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ClinicalTrials.gov 43 recruiting now official registry

Carcinoma, Non-Small Cell Lung clinical trials

43 of 133 indexed Carcinoma, Non-Small Cell Lung trials are currently recruiting.

133 US clinical trials · 43 currently recruiting

Carcinoma, Non-Small Cell Lung is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 43 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 14 of these trials.

The research picture

Carcinoma, Non-Small Cell Lung has 133 registered US clinical trials, 43 of them open to new participants right now, about 32% of the total.

43
recruiting participants now
32%
of trials open to enrollment
27
in Phase 3–4 (later-stage)
14
top sponsor: Pfizer
Phase 158Phase 234Phase 327

Active & Recent Trials

133 total, page 3 of 3

COMPLETED Phase 2 71 participants

Multimodality Treatment for Patients With Resectable Non-Small Cell Lung Cancer (NSCLC) - BEACON Study: Bevacizumab and Chemotherapy for Operable NSCLC

Memorial Sloan Kettering Cancer Center

NCT00130780

COMPLETED Phase 2 70 participants

Gemcitabine/Platinum Containing Regimens as Preoperative Chemotherapy for Patients With Non Small Cell Lung Cancer

Eli Lilly and Company

NCT00191230

COMPLETED Phase 2 60 participants

Safety/Efficacy Study of Immunoconjugate With Docetaxel in Non-small Cell Lung Carcinoma

Seagen

NCT00051571

COMPLETED Phase 1 56 participants

MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC).

MedImmune

NCT02088112

COMPLETED Phase 2 53 participants

Study of Paclitaxel, Carboplatin, and Cetuximab for Advanced Lung Cancer

Fox Chase Cancer Center

NCT00315185

COMPLETED Phase 2 50 participants

ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.

Eli Lilly and Company

NCT00051493

COMPLETED Phase 2 50 participants

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00001499

COMPLETED Phase 1 49 participants

AMG 102 and Erlotinib for Advanced Non-Small Cell Lung Cancer

Ahmad Tarhini

NCT01233687

COMPLETED Phase 2 48 participants

Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00063219

COMPLETED NA 42 participants

Healthy Directions After Lung Surgery Pilot

Dana-Farber Cancer Institute

NCT02135211

COMPLETED Phase 2 41 participants

Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib

Kadmon Corporation

NCT00522145

COMPLETED Phase 1 39 participants

A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies

Bristol-Myers Squibb

NCT00441337

COMPLETED Phase 1 38 participants

A Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung Cancer

BioNTech US

NCT03380871

COMPLETED Phase 2 37 participants

A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...

National Cancer Institute (NCI)

NCT00923481

COMPLETED Phase 1 35 participants

A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations

Boehringer Ingelheim

NCT01647711

COMPLETED Phase 1 35 participants

Combination of Weekly Chest Radiotherapy and Oral Navelbine for the Palliation of Advanced Non Small Cell Lung Cancer: A Phase I Study

Clinical Oncology Research Associates

NCT00256815

COMPLETED Phase 2 35 participants

Trial of Weekly Taxotere and Irinotecan (CPT-11) in Patients With Advanced Non-small Cell Lung Cancer

Sanofi

NCT00819728

COMPLETED Phase 1 35 participants

Natural Killer Cells and Bortezomib to Treat Cancer

National Heart, Lung, and Blood Institute (NHLBI)

NCT00720785

COMPLETED 33 participants

A Study to Examine Biomarkers From Lung and Blood Samples in Participants With Suspected Lung Cancer

Janssen Research & Development

NCT04951154

COMPLETED Phase 2 31 participants

PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)

Pfizer

NCT00043368

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 1 30 participants

G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer

G1 Therapeutics

NCT03455829

COMPLETED NA 26 participants

Once Weekly Radiation for Lung Cancer With Chemotherapy

Clinical Oncology Research Associates

NCT00256789

COMPLETED Phase 1 23 participants

Hypofractionated Proton Beam Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Stage II-III Non-Small Cell Lung Cancer

Washington University School of Medicine

NCT02172846

COMPLETED Phase 1 21 participants

BIO 300 Non-Small Cell Lung Cancer Study

Humanetics Corporation

NCT02567799

COMPLETED Phase 1 19 participants

A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors

Cantargia AB

NCT04452214

COMPLETED Phase 2 18 participants

Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer

Novartis Pharmaceuticals

NCT03647488

COMPLETED Phase 1 17 participants

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Stanford University

NCT00946673

COMPLETED Phase 1 13 participants

ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer

Active Biotech AB

NCT00132379

COMPLETED Phase 1 6 participants

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Nagla Abdel Karim

NCT03023319

COMPLETED Phase 2

Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)

Pfizer

NCT00034957

COMPLETED Phase 2

A Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based Chemotherapy

R-Pharm

NCT00035516

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Phase Distribution

PhaseTrial count
Phase 1 58
Phase 2 34
Phase 3 27

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Carcinoma, Non-Small Cell Lung Trial Landscape

133 indexed Carcinoma, Non-Small Cell Lung studies · 43 recruiting (32%).

Phase mix: 27 late (III/IV) vs 92 early (I/II).

Top sponsor: Pfizer (14 trials), 9 others listed. 33 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Carcinoma, Non-Small Cell Lung?

PlainTrial tracks 133 US clinical trials for Carcinoma, Non-Small Cell Lung, of which 43 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Carcinoma, Non-Small Cell Lung?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.