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NCT04218331 · ClinicalTrials.gov registry record · NA
Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)
A NA study of Autism Spectrum Disorder, sponsored by University of California, Los Angeles.
- Active
- Registry status
- NA
- Development phase
- 56
- Enrollment target
- 2
- Study locations
NCT04218331: Active NA study of Autism Spectrum Disorder, sponsored by University of California, Los Angeles.
NCT04218331 is a NA study of Autism Spectrum Disorder that is active but no longer recruiting, run by University of California, Los Angeles. The registered enrollment target is 56 participants, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (59% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04218331, a NA study of Autism Spectrum Disorder, is active but no longer recruiting, sponsored by University of California, Los Angeles.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
- 2
- Study locations
Study Summary
In this project, the investigator will test the effect of augmenting an evidence based joint attention intervention (JASPER) with a motor-sound system intervention (PROMPT) compared to JASPER only on speech and language outcomes. The investigator will model change over a year to determine the percentage of children who cross the hurdle from single words to word combinations by Kindergarten. The proposed research will foster the understanding of the mechanisms underlying speech heterogeneity in ASD, thereby ultimately contributing to the development of more personalized, efficacious interventions. Upon qualification to the study (after entry assessments), the child will be randomized to receive JASPER alone (play-based intervention) or JASPER plus PROMPT (both play-based and speech-based interventions). The active intervention will last for 12 weeks, 60 minute sessions twice a week. There are assessments scheduled at entry (6.5 hours), end of study (exit-2.5 hours), 3 month follow up (2 hours), and when the child turns 6 years of age (2 hours). The total time commitment per participant is 37 hours.
Primary Outcome
The ELSA is comprised of a series of semi-structured activities including: play-based interactive activities centered around a nature walk (falling leaves; planting an acorn, finding animals; making and eating S'mores); conversational chat and clean up; crafts (art project); games (bean bag toss); and an optional video narration (Pixar short movies, presented to the participant on a tablet). The activities are appropriate for the age range of this study (4 to 7 years). The more words the child
Conditions Studied
Interventions
- BEHAVIORAL JASPER
- BEHAVIORAL PROMPT
Study Locations (2)
California
- UCLA Semel Institute - Los Angeles
- UCLA - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2021-04-29 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What the registry record for NCT04218331 still lists
NCT04218331 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (59% lower).
The record links to 1 condition, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 2 interventions - of which JASPER is the first listed.
NCT04218331 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04218331 about?
NCT04218331 is a clinical study titled "Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)". In this project, the investigator will test the effect of augmenting an evidence based joint attention intervention (JASPER) with a motor-sound system intervention (PROMPT) compared to JASPER only on speech and language outcomes. The investigator will model change over a year to determine the percen...
What is the current status of trial NCT04218331?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 56 participants. The study started on 2021-04-29. Estimated completion is 2026-08-31.
What conditions does trial NCT04218331 study?
This clinical trial studies the following conditions: Autism Spectrum Disorder.
What interventions are being tested in trial NCT04218331?
The interventions under investigation include: JASPER (BEHAVIORAL), PROMPT (BEHAVIORAL).
Who is sponsoring clinical trial NCT04218331?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04218331 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04218331's enrollment target sits among peer trials
56 134th of 224 higher than 89 of 224 other Autism Spectrum Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autism Spectrum Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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