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ClinicalTrials.gov 43 recruiting now early-phase tilt #86 of 28,707 conditions

Carcinoma, Non-Small Cell Lung: early-phase trial registry

43 of 133 indexed Carcinoma, Non-Small Cell Lung trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #86 of 28,707 conditions by registered trial count.

133 US clinical trials · 43 currently recruiting · #86 of 28,707 conditions by registered trial count

Carcinoma, Non-Small Cell Lung: 133 US clinical trials tracked, 43 recruiting.

Carcinoma, Non-Small Cell Lung is the subject of 133 registered US clinical trials on ClinicalTrials.gov, 43 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 14 of these trials.

Enrollment posture brief

Registry condition carcinoma-non-small-cell-lung

OPEN 43 | RECR 32% | LATE 27 | EARLY 92 | RANK #86 | SPON 14

Nearest open-share peer: Anatomic Stage IIIB Breast Cancer AJCC v8 (32% recruiting · 34 trials)

Esophageal Cancer47.7%Acute Lymphoblastic Leukemia43.9%Inflammation38.3%Physical Activity34.1%Carcinoma, Non-Small Cel (th…32%
Open-enrollment share among volume-matched conditions near Carcinoma, Non-Small Cell Lung

Carcinoma, Non-Small Cell Lung lists 43 open slots (32% of 133 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Carcinoma, Non-Small Cell Lung on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Carcinoma, Non-Small Cell Lung is recruiting below its size-band peers.

    43 of 133 indexed trials (32.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Carcinoma, Non-Small Cell Lung trials is spread across many organizations.

    Pfizer accounts for 14 of 133 trials (10.5%). 59 distinct sponsors appear on at least one study for this condition label.

  3. Typical Carcinoma, Non-Small Cell Lung enrolment sits around 126 participants.

    Median target enrolment is 126 among the 131 trials that report a genuine target (sentinel values excluded). 58 of those (44.3%) plan for fewer than 100 participants.

  4. Carcinoma, Non-Small Cell Lung research is mostly interventional.

    123 interventional and 10 observational studies make up this index (92.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 158Phase 234Phase 327

Open and recent trials

133 total, page 3 of 3

COMPLETED Phase 2 71 participants

Multimodality Treatment for Patients With Resectable Non-Small Cell Lung Cancer (NSCLC) - BEACON Study: Bevacizumab and Chemotherapy for Operable NSCLC

Memorial Sloan Kettering Cancer Center

NCT00130780

COMPLETED Phase 2 70 participants

Gemcitabine/Platinum Containing Regimens as Preoperative Chemotherapy for Patients With Non Small Cell Lung Cancer

Eli Lilly and Company

NCT00191230

COMPLETED Phase 2 60 participants

Safety/Efficacy Study of Immunoconjugate With Docetaxel in Non-small Cell Lung Carcinoma

Seagen

NCT00051571

COMPLETED Phase 1 56 participants

MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC).

MedImmune

NCT02088112

COMPLETED Phase 2 53 participants

Study of Paclitaxel, Carboplatin, and Cetuximab for Advanced Lung Cancer

Fox Chase Cancer Center

NCT00315185

COMPLETED Phase 2 50 participants

ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.

Eli Lilly and Company

NCT00051493

COMPLETED Phase 2 50 participants

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00001499

COMPLETED Phase 1 49 participants

AMG 102 and Erlotinib for Advanced Non-Small Cell Lung Cancer

Ahmad Tarhini

NCT01233687

COMPLETED Phase 2 48 participants

Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00063219

COMPLETED NA 42 participants

Healthy Directions After Lung Surgery Pilot

Dana-Farber Cancer Institute

NCT02135211

COMPLETED Phase 2 41 participants

Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib

Kadmon Corporation

NCT00522145

COMPLETED Phase 1 39 participants

A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies

Bristol-Myers Squibb

NCT00441337

COMPLETED Phase 1 38 participants

A Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung Cancer

BioNTech US

NCT03380871

COMPLETED Phase 2 37 participants

A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...

National Cancer Institute (NCI)

NCT00923481

COMPLETED Phase 1 35 participants

A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations

Boehringer Ingelheim

NCT01647711

COMPLETED Phase 1 35 participants

Combination of Weekly Chest Radiotherapy and Oral Navelbine for the Palliation of Advanced Non Small Cell Lung Cancer: A Phase I Study

Clinical Oncology Research Associates

NCT00256815

COMPLETED Phase 2 35 participants

Trial of Weekly Taxotere and Irinotecan (CPT-11) in Patients With Advanced Non-small Cell Lung Cancer

Sanofi

NCT00819728

COMPLETED Phase 1 35 participants

Natural Killer Cells and Bortezomib to Treat Cancer

National Heart, Lung, and Blood Institute (NHLBI)

NCT00720785

COMPLETED 33 participants

A Study to Examine Biomarkers From Lung and Blood Samples in Participants With Suspected Lung Cancer

Janssen Research & Development

NCT04951154

COMPLETED Phase 2 31 participants

PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)

Pfizer

NCT00043368

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 1 30 participants

G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer

G1 Therapeutics

NCT03455829

COMPLETED NA 26 participants

Once Weekly Radiation for Lung Cancer With Chemotherapy

Clinical Oncology Research Associates

NCT00256789

COMPLETED Phase 1 23 participants

Hypofractionated Proton Beam Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Stage II-III Non-Small Cell Lung Cancer

Washington University School of Medicine

NCT02172846

COMPLETED Phase 1 21 participants

BIO 300 Non-Small Cell Lung Cancer Study

Humanetics Corporation

NCT02567799

COMPLETED Phase 1 19 participants

A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors

Cantargia AB

NCT04452214

COMPLETED Phase 2 18 participants

Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer

Novartis Pharmaceuticals

NCT03647488

COMPLETED Phase 1 17 participants

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Stanford University

NCT00946673

COMPLETED Phase 1 13 participants

ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer

Active Biotech AB

NCT00132379

COMPLETED Phase 1 6 participants

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Nagla Abdel Karim

NCT03023319

COMPLETED Phase 2

Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)

Pfizer

NCT00034957

COMPLETED Phase 2

A Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based Chemotherapy

R-Pharm

NCT00035516

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Phase Distribution

PhaseTrial count
Phase 1 58
Phase 2 34
Phase 3 27

Named interventions

Most-linked intervention names on Carcinoma, Non-Small Cell Lung records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Carboplatin Drug
20 trials
Pemetrexed Drug
17 trials
Amivantamab Drug
11 trials
Placebo Drug
8 trials
Pembrolizumab Drug
8 trials
Pembrolizumab Biological
8 trials
Lazertinib Drug
7 trials
Paclitaxel Drug
7 trials

US sites by state

Facility locations filed on Carcinoma, Non-Small Cell Lung trials. A trial with sites in several states counts in each.

California 69 trials
Florida 50 trials
Texas 42 trials
New York 41 trials
Massachusetts 38 trials
Maryland 29 trials
Illinois 28 trials
Colorado 26 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Carcinoma, Non-Small Cell Lung page

133 registered trials, 43 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 43 Carcinoma, Non-Small Cell Lung trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Pfizer sponsors the most Carcinoma, Non-Small Cell Lung trials on record, review their full trial history before evaluating a specific study. See Pfizer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Carcinoma, Non-Small Cell Lung condition card totals 133 registered trials; most-linked intervention Carboplatin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.