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ClinicalTrials.gov 13 recruiting now full pipeline small index

Cystic Fibrosis (CF): full-pipeline trial registry

13 of 15 indexed Cystic Fibrosis (CF) trials are currently recruiting.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 13 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Cystic Fibrosis (CF): 15 US clinical trials tracked, 13 recruiting.

Cystic Fibrosis (CF) is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Indiana University, running 2 of these trials.

Enrollment posture brief

Registry condition cystic-fibrosis-cf

OPEN 13 | RECR 87% | LATE 2 | EARLY 3 | RANK #1140 | SPON 2

Nearest open-share peer: Brain Metastases, Adult (87% recruiting · 15 trials)

Cystic Fibrosis (this)87%Advanced Lung Non-Small Cell53.3%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Cystic Fibrosis (CF)

Cystic Fibrosis (CF) lists 13 open slots (87% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cystic Fibrosis (CF) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cystic Fibrosis (CF) is recruiting above its size-band peers.

    13 of 15 indexed trials (86.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cystic Fibrosis (CF) trials is spread across many organizations.

    Indiana University accounts for 2 of 15 trials (13.3%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Most Cystic Fibrosis (CF) trials plan to enrol fewer than 100 people.

    Median target enrolment is 70 among the 15 trials that report a genuine target (sentinel values excluded). 10 of those (66.7%) plan for fewer than 100 participants.

  4. Cystic Fibrosis (CF) splits between interventional and observational designs.

    10 interventional and 5 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 23Phase 31Phase 41

Open and recent trials

15 total, page 1 of 1

RECRUITING 600 participants

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

State University of New York at Buffalo

NCT07048574

RECRUITING 260 participants

Kidney Function in People With Cystic Fibrosis in the Era of HEMT

University of Virginia

NCT06595420

RECRUITING 220 participants

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

University of Florida

NCT01851642

RECRUITING 200 participants

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Jaeb Center for Health Research

NCT06837181

RECRUITING Phase 4 95 participants

Ensuring Access to Optimal Therapy in CF: The ENACT Study

Arkansas Children's Hospital Research Institute

NCT07148739

RECRUITING NA 80 participants

CF Wellness Program

Johns Hopkins University

NCT07071324

RECRUITING NA 70 participants

CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis

Indiana University

NCT06642610

RECRUITING Phase 3 64 participants

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy

Indiana University

NCT06996951

RECRUITING Phase 2 63 participants

Study With Phage for CF Subjects With Pseudomonas Lung Infection

BiomX

NCT06998043

RECRUITING NA 60 participants

ACT With CF Self-Help Toolkit

Thomas Jefferson University

NCT07436351

RECRUITING NA 60 participants

OnTrackCF: Engagement, Feasibility, and Acceptability Study

Boston Children's Hospital

NCT07031323

RECRUITING NA 30 participants

Personalized Mobile Health Platform to Promote Physical Activity in Adolescents and Young Adults With Cystic Fibrosis

Nemours Children's Clinic

NCT06616857

RECRUITING Phase 2 16 participants

Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

Sionna Therapeutics

NCT07108153

COMPLETED Phase 2 151 participants

Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients

Amgen

NCT00677365

COMPLETED 5 participants

: TRANSITION: An Observational Study of Transition From Lumacaftor/Ivacaftor to Tezacaftor/Ivacaftor (Tez/Iva)

National Jewish Health

NCT03445793

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Cystic Fibrosis (CF) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

MP-376 Drug
1 trials
OnTrackCF Behavioral
1 trials
CF Wellness Program Behavioral
1 trials
CGM Dynamic Index (CDI) Device
1 trials
Placebo-to-match SION-719 Drug
1 trials
SION-719 Drug
1 trials
therapeutic drug monitoring Other
1 trials
Elexacaftor / Ivacaftor / Tezacaftor Drug
1 trials

US sites by state

Facility locations filed on Cystic Fibrosis (CF) trials. A trial with sites in several states counts in each.

Massachusetts 6 trials
Florida 6 trials
Colorado 6 trials
Alabama 5 trials
New York 4 trials
California 4 trials
Washington 3 trials
Maryland 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cystic Fibrosis (CF) page

15 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 13 Cystic Fibrosis (CF) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Indiana University sponsors the most Cystic Fibrosis (CF) trials on record, review their full trial history before evaluating a specific study. See Indiana University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cystic Fibrosis (CF) condition card totals 15 registered trials; most-linked intervention MP-376; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.