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ClinicalTrials.gov 112 recruiting now early-phase tilt #41 of 28,707 conditions

Autism Spectrum Disorder: early-phase trial registry

112 of 225 indexed Autism Spectrum Disorder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #41 of 28,707 conditions by registered trial count.

225 US clinical trials · 112 currently recruiting · #41 of 28,707 conditions by registered trial count

Autism Spectrum Disorder: 225 US clinical trials tracked, 112 recruiting.

Autism Spectrum Disorder is the subject of 225 registered US clinical trials on ClinicalTrials.gov, 112 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 19 of these trials.

Enrollment posture brief

Registry condition autism-spectrum-disorder

OPEN 112 | RECR 50% | LATE 4 | EARLY 49 | RANK #41 | SPON 19

Nearest open-share peer: Alzheimer Disease (50% recruiting · 312 trials)

Autism Spectrum Disorder (th…50%Mild Cognitive Impairment48.5%Sickle Cell Disease44.4%Coronary Artery Disease25.9%Diabetes Mellitus23.3%
Open-enrollment share among volume-matched conditions near Autism Spectrum Disorder

Autism Spectrum Disorder lists 112 open slots (50% of 225 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Autism Spectrum Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Autism Spectrum Disorder is recruiting above its size-band peers.

    112 of 225 indexed trials (49.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Autism Spectrum Disorder trials is spread across many organizations.

    Stanford University accounts for 19 of 225 trials (8.4%). 113 distinct sponsors appear on at least one study for this condition label.

  3. Most Autism Spectrum Disorder trials plan to enrol fewer than 100 people.

    Median target enrolment is 67 among the 225 trials that report a genuine target (sentinel values excluded). 147 of those (65.3%) plan for fewer than 100 participants.

  4. Autism Spectrum Disorder research is mostly interventional.

    195 interventional and 30 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 237Phase 32Phase 42

Open and recent trials

225 total, page 3 of 5

RECRUITING 21 participants

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

Royal Devon and Exeter NHS Foundation Trust

NCT05751525

RECRUITING NA 20 participants

Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)

University of New Mexi

NCT06495684

RECRUITING NA 20 participants

Speech Treatment for Minimally Verbal Children With ASD and CAS

MGH Institute of Health Professions

NCT05066178

RECRUITING Phase 2 20 participants

A Phase 2A Trial of MM402 for Autism Spectrum Disorder

Definium Therapeutics US

NCT07303907

RECRUITING 19 participants

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT05600946

RECRUITING NA 15 participants

Novel Adaptive Cognitive Training in Autistic Adults with Co-occurring Insomnia

University of South Florida

NCT06291298

RECRUITING NA 12 participants

Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities

Christiana Care Health Services

NCT06807684

RECRUITING NA 10 participants

Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients

Boston Medical Center

NCT06712784

RECRUITING NA 10 participants

taVNS for Anxiety in ASD

Medical University of South Carolina

NCT06258590

RECRUITING NA 10 participants

Telehealth Intervention for Autism Spectrum Disorder

Thomas Jefferson University

NCT04832152

RECRUITING 10 participants

DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Icahn School of Medicine at Mount Sinai

NCT03718910

RECRUITING NA 8 participants

Milieu Teaching-AV (MT-AV Pilot)

Vanderbilt University Medical Center

NCT06794476

ACTIVE NOT RECRUITING NA 700 participants

Evaluating a Social and Communication Intervention for Preschoolers

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01591707

ACTIVE NOT RECRUITING 600 participants

Genome Environment Microbiome and Metabolome in Autism Study

Massachusetts General Hospital

NCT04271774

ACTIVE NOT RECRUITING 500 participants

Autism ALERT Expansion

Oregon Health and Science University

NCT06246890

ACTIVE NOT RECRUITING NA 360 participants

Trial of Autism Parent Navigator Program

Penn State University

NCT04744428

ACTIVE NOT RECRUITING NA 358 participants

AIRB-4: Self-Determined Learning Model of Instruction

Health Resources and Services Administration (HRSA)

NCT04972851

ACTIVE NOT RECRUITING NA 320 participants

Efficacy of the ASPEN Intervention Program in Low-Resource Communities

University of Texas at Austin

NCT04505488

ACTIVE NOT RECRUITING NA 308 participants

AIR-B4: Mind the Gap

Health Resources and Services Administration (HRSA)

NCT04972825

ACTIVE NOT RECRUITING 297 participants

Mitochondrial Dysfunction in Autism Spectrum Disorder

University of Arkansas

NCT02000284

ACTIVE NOT RECRUITING NA 264 participants

AIR-B4: Remaking Recess (RR)

Health Resources and Services Administration (HRSA)

NCT04972838

ACTIVE NOT RECRUITING 240 participants

Genetic Contributions to Autism Spectrum Disorders

Boston Children's Hospital

NCT01160783

ACTIVE NOT RECRUITING 205 participants

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Boston Children's Hospital

NCT02461420

ACTIVE NOT RECRUITING 201 participants

A Novel Framework for Impaired Imitation in ASD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT03423160

