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ClinicalTrials.gov 112 recruiting now early-phase tilt #41 of 28,707 conditions

Autism Spectrum Disorder: early-phase trial registry

112 of 225 indexed Autism Spectrum Disorder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #41 of 28,707 conditions by registered trial count.

225 US clinical trials · 112 currently recruiting · #41 of 28,707 conditions by registered trial count

Autism Spectrum Disorder: 225 US clinical trials tracked, 112 recruiting.

Autism Spectrum Disorder is the subject of 225 registered US clinical trials on ClinicalTrials.gov, 112 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 19 of these trials.

Enrollment posture brief

Registry condition autism-spectrum-disorder

OPEN 112 | RECR 50% | LATE 4 | EARLY 49 | RANK #41 | SPON 19

Nearest open-share peer: Alzheimer Disease (50% recruiting · 312 trials)

Autism Spectrum Disorder (th…50%Mild Cognitive Impairment48.5%Sickle Cell Disease44.4%Coronary Artery Disease25.9%Diabetes Mellitus23.3%
Open-enrollment share among volume-matched conditions near Autism Spectrum Disorder

Autism Spectrum Disorder lists 112 open slots (50% of 225 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Autism Spectrum Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Autism Spectrum Disorder is recruiting above its size-band peers.

    112 of 225 indexed trials (49.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Autism Spectrum Disorder trials is spread across many organizations.

    Stanford University accounts for 19 of 225 trials (8.4%). 113 distinct sponsors appear on at least one study for this condition label.

  3. Most Autism Spectrum Disorder trials plan to enrol fewer than 100 people.

    Median target enrolment is 67 among the 225 trials that report a genuine target (sentinel values excluded). 147 of those (65.3%) plan for fewer than 100 participants.

  4. Autism Spectrum Disorder research is mostly interventional.

    195 interventional and 30 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 237Phase 32Phase 42

Open and recent trials

225 total, page 4 of 5

ACTIVE NOT RECRUITING NA 15 participants

Adapting BA for Minimally Verbal Autistic Adults

Rutgers, The State University of New Jersey

NCT06064422

COMPLETED NA 541 participants

A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism

Stanford University

NCT04739982

COMPLETED 399 participants

Autism Biomarker Consortium for Clinical Trials

Yale University

NCT02996669

COMPLETED 322 participants

Exome Sequencing in Autistic Spectrum Disorder

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01059201

COMPLETED 304 participants

Improving Autism Screening With Brain-Related miRNA

Milton S. Hershey Medical Center

NCT02712853

COMPLETED NA 237 participants

Partnering With Autistic Adults to Improve Healthcare

Oregon Health and Science University

NCT01579669

COMPLETED 186 participants

Study to Assess the Janssen Autism Knowledge Engine in Participants With Autism Spectrum Disorder and in a Normally Developing Cohort

Janssen Research & Development

NCT02668991

COMPLETED Phase 2 180 participants

Cord Blood Infusion for Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT02847182

COMPLETED NA 156 participants

Mind the Gap (AIR-B3)

Health Resources and Services Administration (HRSA)

NCT03711799

COMPLETED NA 155 participants

A Bicycle Training Intervention

University of Michigan

NCT02046889

COMPLETED NA 152 participants

Comparing Behavioral Assessments Using Telehealth for Children With Autism

Matthew J O'Brien, PhD, BCBA-D

NCT02456298

COMPLETED NA 144 participants

Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism

Vanderbilt University Medical Center

NCT03847337

COMPLETED Phase 1 144 participants

A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)

Hoffmann-La Roche

NCT03611075

COMPLETED Phase 2 137 participants

hCT-MSC in Children With Autism Spectrum Disorder

Joanne Kurtzberg, MD

NCT04089579

COMPLETED NA 136 participants

SENSE Theatre Intervention for Children With Autism Spectrum Disorder (ASD)

Vanderbilt University

NCT02276534

COMPLETED NA 132 participants

An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD

University of South Florida

NCT05194345

COMPLETED NA 118 participants

Intensive Intervention for Toddlers With Autism (EARLY STEPS)

University of California, Davis

NCT00698997

COMPLETED NA 112 participants

Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism

Richard Solomon MD

NCT01768806

COMPLETED NA 97 participants

Efficacy of IMPACT in Infant Siblings of Children With ASD

Vanderbilt University

NCT03274622

COMPLETED 96 participants

Pediatric Patients With Metabolic or Other Genetic Disorders

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT02769949

COMPLETED NA 91 participants

Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder

The Cleveland Clinic

NCT03668873

COMPLETED NA 91 participants

Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)

