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NCT02897778 · ClinicalTrials.gov registry record · Phase 1

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

A Phase 1 study of Neoplasms and Carcinoma, Non-Small Cell Lung, sponsored by Syndax Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT02897778 is a Phase 1 study of Neoplasms and Carcinoma, Non-Small Cell Lung that has completed, run by Syndax Pharmaceuticals. The registered enrollment target is 30 participants, below the 1,621-participant average among 158 other Neoplasms trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02897778, a Phase 1 study of Neoplasms and Carcinoma, Non-Small Cell Lung, has completed, sponsored by Syndax Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the effect of entinostat on heart rate and other electrocardiogram (ECG) parameters. This study will also evaluate the safety and tolerability of entinostat, as well as pharmacokinetic and pharmacodynamic parameters.

Interventions

  • DRUG Placebo
  • DRUG Entinostat

Study Locations (1)

Texas

  • The START Center for Cancer Care - San Antonio

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2016-08-24
Est. Completion 2017-03-13
Phase Phase 1

Sponsor

Syndax Pharmaceuticals

25 total trials

What the Registry Record Tells You About NCT02897778

The ClinicalTrials.gov registry entry for NCT02897778 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,621-participant average among 158 other Neoplasms trials with a reported enrollment target (98% lower). The listed sponsor is Syndax Pharmaceuticals, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Neoplasms appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02897778 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT02897778 about?

NCT02897778 is a clinical study titled "Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors". The purpose of this study is to evaluate the effect of entinostat on heart rate and other electrocardiogram (ECG) parameters. This study will also evaluate the safety and tolerability of entinostat, as well as pharmacokinetic and pharmacodynamic parameters.

What is the current status of trial NCT02897778?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2016-08-24. Estimated completion is 2017-03-13.

What conditions does trial NCT02897778 study?

This clinical trial studies the following conditions: Neoplasms, Carcinoma, Non-Small Cell Lung, Lung Neoplasms, Neoplasms by Histologic Type, Thoracic Neoplasms.

What interventions are being tested in trial NCT02897778?

The interventions under investigation include: Placebo (DRUG), Entinostat (DRUG).

Who is sponsoring clinical trial NCT02897778?

This trial is sponsored by Syndax Pharmaceuticals, which has 25 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02897778 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.