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NCT06446479 · ClinicalTrials.gov registry record · Phase 2

Effects of THC on Alcohol Consumption and Neural Correlates of Reward

A Phase 2 study of Cannabis Use Disorder, sponsored by University of Colorado, Denver.

Recruiting
Registry status
Phase 2
Development phase
28
Enrollment target
1
Study location

NCT06446479 is a Phase 2 study of Cannabis Use Disorder that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 28 participants, below the 108-participant average among 34 other Cannabis Use Disorder trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06446479, a Phase 2 study of Cannabis Use Disorder, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
Phase 2
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.

Conditions Studied

Cannabis Use Disorder

Interventions

  • DRUG Placebo
  • DRUG Dronabinol Pill

Study Locations (1)

Colorado

  • University of Colorado Anschutz Medical Campus - Aurora

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2024-07-01
Est. Completion 2026-06-30
Phase Phase 2

Sponsor

University of Colorado, Denver

1,283 total trials

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What the Registry Record Tells You About NCT06446479

The ClinicalTrials.gov registry entry for NCT06446479 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 108-participant average among 34 other Cannabis Use Disorder trials with a reported enrollment target (74% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cannabis Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06446479 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT06446479 about?

NCT06446479 is a clinical study titled "Effects of THC on Alcohol Consumption and Neural Correlates of Reward". Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption pattern...

What is the current status of trial NCT06446479?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 28 participants. The study started on 2024-07-01. Estimated completion is 2026-06-30.

What conditions does trial NCT06446479 study?

This clinical trial studies the following conditions: Cannabis Use Disorder.

What interventions are being tested in trial NCT06446479?

The interventions under investigation include: Placebo (DRUG), Dronabinol Pill (DRUG).

Who is sponsoring clinical trial NCT06446479?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06446479 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.