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ClinicalTrials.gov 12 recruiting now early-phase tilt

Non-Hodgkin's Lymphoma: early-phase trial registry

12 of 64 indexed Non-Hodgkin's Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #215 of 28,707 conditions by registered trial count.

64 US clinical trials · 12 currently recruiting · #215 of 28,707 conditions by registered trial count

Non-Hodgkin's Lymphoma: 64 US clinical trials tracked, 12 recruiting.

Non-Hodgkin's Lymphoma is the subject of 64 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 54 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 6 of these trials.

Enrollment posture brief

Registry condition non-hodgkins-lymphoma

OPEN 12 | RECR 19% | LATE 5 | EARLY 54 | RANK #215 | SPON 6

Nearest open-share peer: Allergy (19% recruiting · 16 trials)

Anatomic Stage I Breast Canc54.7%Congenital Heart Disease51.6%Pulmonary Arterial Hypertens32.8%Non-Hodgkin's Lymphoma (this)19%Diabetic Macular Edema15.6%
Open-enrollment share among volume-matched conditions near Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma lists 12 open slots (19% of 64 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Non-Hodgkin's Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Non-Hodgkin's Lymphoma is recruiting below its size-band peers.

    12 of 64 indexed trials (18.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Non-Hodgkin's Lymphoma trials is spread across many organizations.

    Baylor College of Medicine accounts for 6 of 64 trials (9.4%). 39 distinct sponsors appear on at least one study for this condition label.

  3. Most Non-Hodgkin's Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 46 among the 64 trials that report a genuine target (sentinel values excluded). 45 of those (70.3%) plan for fewer than 100 participants.

  4. Non-Hodgkin's Lymphoma research is mostly interventional.

    59 interventional and 5 observational studies make up this index (92.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 127Phase 227Phase 35

Open and recent trials

64 total, page 1 of 2

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING 2,000 participants

ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

Stanford University

NCT02848274

RECRUITING 1,500 participants

Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies

Dana-Farber Cancer Institute

NCT00131014

RECRUITING Phase 1 940 participants

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Hoffmann-La Roche

NCT03075696

RECRUITING Phase 2 490 participants

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Merck Sharp & Dohme

NCT04728893

RECRUITING Phase 1 165 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma

AbbVie

NCT06667687

RECRUITING Phase 1 150 participants

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

AbbVie

NCT05618028

RECRUITING Phase 1 136 participants

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

Baylor College of Medicine

NCT01555892

RECRUITING Phase 2 132 participants

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

National Cancer Institute (NCI)

NCT04002947

RECRUITING Phase 2 78 participants

A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL

Ascentage Pharma Group

NCT04496349

RECRUITING Phase 2 54 participants

Cord Blood Transplant in Adults With Blood Cancers

Memorial Sloan Kettering Cancer Center

NCT05884333

RECRUITING Phase 1 21 participants

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Estrella Biopharma

NCT06343311

ACTIVE NOT RECRUITING Phase 3 165 participants

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

AbbVie

NCT03844048

ACTIVE NOT RECRUITING Phase 2 82 participants

Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Memorial Sloan Kettering Cancer Center

NCT01746849

ACTIVE NOT RECRUITING Phase 1 68 participants

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Baylor College of Medicine

NCT00840853

ACTIVE NOT RECRUITING Early Phase 1 63 participants

PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study

Memorial Sloan Kettering Cancer Center

NCT01269593

ACTIVE NOT RECRUITING Phase 2 33 participants

Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma

National Cancer Institute (NCI)

NCT03789240

ACTIVE NOT RECRUITING Phase 2 30 participants

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT03198026

ACTIVE NOT RECRUITING Phase 1 18 participants

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma

Baylor College of Medicine

NCT01192464

ACTIVE NOT RECRUITING Phase 1 17 participants

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT01840566

ACTIVE NOT RECRUITING Phase 1 10 participants

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Baylor College of Medicine

NCT00710892

ACTIVE NOT RECRUITING Phase 1 7 participants

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)

Baylor College of Medicine

NCT02050347

ACTIVE NOT RECRUITING Phase 1 6 participants

Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)

Sana Biotechnology

NCT06285422

COMPLETED 2,378 participants

Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma

National Cancer Institute (NCI)

