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ClinicalTrials.gov 112 recruiting now official registry

Autism Spectrum Disorder clinical trials

112 of 225 indexed Autism Spectrum Disorder trials are currently recruiting.

225 US clinical trials · 112 currently recruiting

Autism Spectrum Disorder is the subject of 225 registered US clinical trials on ClinicalTrials.gov, 112 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 19 of these trials.

The research picture

Autism Spectrum Disorder has 225 registered US clinical trials, 112 of them open to new participants right now, about 50% of the total.

112
recruiting participants now
50%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
19
top sponsor: Stanford University
Phase 112Phase 237Phase 32Phase 42

Active & Recent Trials

225 total, page 4 of 5

ACTIVE NOT RECRUITING NA 15 participants

Adapting BA for Minimally Verbal Autistic Adults

Rutgers, The State University of New Jersey

NCT06064422

COMPLETED NA 541 participants

A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism

Stanford University

NCT04739982

COMPLETED 399 participants

Autism Biomarker Consortium for Clinical Trials

Yale University

NCT02996669

COMPLETED 322 participants

Exome Sequencing in Autistic Spectrum Disorder

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01059201

COMPLETED 304 participants

Improving Autism Screening With Brain-Related miRNA

Milton S. Hershey Medical Center

NCT02712853

COMPLETED NA 237 participants

Partnering With Autistic Adults to Improve Healthcare

Oregon Health and Science University

NCT01579669

COMPLETED 186 participants

Study to Assess the Janssen Autism Knowledge Engine in Participants With Autism Spectrum Disorder and in a Normally Developing Cohort

Janssen Research & Development

NCT02668991

COMPLETED Phase 2 180 participants

Cord Blood Infusion for Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT02847182

COMPLETED NA 156 participants

Mind the Gap (AIR-B3)

Health Resources and Services Administration (HRSA)

NCT03711799

COMPLETED NA 155 participants

A Bicycle Training Intervention

University of Michigan

NCT02046889

COMPLETED NA 152 participants

Comparing Behavioral Assessments Using Telehealth for Children With Autism

Matthew J O'Brien, PhD, BCBA-D

NCT02456298

COMPLETED NA 144 participants

Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism

Vanderbilt University Medical Center

NCT03847337

COMPLETED Phase 1 144 participants

A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)

Hoffmann-La Roche

NCT03611075

COMPLETED Phase 2 137 participants

hCT-MSC in Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT04089579

COMPLETED NA 136 participants

SENSE Theatre Intervention for Children With Autism Spectrum Disorder (ASD)

Vanderbilt University

NCT02276534

COMPLETED NA 132 participants

An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD

University of South Florida

NCT05194345

COMPLETED NA 118 participants

Intensive Intervention for Toddlers With Autism (EARLY STEPS)

University of California, Davis

NCT00698997

COMPLETED NA 112 participants

Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism

Richard Solomon MD

NCT01768806

COMPLETED NA 97 participants

Efficacy of IMPACT in Infant Siblings of Children With ASD

Vanderbilt University

NCT03274622

COMPLETED 96 participants

Pediatric Patients With Metabolic or Other Genetic Disorders

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT02769949

COMPLETED NA 91 participants

Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder

The Cleveland Clinic

NCT03668873

COMPLETED NA 91 participants

Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)

University of Washington

NCT05425277

COMPLETED NA 87 participants

Intervention Effects of Intensity and Delivery Style for Toddlers With Autism

University of California, Davis

NCT02272192

COMPLETED NA 86 participants

Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

University of Pittsburgh

NCT03170453

COMPLETED NA 75 participants

Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services

San Diego State University

NCT04295512

COMPLETED NA 73 participants

Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder

Children's Hospital Medical Center, Cincinnati

NCT03984487

COMPLETED NA 72 participants

Enhancing Social Competence in Adults With Autism

Vanderbilt University Medical Center

NCT04349644

COMPLETED NA 72 participants

Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders

University of North Carolina, Chapel Hill

NCT03388294

COMPLETED Early Phase 1 69 participants

Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response

University of Missouri-Columbia

NCT02871349

COMPLETED Phase 2 68 participants

Specifying and Treating Anxiety in Autism Research

University of California, Davis

NCT03279471

COMPLETED NA 61 participants

Examining an Adaptive Telehealth Intervention

Rush University Medical Center

NCT03840642

COMPLETED NA 60 participants

Pediatric Early Autism Recognition System: PEARS

University of Michigan

NCT05153551

COMPLETED Phase 2 60 participants

Intranasal Oxytocin for the Treatment of Children and Adolescents With Autism Spectrum Disorders (ASD)

Holland Bloorview Kids Rehabilitation Hospital

NCT01908205

COMPLETED NA 58 participants

Daily Living Skills Intervention for 9th and 10th Graders With Autism Spectrum Disorders

Children's Hospital Medical Center, Cincinnati

NCT03984513

COMPLETED Phase 2 58 participants

A Trial of Sertraline in Young Children With Autism Spectrum Disorder

Randi J. Hagerman, MD

NCT02385799

COMPLETED Phase 2 58 participants

A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder

Yamo Pharmaceuticals

NCT05067582

COMPLETED NA 50 participants

STEPS: Stepped Transition in Education Program for Students With ASD

Virginia Polytechnic Institute and State University

NCT02468505

COMPLETED 50 participants

ABC-CT Pre-School Feasibility Study

Yale University

NCT06413316

COMPLETED NA 48 participants

Effect of a 9-Month Internship Intervention for Military Dependents With ASD

Virginia Commonwealth University

NCT04001790

COMPLETED NA 44 participants

Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders

University of Pennsylvania

NCT04788537

COMPLETED NA 41 participants

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Northeastern University

NCT06332144

COMPLETED Early Phase 1 40 participants

Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD

Children's Hospital Medical Center, Cincinnati

NCT02874690

COMPLETED NA 40 participants

Robot-Mediated Intervention for Children With Autism Spectrum Disorders

Hugo W. Moser Research Institute at Kennedy Krieger

NCT02617342

COMPLETED 40 participants

Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings

University of Washington

NCT04199533

COMPLETED NA 40 participants

A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders

University of Nebraska

NCT03730194

COMPLETED 37 participants

Early Detection of Autism Spectrum Disorder in Children

St. Louis University

NCT01646866

COMPLETED NA 35 participants

Pediatric Aquatic Occupational Therapy for Children With Sensory Processing Challenges

Kristen Pataki

NCT06484946

COMPLETED 34 participants

Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene

Children's Hospital Medical Center, Cincinnati

NCT03892798

COMPLETED NA 31 participants

A Pilot Study to Characterize the Household Impact of Locating Devices for Children With ASD Who Wander

Northwell Health

NCT03814902

COMPLETED NA 30 participants

Training Attention and Eye Movement in ASD

University of California, San Diego

NCT02403817

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 37
Phase 3 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Autism Spectrum Disorder Trial Landscape

225 indexed Autism Spectrum Disorder studies · 112 recruiting (50%).

Phase mix: 4 late (III/IV) vs 49 early (I/II).

Top sponsor: Stanford University (19 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Autism Spectrum Disorder?

PlainTrial tracks 225 US clinical trials for Autism Spectrum Disorder, of which 112 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Autism Spectrum Disorder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.