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Carcinoma, Non-Small Cell Lung clinical trials
43 of 133 indexed Carcinoma, Non-Small Cell Lung trials are currently recruiting.
133 US clinical trials · 43 currently recruiting
Carcinoma, Non-Small Cell Lung is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 43 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 14 of these trials.
The research picture
Carcinoma, Non-Small Cell Lung has 133 registered US clinical trials, 43 of them open to new participants right now, about 32% of the total.
- 43
- recruiting participants now
- 32%
- of trials open to enrollment
- 27
- in Phase 3–4 (later-stage)
- 14
- top sponsor: Pfizer
Active & Recent Trials
133 total, page 3 of 3
Multimodality Treatment for Patients With Resectable Non-Small Cell Lung Cancer (NSCLC) - BEACON Study: Bevacizumab and Chemotherapy for Operable NSCLC
Memorial Sloan Kettering Cancer Center
NCT00130780
Gemcitabine/Platinum Containing Regimens as Preoperative Chemotherapy for Patients With Non Small Cell Lung Cancer
Eli Lilly and Company
NCT00191230
Safety/Efficacy Study of Immunoconjugate With Docetaxel in Non-small Cell Lung Carcinoma
Seagen
NCT00051571
MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC).
MedImmune
NCT02088112
Study of Paclitaxel, Carboplatin, and Cetuximab for Advanced Lung Cancer
Fox Chase Cancer Center
NCT00315185
ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.
Eli Lilly and Company
NCT00051493
Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT00001499
AMG 102 and Erlotinib for Advanced Non-Small Cell Lung Cancer
Ahmad Tarhini
NCT01233687
Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00063219
Healthy Directions After Lung Surgery Pilot
Dana-Farber Cancer Institute
NCT02135211
Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib
Kadmon Corporation
NCT00522145
A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies
Bristol-Myers Squibb
NCT00441337
A Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung Cancer
BioNTech US
NCT03380871
A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...
National Cancer Institute (NCI)
NCT00923481
A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations
Boehringer Ingelheim
NCT01647711
Combination of Weekly Chest Radiotherapy and Oral Navelbine for the Palliation of Advanced Non Small Cell Lung Cancer: A Phase I Study
Clinical Oncology Research Associates
NCT00256815
Trial of Weekly Taxotere and Irinotecan (CPT-11) in Patients With Advanced Non-small Cell Lung Cancer
Sanofi
NCT00819728
Natural Killer Cells and Bortezomib to Treat Cancer
National Heart, Lung, and Blood Institute (NHLBI)
NCT00720785
A Study to Examine Biomarkers From Lung and Blood Samples in Participants With Suspected Lung Cancer
Janssen Research & Development
NCT04951154
PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)
Pfizer
NCT00043368
Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT02897778
Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT02909452
G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer
G1 Therapeutics
NCT03455829
Once Weekly Radiation for Lung Cancer With Chemotherapy
Clinical Oncology Research Associates
NCT00256789
Hypofractionated Proton Beam Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Stage II-III Non-Small Cell Lung Cancer
Washington University School of Medicine
NCT02172846
BIO 300 Non-Small Cell Lung Cancer Study
Humanetics Corporation
NCT02567799
A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors
Cantargia AB
NCT04452214
Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer
Novartis Pharmaceuticals
NCT03647488
Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
Stanford University
NCT00946673
ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer
Active Biotech AB
NCT00132379
Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors
Nagla Abdel Karim
NCT03023319
Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)
Pfizer
NCT00034957
A Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based Chemotherapy
R-Pharm
NCT00035516
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 58 |
| Phase 2 | 34 |
| Phase 3 | 27 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Carcinoma, Non-Small Cell Lung Trial Landscape
133 indexed Carcinoma, Non-Small Cell Lung studies · 43 recruiting (32%).
Phase mix: 27 late (III/IV) vs 92 early (I/II).
Top sponsor: Pfizer (14 trials), 9 others listed. 33 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Carcinoma, Non-Small Cell Lung?
PlainTrial tracks 133 US clinical trials for Carcinoma, Non-Small Cell Lung, of which 43 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Carcinoma, Non-Small Cell Lung?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.