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ClinicalTrials.gov 12 recruiting now official registry

Non-Hodgkin's Lymphoma clinical trials

12 of 64 indexed Non-Hodgkin's Lymphoma trials are currently recruiting.

64 US clinical trials · 12 currently recruiting

Non-Hodgkin's Lymphoma is the subject of 64 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 54 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 6 of these trials.

The research picture

Non-Hodgkin's Lymphoma has 64 registered US clinical trials, 12 of them open to new participants right now, about 19% of the total.

12
recruiting participants now
19%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
6
top sponsor: Baylor College of Medicine
Phase 127Phase 227Phase 35

Active & Recent Trials

64 total, page 1 of 2

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING 2,000 participants

ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

Stanford University

NCT02848274

RECRUITING 1,500 participants

Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies

Dana-Farber Cancer Institute

NCT00131014

RECRUITING Phase 1 940 participants

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Hoffmann-La Roche

NCT03075696

RECRUITING Phase 2 490 participants

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Merck Sharp & Dohme

NCT04728893

RECRUITING Phase 1 165 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma

AbbVie

NCT06667687

RECRUITING Phase 1 150 participants

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

AbbVie

NCT05618028

RECRUITING Phase 1 136 participants

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

Baylor College of Medicine

NCT01555892

RECRUITING Phase 2 132 participants

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

National Cancer Institute (NCI)

NCT04002947

RECRUITING Phase 2 78 participants

A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL

Ascentage Pharma Group

NCT04496349

RECRUITING Phase 2 54 participants

Cord Blood Transplant in Adults With Blood Cancers

Memorial Sloan Kettering Cancer Center

NCT05884333

RECRUITING Phase 1 21 participants

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Estrella Biopharma

NCT06343311

ACTIVE NOT RECRUITING Phase 3 165 participants

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

AbbVie

NCT03844048

ACTIVE NOT RECRUITING Phase 2 82 participants

Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Memorial Sloan Kettering Cancer Center

NCT01746849

ACTIVE NOT RECRUITING Phase 1 68 participants

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Baylor College of Medicine

NCT00840853

ACTIVE NOT RECRUITING Early Phase 1 63 participants

PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study

Memorial Sloan Kettering Cancer Center

NCT01269593

ACTIVE NOT RECRUITING Phase 2 33 participants

Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma

National Cancer Institute (NCI)

NCT03789240

ACTIVE NOT RECRUITING Phase 2 30 participants

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT03198026

ACTIVE NOT RECRUITING Phase 1 18 participants

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma

Baylor College of Medicine

NCT01192464

ACTIVE NOT RECRUITING Phase 1 17 participants

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

Memorial Sloan Kettering Cancer Center

NCT01840566

ACTIVE NOT RECRUITING Phase 1 10 participants

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Baylor College of Medicine

NCT00710892

ACTIVE NOT RECRUITING Phase 1 7 participants

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)

Baylor College of Medicine

NCT02050347

ACTIVE NOT RECRUITING Phase 1 6 participants

Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)

Sana Biotechnology

NCT06285422

COMPLETED 2,378 participants

Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma

National Cancer Institute (NCI)

NCT00341952

COMPLETED Phase 3 676 participants

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Millennium Pharmaceuticals

NCT00312845

COMPLETED Phase 3 447 participants

Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With R-CVP or R-CHOP in the First-Line Treatment of Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) - Referred to as the BRIGHT Study

Teva Branded Pharmaceutical Products R&D

NCT00877006

COMPLETED Phase 1 320 participants

An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma

Bristol-Myers Squibb

NCT01592370

COMPLETED Phase 2 264 participants

Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant

David Rizzieri, MD

NCT00597714

COMPLETED Phase 2 175 participants

GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma

Hoffmann-La Roche

NCT00576758

COMPLETED Phase 1 160 participants

Ublituximab in Combination With TGR-1202 +/- Ibrutinib or Bendamustine in Patients With B-cell Malignancies

TG Therapeutics

NCT02006485

COMPLETED Phase 3 135 participants

Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss

M.D. Anderson Cancer Center

NCT00352846

COMPLETED Phase 1 133 participants

A Study of Obinutuzumab, Rituximab, Polatuzumab Vedotin, and Venetoclax in Relapsed or Refractory Follicular Lymphoma (FL) or Diffuse Large B-Cell Lymphoma (DLBCL)

Hoffmann-La Roche

NCT02611323

COMPLETED Phase 2 96 participants

Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor

Memorial Sloan Kettering Cancer Center

NCT00582933

COMPLETED Phase 1 82 participants

Study of hA20 (Humanized Anti-CD20) in Patients With CD20+ Non-Hodgkin's Lymphoma

Gilead Sciences

NCT00285428

COMPLETED Phase 2 75 participants

Amifostine for Head and Neck Irradiation in Lymphoma

Dana-Farber Cancer Institute

NCT00136474

COMPLETED Phase 1 66 participants

A Study of Escalating Doses of DCDS0780A in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma

Hoffmann-La Roche

NCT02453087

COMPLETED Phase 3 54 participants

Study to Assess the Effect of Treatment With Bendamustine in Combination With Rituximab on QT Interval in Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL)

Cephalon

NCT01073163

COMPLETED Phase 2 49 participants

A Randomized Study of EPOCH II Versus EPOCH II and Immunotherapy in Lymphomas

National Cancer Institute (NCI)

NCT00001430

COMPLETED 48 participants

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Duke University

NCT01904175

COMPLETED Phase 2 46 participants

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Baylor College of Medicine

NCT00368355

COMPLETED Phase 2 43 participants

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

Celgene

NCT00179673

COMPLETED Phase 1 42 participants

VELCADE®-BEAM and Autologous Hematopoietic Stem Cell Transplantation for Non-Hodgkin's Lymphoma, or Mantle Cell Lymphoma

University of Nebraska

NCT00571493

COMPLETED Phase 2 40 participants

Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma

University of Wisconsin, Madison

NCT01281917

COMPLETED Phase 1 39 participants

Study of the Efficacy and Safety of Ublituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

TG Therapeutics

NCT01647971

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francisco

NCT00516152

COMPLETED Phase 1 35 participants

A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma

Amgen

NCT02961881

COMPLETED Phase 2 33 participants

Reduced Intensity Double Umbilical Cord Blood Transplantation

Massachusetts General Hospital

NCT01408563

COMPLETED Phase 2 32 participants

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

Massachusetts General Hospital

NCT00133367

COMPLETED Phase 2 31 participants

Meloxicam vs Placebo for Mobilization

Massachusetts General Hospital

NCT02003625

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

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Phase Distribution

PhaseTrial count
Phase 1 27
Phase 2 27
Phase 3 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Non-Hodgkin's Lymphoma Trial Landscape

64 indexed Non-Hodgkin's Lymphoma studies · 12 recruiting (19%).

Phase mix: 5 late (III/IV) vs 54 early (I/II).

Top sponsor: Baylor College of Medicine (6 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Non-Hodgkin's Lymphoma?

PlainTrial tracks 64 US clinical trials for Non-Hodgkin's Lymphoma, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Non-Hodgkin's Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.