Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00468767 · ClinicalTrials.gov registry record · Phase 3

Phase III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Fibrillation

A Phase 3 study of Atrial Fibrillation, sponsored by Advanz Pharma.

Completed
Registry status
Phase 3
Development phase
356
Enrollment target
20
Study locations

NCT00468767: Completed Phase 3 study of Atrial Fibrillation, sponsored by Advanz Pharma.

NCT00468767 is a Phase 3 study of Atrial Fibrillation that has completed, run by Advanz Pharma. The registered enrollment target is 356 participants, below the 2,995-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (88% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00468767, a Phase 3 study of Atrial Fibrillation, has completed, sponsored by Advanz Pharma.

COMPLETED
Registry status
Phase 3
Development phase
356 participants
Enrollment target
20
Study locations

Study Summary

This study is being conducted to demonstrate the effectiveness of RSD1235 in the conversion of atrial fibrillation to sinus rhythm.

Conditions Studied

Interventions

  • DRUG Vernakalant Injection 20 mg/mL

Study Locations (20)

Alberta

  • Heart Health Institute, Rockyview General Hospital - Calgary
  • University of Calgary - Calgary
  • University of Alberta Hospital - Edmonton

Ontario

  • Hamilton Health Sciences, Hamilton General Hospital - Hamilton
  • Ottawa Hospitals (Civic & General) - Ottawa
  • Sunnybrook Health Sciences Centre, Emergency Medicine Research Program - Toronto

California

  • University of California - Los Angeles
  • Regional Cardiology Associates - Sacramento

Florida

  • Florida Heart Institute - Orlando
  • James Haley VA Hospital - Tampa

Virginia

  • Medical College of Virginia - Richmond
  • McGuire VA Medical Center - Richmond

Quebec

  • Institut de Cardiologie de Montreal - Montreal
  • Hopital Notre-Dame du CHUM - Montreal

Massachusetts

  • Cardiac Arrhythmia Service, Massachusetts General Hospital - Boston

Michigan

  • Thoracic and Cardiovascular Institute - Lansing

Trial Details

FieldValue
Enrollment Target 356 participants
Start Date 2003-08
Est. Completion 2004-11
Phase Phase 3
Advanz Pharma

4 total trials

What the finished NCT00468767 record still lists

NCT00468767 is an interventional study that assigns participants to a tested intervention. The registered 356 participants enrollment target is mid-sized for trials with a published cap, below the 2,995-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (88% lower).

The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 1 intervention - of which Vernakalant Injection 20 mg/mL is the first listed.

NCT00468767 names 20 study sites across 12 states, led by Alberta, Ontario, California.

Frequently Asked Questions

What is clinical trial NCT00468767 about?

NCT00468767 is a clinical study titled "Phase III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Fibrillation". This study is being conducted to demonstrate the effectiveness of RSD1235 in the conversion of atrial fibrillation to sinus rhythm.

What is the current status of trial NCT00468767?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 356 participants. The study started on 2003-08. Estimated completion is 2004-11.

What conditions does trial NCT00468767 study?

This clinical trial studies the following conditions: Atrial Fibrillation.

What interventions are being tested in trial NCT00468767?

The interventions under investigation include: Vernakalant Injection 20 mg/mL (DRUG).

Who is sponsoring clinical trial NCT00468767?

This trial is sponsored by Advanz Pharma, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00468767 being conducted?

This trial has 20 study locations across California, Florida, Massachusetts, Michigan, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Atrial Fibrillation

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00468767's enrollment target sits among peer trials

356 76th of 202 higher than 127 of 202 other Atrial Fibrillation trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Atrial Fibrillation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06077838 · 356 participants · NA

    RELAXaHEAD for Headache Patients (Phase III)

  • NCT06293469 · 356 participants · NA

    Accelerated Flap Coverage in Severe Lower Extremity Trauma

  • NCT06958328 · 356 participants · Phase 3

    Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

  • NCT06960993 · 356 participants · NA

    Mosaic Trial for Stem Cell Transplant Recipients

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00468767, the US trial registry maintained by the National Library of Medicine. NCT00468767 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.