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Congenital Heart Disease clinical trials
33 of 64 indexed Congenital Heart Disease trials are currently recruiting.
64 US clinical trials · 33 currently recruiting
Congenital Heart Disease is the subject of 64 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 9 of these trials.
The research picture
Congenital Heart Disease has 64 registered US clinical trials, 33 of them open to new participants right now, about 52% of the total.
- 33
- recruiting participants now
- 52%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 9
- top sponsor: Boston Children's Hospital
Active & Recent Trials
64 total, page 2 of 2
Improving Motor Skill Development in Infants After Cardiac Surgery
University of Michigan
NCT02700646
Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus
University of Utah
NCT03551600
Acute Normovolemic Hemodilution in Complex Cardiac Surgery
University of California, Los Angeles
NCT05049590
Platelet and Tissue cAMP: Novel Biomarkers of Milrinone Efficacy in Children
University of Colorado, Denver
NCT02728128
Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements
University of California, Davis
NCT05637814
Does Modified Ultrafiltration Affect Thromboelastography Results?
Wake Forest University Health Sciences
NCT03214120
Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis
Boston Children's Hospital
NCT02352675
Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
Vanderbilt University Medical Center
NCT01228305
Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome
Emory University
NCT00399555
MyHeartBaby: An Initial Evaluation of the MyHeartBaby Psychosocial Telemedicine Program
Emory University
NCT02895334
Enhanced External Counterpulsation in Patients With Fontan Circulation
Boston Children's Hospital
NCT04956952
Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children
Vanderbilt University Medical Center
NCT00848250
Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training
Boston Children's Hospital
NCT01977222
Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells
Timothy J Nelson, MD, PhD
NCT02549625
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Congenital Heart Disease Trial Landscape
64 indexed Congenital Heart Disease studies · 33 recruiting (52%).
Phase mix: 3 late (III/IV) vs 4 early (I/II).
Top sponsor: Boston Children's Hospital (9 trials), 9 others listed. 14 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Congenital Heart Disease?
PlainTrial tracks 64 US clinical trials for Congenital Heart Disease, of which 33 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Congenital Heart Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.