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Brain Metastases, Adult clinical trials
13 of 15 indexed Brain Metastases, Adult trials are currently recruiting.
15 US clinical trials · 13 currently recruiting
Brain Metastases, Adult is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Baptist Health South Florida, running 3 of these trials.
The research picture
Brain Metastases, Adult has 15 registered US clinical trials, 13 of them open to new participants right now, about 87% of the total.
- 13
- recruiting participants now
- 87%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Baptist Health South Florida
Active & Recent Trials
15 total, page 1 of 1
Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors
Duke University
NCT05480644
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
Wake Forest University Health Sciences
NCT05703269
Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases
Ayal A. Aizer, MD
NCT07130786
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Neonc Technologies
NCT06047379
Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment
Memorial Sloan Kettering Cancer Center
NCT05559853
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Memorial Sloan Kettering Cancer Center
NCT05419076
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
Jona Hattangadi-Gluth
NCT04343157
Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction
Ayal A. Aizer, MD
NCT07132190
18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery
Baptist Health South Florida
NCT06048094
Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases
Baptist Health South Florida
NCT05789589
Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases
Colette Shen
NCT04711824
Multi-disciplinary Care for Brain Metastases
University of Vermont Medical Center
NCT06280300
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
Baptist Health South Florida
NCT04689048
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
NCT05341739
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors
Memorial Sloan Kettering Cancer Center
NCT06209567
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Brain Metastases, Adult Trial Landscape
15 indexed Brain Metastases, Adult studies · 13 recruiting (87%).
Phase mix: 0 late (III/IV) vs 10 early (I/II).
Top sponsor: Baptist Health South Florida (3 trials), 9 others listed. 15 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Brain Metastases, Adult?
PlainTrial tracks 15 US clinical trials for Brain Metastases, Adult, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Brain Metastases, Adult?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.