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ClinicalTrials.gov 46 recruiting now early-phase tilt #122 of 28,707 conditions

Cognitive Impairment: early-phase trial registry

46 of 106 indexed Cognitive Impairment trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #122 of 28,707 conditions by registered trial count.

106 US clinical trials · 46 currently recruiting · #122 of 28,707 conditions by registered trial count

Cognitive Impairment: 106 US clinical trials tracked, 46 recruiting.

Cognitive Impairment is the subject of 106 registered US clinical trials on ClinicalTrials.gov, 46 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Alabama at Birmingham, running 7 of these trials.

Enrollment posture brief

Registry condition cognitive-impairment

OPEN 46 | RECR 43% | LATE 6 | EARLY 12 | RANK #122 | SPON 7

Nearest open-share peer: Healthy Volunteer (43% recruiting · 113 trials)

Breast Carcinoma58.9%Non-Hodgkin Lymphoma54.2%Opioid Use43.4%Cognitive Impairment (this)43%Crohn's Disease34.9%
Open-enrollment share among volume-matched conditions near Cognitive Impairment

Cognitive Impairment lists 46 open slots (43% of 106 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cognitive Impairment on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cognitive Impairment is recruiting above its size-band peers.

    46 of 106 indexed trials (43.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cognitive Impairment trials is spread across many organizations.

    University of Alabama at Birmingham accounts for 7 of 106 trials (6.6%). 63 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cognitive Impairment enrolment sits around 83 participants.

    Median target enrolment is 83 among the 106 trials that report a genuine target (sentinel values excluded). 62 of those (58.5%) plan for fewer than 100 participants.

  4. Cognitive Impairment research is mostly interventional.

    84 interventional and 22 observational studies make up this index (79.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 210Phase 34Phase 42

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 10
Phase 3 4
Phase 4 2

Named interventions

Most-linked intervention names on Cognitive Impairment records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
RACS app Behavioral
2 trials
game-like computerized activities Behavioral
2 trials
Memantine Drug
2 trials
Anticipating Decline and Providing Therapy (ADAPT) Behavioral
1 trials
Usual Care post-Intensive Care Unit (ICU) Behavioral
1 trials
Enhanced psycho-education about dementia and caregiving Behavioral
1 trials
Supportive therapy (time and attention control) Behavioral
1 trials

US sites by state

Facility locations filed on Cognitive Impairment trials. A trial with sites in several states counts in each.

California 20 trials
New York 12 trials
Florida 9 trials
Alabama 9 trials
Texas 8 trials
North Carolina 8 trials
Massachusetts 8 trials
Illinois 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cognitive Impairment page

106 registered trials, 46 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cognitive Impairment condition card totals 106 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.