Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06085222 · ClinicalTrials.gov registry record · NA
Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
A NA study of Cannabis Use Disorder, sponsored by Florida State University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06085222: Recruiting NA study of Cannabis Use Disorder, sponsored by Florida State University.
NCT06085222 is a NA study of Cannabis Use Disorder that is actively recruiting participants, run by Florida State University. The registered enrollment target is 80 participants, below the 107-participant average among 34 other Cannabis Use Disorder trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06085222, a NA study of Cannabis Use Disorder, is actively recruiting participants, sponsored by Florida State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The prevalence of daily cannabis use and Cannabis Use Disorder (CUD) has increased in the United States over the past two decades. Brief, computerized harm reduction interventions that target specific high-risk CUD populations could be an efficient approach to reducing CUD. Distress intolerance , which refers to the tendency to negatively appraise and escape aversive emotional states, is a risk factor associated with stress-related cannabis use motivation and CUD severity/chronicity. Thus, a brief, accessible, low-cost intervention that reduces distress intolerance in those with CUD and elevated distress intolerance could have a significant public health impact. This proposed project aims to optimize an existing two-session computerized distress tolerance intervention and test its impact on distress intolerance and cannabis use outcomes in a randomized controlled trial. Specifically, the intervention will be condensed to one-session, its active ingredient bolstered, and augmented with smart phone-delivered therapy reminders. After obtaining feedback on the modified Emotional Engagement Distress Tolerance Intervention in a small sample, the intervention's efficacy compared to a stringent, credible, time-matched health education control intervention will be tested in a randomized controlled trial in 80 cannabis users with CUD and high distress intolerance. Distress intolerance, cannabis use, and psychosocial functioning outcomes will be evaluated. As an exploratory aim, a wristworn device will be used to measure objective stress responding in the real-world during the intervention period. Our central hypothesis is that, compared to a control intervention, the Emotional Engagement Distress Tolerance Intervention will produce superior reductions distress intolerance, stress-related cannabis use motivation, disordered cannabis use, and psychosocial functioning.
Primary Outcome
acceptability/feasibility (credibility subscale range 3-27; expectancy item range 0%-100%; higher scores indicate better outcome)
Conditions Studied
Interventions
- BEHAVIORAL Emotional Engagement Distress Tolerance Intervention
- BEHAVIORAL Health Education Intervention
Study Locations (1)
Florida
- The BRAINS Lab at Florida State University - Tallahassee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-06-04 |
| Est. Completion | 2027-10-30 |
| Phase | NA |
What NCT06085222 shows while recruiting
NCT06085222 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 107-participant average among 34 other Cannabis Use Disorder trials with a reported enrollment target (25% lower).
The record links to 1 condition, with Cannabis Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Emotional Engagement Distress Tolerance Intervention is the first listed.
NCT06085222 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06085222 about?
NCT06085222 is a clinical study titled "Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users". The prevalence of daily cannabis use and Cannabis Use Disorder (CUD) has increased in the United States over the past two decades. Brief, computerized harm reduction interventions that target specific high-risk CUD populations could be an efficient approach to reducing CUD. Distress intolerance , wh...
What is the current status of trial NCT06085222?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-06-04. Estimated completion is 2027-10-30.
What conditions does trial NCT06085222 study?
This clinical trial studies the following conditions: Cannabis Use Disorder.
What interventions are being tested in trial NCT06085222?
The interventions under investigation include: Emotional Engagement Distress Tolerance Intervention (BEHAVIORAL), Health Education Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT06085222?
This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06085222 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cannabis Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06085222's enrollment target sits among peer trials
80 16th of 34 higher than 17 of 34 other Cannabis Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cannabis Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
RECRUITING · NA
-
Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)
RECRUITING · NA
-
The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV
RECRUITING · NA
-
A Brief Intervention for Cannabis Use
RECRUITING · NA
-
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
RECRUITING · NA
-
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01243931 · 80 participants · NA
Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
- NCT01659203 · 80 participants · Phase 1
Proton or Photon RT for Retroperitoneal Sarcomas
- NCT01803451 · 80 participants · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
- NCT01964859 · 80 participants · Phase 2
Feasibility Study for Fibroblast Autologous Skin Grafts
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI