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ClinicalTrials.gov 33 recruiting now full pipeline

Congenital Heart Disease: full-pipeline trial registry

33 of 64 indexed Congenital Heart Disease trials are currently recruiting.

Corpus placement: #215 of 28,707 conditions by registered trial count.

64 US clinical trials · 33 currently recruiting · #215 of 28,707 conditions by registered trial count

Congenital Heart Disease: 64 US clinical trials tracked, 33 recruiting.

Congenital Heart Disease is the subject of 64 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 9 of these trials.

Enrollment posture brief

Registry condition congenital-heart-disease

OPEN 33 | RECR 52% | LATE 3 | EARLY 4 | RANK #215 | SPON 9

Nearest open-share peer: Cutaneous Melanoma (52% recruiting · 31 trials)

Anatomic Stage I Breast Canc54.7%Congenital Heart Disease (th…52%Pulmonary Arterial Hypertens32.8%Non-Hodgkin's Lymphoma18.8%Diabetic Macular Edema15.6%
Open-enrollment share among volume-matched conditions near Congenital Heart Disease

Congenital Heart Disease lists 33 open slots (52% of 64 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Congenital Heart Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Congenital Heart Disease is recruiting above its size-band peers.

    33 of 64 indexed trials (51.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Congenital Heart Disease trials is spread across many organizations.

    Boston Children's Hospital accounts for 9 of 64 trials (14.1%). 42 distinct sponsors appear on at least one study for this condition label.

  3. Typical Congenital Heart Disease enrolment sits around 92 participants.

    Median target enrolment is 92 among the 64 trials that report a genuine target (sentinel values excluded). 33 of those (51.6%) plan for fewer than 100 participants.

  4. Congenital Heart Disease splits between interventional and observational designs.

    34 interventional and 30 observational studies make up this index (53.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 21Phase 33

Open and recent trials

64 total, page 2 of 2

COMPLETED NA 65 participants

Improving Motor Skill Development in Infants After Cardiac Surgery

University of Michigan

NCT02700646

COMPLETED 64 participants

Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus

University of Utah

NCT03551600

COMPLETED Phase 3 63 participants

Acute Normovolemic Hemodilution in Complex Cardiac Surgery

University of California, Los Angeles

NCT05049590

COMPLETED 53 participants

Platelet and Tissue cAMP: Novel Biomarkers of Milrinone Efficacy in Children

University of Colorado, Denver

NCT02728128

COMPLETED NA 51 participants

Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements

University of California, Davis

NCT05637814

COMPLETED 40 participants

Does Modified Ultrafiltration Affect Thromboelastography Results?

Wake Forest University Health Sciences

NCT03214120

COMPLETED 40 participants

Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis

Boston Children's Hospital

NCT02352675

COMPLETED NA 30 participants

Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass

Vanderbilt University Medical Center

NCT01228305

COMPLETED 28 participants

Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome

Emory University

NCT00399555

COMPLETED NA 25 participants

MyHeartBaby: An Initial Evaluation of the MyHeartBaby Psychosocial Telemedicine Program

Emory University

NCT02895334

COMPLETED NA 23 participants

Enhanced External Counterpulsation in Patients With Fontan Circulation

Boston Children's Hospital

NCT04956952

COMPLETED NA 21 participants

Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children

Vanderbilt University Medical Center

NCT00848250

COMPLETED NA 12 participants

Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training

Boston Children's Hospital

NCT01977222

COMPLETED Phase 1 10 participants

Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells

Timothy J Nelson, MD, PhD

NCT02549625

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 3

Named interventions

Most-linked intervention names on Congenital Heart Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Harmony TPV System Device
2 trials
MRI Diagnostic test
2 trials
Web-based Educational Intervention Behavioral
1 trials
This is an observational study, there is no intervention Other
1 trials
MyHeartBaby Program Behavioral
1 trials
Near-infrared spectroscopy (NIRS) Procedure
1 trials
No ACE Inhibitor Other
1 trials
Angiotensin Converting Enzyme Inhibitor Drug
1 trials

US sites by state

Facility locations filed on Congenital Heart Disease trials. A trial with sites in several states counts in each.

Massachusetts 16 trials
Ohio 15 trials
California 14 trials
New York 11 trials
Georgia 10 trials
Pennsylvania 9 trials
Minnesota 9 trials
Utah 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Congenital Heart Disease page

64 registered trials, 33 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Congenital Heart Disease condition card totals 64 registered trials; most-linked intervention Harmony TPV System; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.