University of Washington

NCT05425277

COMPLETED NA 87 participants

Intervention Effects of Intensity and Delivery Style for Toddlers With Autism

University of California, Davis

NCT02272192

COMPLETED NA 86 participants

Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

University of Pittsburgh

NCT03170453

COMPLETED NA 75 participants

Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services

San Diego State University

NCT04295512

COMPLETED NA 73 participants

Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder

Children's Hospital Medical Center, Cincinnati

NCT03984487

COMPLETED NA 72 participants

Enhancing Social Competence in Adults With Autism

Vanderbilt University Medical Center

NCT04349644

COMPLETED NA 72 participants

Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders

University of North Carolina, Chapel Hill

NCT03388294

COMPLETED Early Phase 1 69 participants

Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response

University of Missouri-Columbia

NCT02871349

COMPLETED Phase 2 68 participants

Specifying and Treating Anxiety in Autism Research

University of California, Davis

NCT03279471

COMPLETED NA 61 participants

Examining an Adaptive Telehealth Intervention

Rush University Medical Center

NCT03840642

COMPLETED NA 60 participants

Pediatric Early Autism Recognition System: PEARS

University of Michigan

NCT05153551

COMPLETED Phase 2 60 participants

Intranasal Oxytocin for the Treatment of Children and Adolescents With Autism Spectrum Disorders (ASD)

Holland Bloorview Kids Rehabilitation Hospital

NCT01908205

COMPLETED NA 58 participants

Daily Living Skills Intervention for 9th and 10th Graders With Autism Spectrum Disorders

Children's Hospital Medical Center, Cincinnati

NCT03984513

COMPLETED Phase 2 58 participants

A Trial of Sertraline in Young Children With Autism Spectrum Disorder

Randi J. Hagerman, MD

NCT02385799

COMPLETED Phase 2 58 participants

A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder

Yamo Pharmaceuticals

NCT05067582

COMPLETED NA 50 participants

STEPS: Stepped Transition in Education Program for Students With ASD

Virginia Polytechnic Institute and State University

NCT02468505

COMPLETED 50 participants

ABC-CT Pre-School Feasibility Study

Yale University

NCT06413316

COMPLETED NA 48 participants

Effect of a 9-Month Internship Intervention for Military Dependents With ASD

Virginia Commonwealth University

NCT04001790

COMPLETED NA 44 participants

Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders

University of Pennsylvania

NCT04788537

COMPLETED NA 41 participants

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Northeastern University

NCT06332144

COMPLETED Early Phase 1 40 participants

Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD

Children's Hospital Medical Center, Cincinnati

NCT02874690

COMPLETED NA 40 participants

Robot-Mediated Intervention for Children With Autism Spectrum Disorders

Hugo W. Moser Research Institute at Kennedy Krieger

NCT02617342

COMPLETED 40 participants

Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings

University of Washington

NCT04199533

COMPLETED NA 40 participants

A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders

University of Nebraska

NCT03730194

COMPLETED 37 participants

Early Detection of Autism Spectrum Disorder in Children

St. Louis University

NCT01646866

COMPLETED NA 35 participants

Pediatric Aquatic Occupational Therapy for Children With Sensory Processing Challenges

Kristen Pataki

NCT06484946

COMPLETED 34 participants

Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene

Children's Hospital Medical Center, Cincinnati

NCT03892798

COMPLETED NA 31 participants

A Pilot Study to Characterize the Household Impact of Locating Devices for Children With ASD Who Wander

Northwell Health

NCT03814902

COMPLETED NA 30 participants

Training Attention and Eye Movement in ASD

University of California, San Diego

NCT02403817

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 37
Phase 3 2
Phase 4 2

Named interventions

Most-linked intervention names on Autism Spectrum Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
18 trials
Placebo Other
4 trials
Propranolol Drug
3 trials
SENSE Theatre Behavioral
2 trials
Program for the Education and Enrichment of Relational Skills Behavioral
2 trials
Surviving and Thriving in the Real World Behavioral
2 trials
JASPER Behavioral
2 trials
Cognilum TM: Light Treatment Condition Device
2 trials

US sites by state

Facility locations filed on Autism Spectrum Disorder trials. A trial with sites in several states counts in each.

California 54 trials
New York 30 trials
Ohio 23 trials
Pennsylvania 19 trials
Massachusetts 19 trials
Arizona 17 trials
Texas 16 trials
Maryland 15 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Autism Spectrum Disorder page

225 registered trials, 112 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 112 Autism Spectrum Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Stanford University sponsors the most Autism Spectrum Disorder trials on record, review their full trial history before evaluating a specific study. See Stanford University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Autism Spectrum Disorder condition card totals 225 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.