ACTIVE NOT RECRUITING NA 200 participants

Project AFECT (Autism Family Empowerment Coaching and Training Program)

Stanford University

NCT05910502

ACTIVE NOT RECRUITING Phase 2 150 participants

ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)

MapLight Therapeutics

NCT05081245

ACTIVE NOT RECRUITING NA 144 participants

DOD Regulating Together Intervention

Children's Hospital Medical Center, Cincinnati

NCT05803369

ACTIVE NOT RECRUITING NA 140 participants

PRISM Intervention Study

University of California, Los Angeles

NCT03883139

ACTIVE NOT RECRUITING NA 100 participants

Transcranial Magnetic Stimulation on Neural and Behavioral Facets of Social Cognition in Autism Spectrum Disorder

Yale University

NCT04242355

ACTIVE NOT RECRUITING NA 100 participants

RCT to Evaluate Social Skills in Children With Autism Using VR Technology (SoCaVR)

Floreo

NCT06453629

ACTIVE NOT RECRUITING Phase 2 86 participants

CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr

University of Colorado, Denver

NCT04520685

ACTIVE NOT RECRUITING NA 80 participants

Evaluating the Impact of Telehealth-Based ASD Assessments and Supports on Child and Caregiver Outcomes

University of California, Davis

NCT04881656

ACTIVE NOT RECRUITING NA 80 participants

Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism

University of Pennsylvania

NCT05373537

ACTIVE NOT RECRUITING NA 75 participants

Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition

Nova Southeastern University

NCT06269614

ACTIVE NOT RECRUITING NA 75 participants

A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism

Stanford University

NCT03778827

ACTIVE NOT RECRUITING NA 73 participants

Facing Your Fears: Adolescents With ASD and Intellectual Disability

University of Colorado, Denver

NCT05131425

ACTIVE NOT RECRUITING NA 65 participants

Behavior Therapy for Irritability in Autism

Yale University

NCT04654260

ACTIVE NOT RECRUITING NA 64 participants

Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD

Children's National Research Institute

NCT05131659

ACTIVE NOT RECRUITING Phase 2 60 participants

Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders

Gut-Brain-Axis Therapeutics

NCT06503978

ACTIVE NOT RECRUITING NA 56 participants

Developing a Culturally Adapted Intervention for Latino Youth Transitioning to Adulthood

The University of Texas Health Science Center, Houston

NCT06107972

ACTIVE NOT RECRUITING NA 56 participants

Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)

University of California, Los Angeles

NCT04218331

ACTIVE NOT RECRUITING Phase 2 56 participants

Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder

Southwest Autism Research & Resource Center

NCT02839915

ACTIVE NOT RECRUITING NA 55 participants

Testing a Family Service Navigator Program for Low-resourced Families of Young Children with Autism Spectrum Disorder

Vanderbilt University

NCT05099705

ACTIVE NOT RECRUITING Phase 2 55 participants

Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders

Arizona State University

NCT03408886

ACTIVE NOT RECRUITING Phase 2 50 participants

MTT for Children With ASD Who Have Gastrointestinal Disorders

Arizona State University

NCT04182633

ACTIVE NOT RECRUITING Phase 2 48 participants

Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism

Rutgers, The State University of New Jersey

NCT02677051

ACTIVE NOT RECRUITING Phase 2 42 participants

Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism

University of California, San Diego

NCT04517799

ACTIVE NOT RECRUITING Phase 2 40 participants

Pilot Trial of Pregnenolone in Autism

Stanford University

NCT02627508

ACTIVE NOT RECRUITING NA 30 participants

Melatonin and Sleep Spindles in Autism

Massachusetts General Hospital

NCT05716906

ACTIVE NOT RECRUITING NA 24 participants

Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder

Children's Hospital Medical Center, Cincinnati

NCT06670040

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 37
Phase 3 2
Phase 4 2

Named interventions

Most-linked intervention names on Autism Spectrum Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
18 trials
Placebo Other
4 trials
Propranolol Drug
3 trials
SENSE Theatre Behavioral
2 trials
Program for the Education and Enrichment of Relational Skills Behavioral
2 trials
Surviving and Thriving in the Real World Behavioral
2 trials
JASPER Behavioral
2 trials
Cognilum TM: Light Treatment Condition Device
2 trials

US sites by state

Facility locations filed on Autism Spectrum Disorder trials. A trial with sites in several states counts in each.

California 54 trials
New York 30 trials
Ohio 23 trials
Pennsylvania 19 trials
Massachusetts 19 trials
Arizona 17 trials
Texas 16 trials
Maryland 15 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Autism Spectrum Disorder page

225 registered trials, 112 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 112 Autism Spectrum Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Stanford University sponsors the most Autism Spectrum Disorder trials on record, review their full trial history before evaluating a specific study. See Stanford University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Autism Spectrum Disorder condition card totals 225 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.