Syndax Pharmaceuticals

25 total trials 2 currently recruiting 18 completed

Syndax Pharmaceuticals sponsors 25 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 18 completed. 0 of these trials are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Carcinoma, Non-Small Cell Lung, with 3 trials.

Trial Pipeline

25 total, page 1 of 1

RECRUITING Phase 1

A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

NCT06226571

RECRUITING Phase 1

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

NCT04065399

ACTIVE NOT RECRUITING Phase 2

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

NCT04710576

COMPLETED Phase 1

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

NCT05731947

COMPLETED Phase 1

Study of Radiolabeled Revumenib in Adults With Acute Leukemia

NCT05406817

COMPLETED Phase 1

A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

NCT05326516

TERMINATED Phase 2

A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19

NCT04415073

COMPLETED Phase 1

A Phase 1/2 Study to Evaluate Axatilimab in Participants With Active cGVHD

NCT03604692

COMPLETED Phase 1

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

NCT03238027

COMPLETED Phase 1

A Study to Evaluate the Pharmacokinetics of Entinostat in Adult Subjects With Normal and Impaired Renal Function

NCT03192111

COMPLETED Phase 1

A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects

NCT03187015

COMPLETED Phase 1

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

NCT02915523

COMPLETED Phase 1

A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

NCT02922933

COMPLETED Phase 1

Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat

NCT02922946

COMPLETED Phase 1

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

NCT02909452

COMPLETED Phase 1

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

NCT02897778

COMPLETED Phase 1

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

NCT02820961

COMPLETED Phase 1

Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In

NCT02708680

COMPLETED Phase 1

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

NCT02437136

COMPLETED Phase 1

Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer

NCT01594398

TERMINATED Phase 2

A Phase 2 Multi-Center Study of Entinostat (SNDX-275) in Patient With Relapsed or Refractory Hodgkin's Lymphoma

NCT00866333

TERMINATED Phase 2

A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib

NCT00750698

COMPLETED Phase 2

Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer

NCT00676663

TERMINATED Phase 1

A Phase I, Multicenter, Open Label Study on the Effects of SNDX-275 on Expression of Biomarkers in Subjects With Newly Diagnosed Breast Cancer

NCT00754312

COMPLETED Phase 1

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

NCT00602030

What the Pipeline for Syndax Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Syndax Pharmaceuticals is linked to 25 US clinical trials across every stage of research activity. Of those, 2 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 18 are already marked complete, representing roughly 72% of the total.

The phase mix for Syndax Pharmaceuticals reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 25 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Syndax Pharmaceuticals is Carcinoma, Non-Small Cell Lung with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.