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RECRUITING Phase 2

Growth Hormone Replacement Therapy for Retried Professional Football Players

NCT04121780 · View on ClinicalTrials.gov ↗

Study Summary

This is a randomized, double-blind, placebo-controlled, parallel-group trial with an open-label extension to evaluate the efficacy of growth hormone (GH) on cognitive functions of retired professional football players with growth hormone deficiency (GHD).

Interventions

  • OTHER Placebo
  • BIOLOGICAL Growth Hormone

Study Locations (1)

Michigan

  • Center for Neurolgoical Studies (CNS) — Dearborn

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2019-10-08
Est. Completion 2026-09
Phase Phase 2

Sponsor

Center for Neurological Studies

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04121780

The ClinicalTrials.gov registry entry for NCT04121780 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Center for Neurological Studies, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Concussion, Brain appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04121780 reports 1 study location spanning 1 distinct geographic area — top geographies include Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04121780 about?

NCT04121780 is a clinical study titled "Growth Hormone Replacement Therapy for Retried Professional Football Players". This is a randomized, double-blind, placebo-controlled, parallel-group trial with an open-label extension to evaluate the efficacy of growth hormone (GH) on cognitive functions of retired professional football players with growth hormone deficiency (GHD).

What is the current status of trial NCT04121780?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2019-10-08. Estimated completion is 2026-09.

What conditions does trial NCT04121780 study?

This clinical trial studies the following conditions: Concussion, Brain, TBI (Traumatic Brain Injury), Growth Hormone Deficiency, Hypopituitarism, Sport Injury. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04121780?

The interventions under investigation include: Placebo (OTHER), Growth Hormone (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04121780?

This trial is sponsored by Center for Neurological Studies, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04121780 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial