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Atrial Fibrillation: later-stage trial registry
60 of 204 indexed Atrial Fibrillation trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #46 of 28,707 conditions by registered trial count.
204 US clinical trials · 60 currently recruiting · #46 of 28,707 conditions by registered trial count
Atrial Fibrillation: 204 US clinical trials tracked, 60 recruiting.
Atrial Fibrillation is the subject of 204 registered US clinical trials on ClinicalTrials.gov, 60 of them currently open to new participants. 45 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is The Cleveland Clinic, running 9 of these trials.
Enrollment posture brief
Registry condition atrial-fibrillation
OPEN 60 | RECR 29% | LATE 45 | EARLY 19 | RANK #46 | SPON 9
Volume-matched condition peers
Nearest open-share peer: Addiction (29% recruiting · 17 trials)
Atrial Fibrillation lists 60 open slots (29% of 204 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Atrial Fibrillation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Atrial Fibrillation is recruiting below its size-band peers.
60 of 204 indexed trials (29.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Atrial Fibrillation trials is spread across many organizations.
The Cleveland Clinic accounts for 9 of 204 trials (4.4%). 109 distinct sponsors appear on at least one study for this condition label.
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Typical Atrial Fibrillation enrolment sits around 200 participants.
Median target enrolment is 200 among the 203 trials that report a genuine target (sentinel values excluded). 59 of those (29.1%) plan for fewer than 100 participants.
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Atrial Fibrillation splits between interventional and observational designs.
137 interventional and 67 observational studies make up this index (67.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
204 total, page 3 of 5
A Trial With Dronedarone to Prevent Hospitalization or Death in Patients With Atrial Fibrillation
Sanofi
NCT00174785
Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)
Boehringer Ingelheim
NCT02164864
Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation
Brigham and Women's Hospital
NCT00970489
Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)
Pfizer
NCT02100228
A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation
Boehringer Ingelheim
NCT01493557
Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter
Sanofi
NCT00233441
Solutions for Atrial Fibrillation Edvocacy (SAFE)
American Pharmacists Association Foundation
NCT05067114
Withings ECG-Monitor Study
Withings
NCT05316337
American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm
Sanofi
NCT00259376
EHR-Embedded Decision Support to Prevent Stroke in Patients With AF
University of Cincinnati
NCT04099485
Electrocardiogram Clinical Validation Study
Apple
NCT03492554
Understanding and Improving Anticoagulation Dosing for Patients With Atrial Fibrillation
Duke University
NCT03719144
LEAVE Safe With DOACs
University of Massachusetts, Worcester
NCT04068727
Clinical Trial Comparing Devices Used for Cardioversion of Atrial Fibrillation
Inova Health Care Services
NCT05992623
Atrial Fibrillation/Flutter Outcome Risk Determination
Vanderbilt University
NCT01138644
Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Sanofi
NCT00489736
AMBULATE VASCADE MVP Same Day Discharge Retrospective Registry
Cardiva Medical
NCT04538781
Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)
Vanderbilt University
NCT00141778
Sensing Atrial High Rate Episodes With Implantable Cardioverter-Defibrillators Trial (The SENSE Trial)
Weill Medical College of Cornell University
NCT02186704
Efficacy and Safety of Azimilide for the Treatment of Patients With Atrial Fibrillation
Forest Laboratories
NCT00035477
Effect of Oral and Intravenous Diltiazem Protocol for Emergency Department Atrial Fibrillation
Corewell Health South
NCT05391893
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation.
Forest Laboratories
NCT00035464
Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF
Medtronic Cardiac Ablation Solutions
NCT04198701
Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation
Texas Cardiac Arrhythmia Research Foundation
NCT01660100
WIBOFA - Validation of SCT02 With ECG-App for Detection of AF
Withings
NCT06351761
Phase III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Fibrillation
Advanz Pharma
NCT00468767
Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information
Brigham and Women's Hospital
NCT00401414
DECAAF: Delayed-Enhancement MRI (DE-MRI) Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation
University of Utah
NCT01150214
Influence of Sleep Apnea on Risk of Atrial Fibrillation
The Cleveland Clinic
NCT02576587
Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery
MaineHealth
NCT00953212
Study to Determine the Response and Effectiveness of RSD1235 in Subjects With Atrial Fibrillation or Atrial Flutter
Astellas Pharma
NCT00115791
Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity
Abbott RDx Cardiometabolic
NCT01037270
iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology
Columbia University
NCT02731326
Fish Oil for Reduction of Atrial Fibrillation After Cardiac Surgery
Chirag Sandesara
NCT00446966
Video-based Detection of Atrial Fibrillation
University of Rochester
NCT04267133
A Study Exploring Two Treatment Strategies in Patients With Atrial Fibrillation Who Undergo Catheter Ablation Therapy
Janssen Scientific Affairs
NCT01729871
Eliminate Thromboembolism: Improving Anticoagulation in Non-valvular Atrial Fibrillation Patients
Duke University
NCT02461602
Atrial Fibrillation Screening in Nursing Homes
State University of New York at Buffalo
NCT03860246
STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation
Medtronic Cardiac Ablation Solutions
NCT03118518
Study of RSD1235-SR for the Prevention of Atrial Fibrillation/Atrial Flutter Recurrence
Advanz Pharma
NCT00267930
Management of Gastrointestinal and Urogenital (GI/GU) Bleedings in Atrial Fibrillation Patients Using Pradaxa
Boehringer Ingelheim
NCT02022020
QT Variability Pre and Post Cardioversion
Vanderbilt University
NCT00885391
A Genomic Approach to Warfarin Dose Prescription in Admixed Caribbean Hispanics
University of Puerto Ri
NCT02345356
Evaluating the Effectiveness of Fish Oil Supplements at Reducing the Recurrence of Atrial Fibrillation
Vanderbilt University
NCT00552084
STOP Persistent AF
Medtronic Cardiac Ablation Solutions
NCT03012841
Effect of Amiodarone on the Procedure Outcome in Long-standing Persistent Atrial Fibrillation Undergoing Pulmonary Vein Antral Isolation
Texas Cardiac Arrhythmia Research Foundation
NCT01173809
Early Detection and Treatment of Esophageal Injury After Catheter Ablation for Atrial Fibrillation
University of Oklahoma
NCT00584922
Safety and Efficacy of CryoCor™ Cryoablation for PAF
Boston Scientific Corporation
NCT00231296
Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine
Texas Cardiac Arrhythmia Research Foundation
NCT01391091
Study Watch Atrial Fibrillation (AF) Detection Investigation
Verily Life Sciences
NCT04074434
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 12 |
| Phase 3 | 26 |
| Phase 4 | 19 |
Top Sponsors
Named interventions
Most-linked intervention names on Atrial Fibrillation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Atrial Fibrillation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Atrial Fibrillation page
204 registered trials, 60 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 60 Atrial Fibrillation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- The Cleveland Clinic sponsors the most Atrial Fibrillation trials on record, review their full trial history before evaluating a specific study. See The Cleveland Clinic's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atrial Fibrillation condition card totals 204 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.