Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 13 recruiting now early-phase tilt small index

Brain Metastases, Adult: early-phase trial registry

13 of 15 indexed Brain Metastases, Adult trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 13 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Brain Metastases, Adult: 15 US clinical trials tracked, 13 recruiting.

Brain Metastases, Adult is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Baptist Health South Florida, running 3 of these trials.

Enrollment posture brief

Registry condition brain-metastases-adult

OPEN 13 | RECR 87% | LATE 0 | EARLY 10 | RANK #1140 | SPON 3

Nearest open-share peer: Cystic Fibrosis (CF) (87% recruiting · 15 trials)

Brain Metastases, Adult (thi…87%Advanced Lung Non-Small Cell53.3%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Brain Metastases, Adult

Brain Metastases, Adult lists 13 open slots (87% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Brain Metastases, Adult on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Brain Metastases, Adult is recruiting above its size-band peers.

    13 of 15 indexed trials (86.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Brain Metastases, Adult research.

    Baptist Health South Florida accounts for 3 of 15 trials (20%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Brain Metastases, Adult trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 15 trials that report a genuine target (sentinel values excluded). 10 of those (66.7%) plan for fewer than 100 participants.

  4. Brain Metastases, Adult research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 24

Open and recent trials

15 total, page 1 of 1

RECRUITING 300 participants

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Duke University

NCT05480644

RECRUITING NA 244 participants

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

Wake Forest University Health Sciences

NCT05703269

RECRUITING Phase 2 150 participants

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

Ayal A. Aizer, MD

NCT07130786

RECRUITING Phase 1 134 participants

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Neonc Technologies

NCT06047379

RECRUITING 119 participants

Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment

Memorial Sloan Kettering Cancer Center

NCT05559853

RECRUITING Phase 2 62 participants

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Memorial Sloan Kettering Cancer Center

NCT05419076

RECRUITING Phase 2 60 participants

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases

Jona Hattangadi-Gluth

NCT04343157

RECRUITING Phase 2 60 participants

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Ayal A. Aizer, MD

NCT07132190

RECRUITING Phase 1 46 participants

18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery

Baptist Health South Florida

NCT06048094

RECRUITING Phase 1 46 participants

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Baptist Health South Florida

NCT05789589

RECRUITING Phase 1 41 participants

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Colette Shen

NCT04711824

RECRUITING NA 40 participants

Multi-disciplinary Care for Brain Metastases

University of Vermont Medical Center

NCT06280300

RECRUITING Phase 1 20 participants

Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery

Baptist Health South Florida

NCT04689048

ACTIVE NOT RECRUITING NA 20 participants

A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

NCT05341739

ACTIVE NOT RECRUITING Early Phase 1 11 participants

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

Memorial Sloan Kettering Cancer Center

NCT06209567

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 4

Named interventions

Most-linked intervention names on Brain Metastases, Adult records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

18F fluciclovine Drug
2 trials
Stereotactic Radiosurgery Radiation
2 trials
68Ga-PSMA-11 PET Scans Diagnostic test
1 trials
Pre-operative Stereotactic Radiosurgery Other
1 trials
fractionated stereotactic radiosurgery (FSRS) Radiation
1 trials
single fraction stereotactic radiosurgery (SSRS) Radiation
1 trials
Cerebrospinal fluid collection Procedure
1 trials
Levetiracetam (Keppra) Drug
1 trials

US sites by state

Facility locations filed on Brain Metastases, Adult trials. A trial with sites in several states counts in each.

New York 5 trials
Florida 4 trials
New Jersey 3 trials
North Carolina 3 trials
Massachusetts 2 trials
California 2 trials
Washington 1 trials
Vermont 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Brain Metastases, Adult page

15 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Brain Metastases, Adult condition card totals 15 registered trials; most-linked intervention 18F fluciclovine; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.