled "Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study". The objective of this research study is to understand how Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) affects cognitive networks in the brain, potentially leading to cognitive decline in patients with Parkinson's Disease (PD). A total of 55 participants with PD who have unde...
What is the current status of trial NCT06960096?
This trial is currently recruiting. The enrollment target is 55 participants. The study started on 2025-08-21. Estimated completion is 2028-04-01.
What conditions does trial NCT06960096 study?
This clinical trial studies the following conditions: Parkinson Disease, Deep Brain Stimulation.
What interventions are being tested in trial NCT06960096?
The interventions under investigation include: DBS combined with fMRI (OTHER).
Who is sponsoring clinical trial NCT06960096?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06960096 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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