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NCT05341739 · ClinicalTrials.gov registry record · NA
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases
A NA study of Brain Metastases, Adult, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05341739: Active NA study of Brain Metastases, Adult, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
NCT05341739 is a NA study of Brain Metastases, Adult that is active but no longer recruiting, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). The registered enrollment target is 20 participants, below the 95-participant average among 14 other Brain Metastases, Adult trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05341739, a NA study of Brain Metastases, Adult, is active but no longer recruiting, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a research study to determine if performing stereotactic radiosurgery (SRS) prior to surgical resection of the brain metastasis (tumor) will improve local control, in other words, increase the possibility of total removal of the primary tumor without local recurrence on longterm follow up. This research study will also determine if pre-operative SRS will lower the risk of radionecrosis that is the breakdown of body tissue at the original tumor site, and the development of leptomeningeal disease.
Primary Outcome
Radiographic local control at 1 year following completion of pre-operative SRS followed by surgical resection of brain metastasis. Local control will be according to the Response Assessment criteria for Neuro-Oncology (RANO) for brain metastases.
Conditions Studied
Interventions
- OTHER Pre-operative Stereotactic Radiosurgery
Study Locations (1)
Pennsylvania
- Allegheny General Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-12-14 |
| Est. Completion | 2025-11 |
| Phase | NA |
Sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)34 total trials
What the registry record for NCT05341739 still lists
NCT05341739 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 95-participant average among 14 other Brain Metastases, Adult trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Brain Metastases, Adult appearing as the primary indexed condition, and to 1 intervention - of which Pre-operative Stereotactic Radiosurgery is the first listed.
NCT05341739 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05341739 about?
NCT05341739 is a clinical study titled "A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases". This is a research study to determine if performing stereotactic radiosurgery (SRS) prior to surgical resection of the brain metastasis (tumor) will improve local control, in other words, increase the possibility of total removal of the primary tumor without local recurrence on longterm follow up. T...
What is the current status of trial NCT05341739?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2021-12-14. Estimated completion is 2025-11.
What conditions does trial NCT05341739 study?
This clinical trial studies the following conditions: Brain Metastases, Adult.
What interventions are being tested in trial NCT05341739?
The interventions under investigation include: Pre-operative Stereotactic Radiosurgery (OTHER).
Who is sponsoring clinical trial NCT05341739?
This trial is sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), which has 34 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05341739 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05341739's enrollment target sits among peer trials
20 13th of 14 higher than 1 of 14 other Brain Metastases, Adult trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Metastases, Adult trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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