NCT00341952

COMPLETED Phase 3 676 participants

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Millennium Pharmaceuticals

NCT00312845

COMPLETED Phase 3 447 participants

Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With R-CVP or R-CHOP in the First-Line Treatment of Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) - Referred to as the BRIGHT Study

Teva Branded Pharmaceutical Products R&D

NCT00877006

COMPLETED Phase 1 320 participants

An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma

Bristol-Myers Squibb

NCT01592370

COMPLETED Phase 2 264 participants

Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant

David Rizzieri, MD

NCT00597714

COMPLETED Phase 2 175 participants

GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma

Hoffmann-La Roche

NCT00576758

COMPLETED Phase 1 160 participants

Ublituximab in Combination With TGR-1202 +/- Ibrutinib or Bendamustine in Patients With B-cell Malignancies

TG Therapeutics

NCT02006485

COMPLETED Phase 3 135 participants

Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss

M.D. Anderson Cancer Center

NCT00352846

COMPLETED Phase 1 133 participants

A Study of Obinutuzumab, Rituximab, Polatuzumab Vedotin, and Venetoclax in Relapsed or Refractory Follicular Lymphoma (FL) or Diffuse Large B-Cell Lymphoma (DLBCL)

Hoffmann-La Roche

NCT02611323

COMPLETED Phase 2 96 participants

Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor

Memorial Sloan Kettering Cancer Center

NCT00582933

COMPLETED Phase 1 82 participants

Study of hA20 (Humanized Anti-CD20) in Patients With CD20+ Non-Hodgkin's Lymphoma

Gilead Sciences

NCT00285428

COMPLETED Phase 2 75 participants

Amifostine for Head and Neck Irradiation in Lymphoma

Dana-Farber Cancer Institute

NCT00136474

COMPLETED Phase 1 66 participants

A Study of Escalating Doses of DCDS0780A in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma

Hoffmann-La Roche

NCT02453087

COMPLETED Phase 3 54 participants

Study to Assess the Effect of Treatment With Bendamustine in Combination With Rituximab on QT Interval in Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL)

Cephalon

NCT01073163

COMPLETED Phase 2 49 participants

A Randomized Study of EPOCH II Versus EPOCH II and Immunotherapy in Lymphomas

National Cancer Institute (NCI)

NCT00001430

COMPLETED 48 participants

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Duke University

NCT01904175

COMPLETED Phase 2 46 participants

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Baylor College of Medicine

NCT00368355

COMPLETED Phase 2 43 participants

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

Celgene

NCT00179673

COMPLETED Phase 1 42 participants

VELCADE®-BEAM and Autologous Hematopoietic Stem Cell Transplantation for Non-Hodgkin's Lymphoma, or Mantle Cell Lymphoma

University of Nebraska

NCT00571493

COMPLETED Phase 2 40 participants

Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma

University of Wisconsin, Madison

NCT01281917

COMPLETED Phase 1 39 participants

Study of the Efficacy and Safety of Ublituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

TG Therapeutics

NCT01647971

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francisco

NCT00516152

COMPLETED Phase 1 35 participants

A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma

Amgen

NCT02961881

COMPLETED Phase 2 33 participants

Reduced Intensity Double Umbilical Cord Blood Transplantation

Massachusetts General Hospital

NCT01408563

COMPLETED Phase 2 32 participants

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

Massachusetts General Hospital

NCT00133367

COMPLETED Phase 2 31 participants

Meloxicam vs Placebo for Mobilization

Massachusetts General Hospital

NCT02003625

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

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Phase Distribution

PhaseTrial count
Phase 1 27
Phase 2 27
Phase 3 5

Named interventions

Most-linked intervention names on Non-Hodgkin's Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Rituximab Drug
4 trials
Melphalan Drug
3 trials
Fludarabine Drug
3 trials
Obinutuzumab Drug
3 trials
rituximab Drug
2 trials
Rituximab Biological
2 trials
Etoposide Drug
2 trials
Cyclophosphamide Drug
2 trials

US sites by state

Facility locations filed on Non-Hodgkin's Lymphoma trials. A trial with sites in several states counts in each.

Texas 18 trials
California 17 trials
New York 15 trials
Florida 10 trials
New Jersey 9 trials
Massachusetts 9 trials
Washington 8 trials
North Carolina 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Non-Hodgkin's Lymphoma page

64 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Non-Hodgkin's Lymphoma condition card totals 64 registered trials; most-linked intervention Rituximab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.