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NCT04565041 · ClinicalTrials.gov registry record · NA

Social Support and Enhanced Fear Extinction

A NA study of Anxiety and Fear, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
100
Enrollment target
1
Study location

NCT04565041: Recruiting NA study of Anxiety and Fear, sponsored by University of California, Los Angeles.

NCT04565041 is a NA study of Anxiety and Fear that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 100 participants, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04565041, a NA study of Anxiety and Fear, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

University of California, Los Angeles researchers will recruit healthy participants and anxious participants (those diagnosed with social anxiety disorder) age 18-55 years old to participate in a study examining whether the ability of social support figure reminders to enhance the extinction of fear in healthy participants extends to those with anxiety disorders. After being recruited from the UCLA community (healthy participants, n = 50) or referred by treatment providers at the Anxiety and Depression Research Center at UCLA (anxious participants, n = 50) and undergoing a telephone screening and in-person screening, 100 participants will be enrolled in the study, with an expected recruited 150 to reach this number. During the experiment, all participants will undergo the same procedures: undergoing a fear extinction procedure in which threatening cues--cues that predict electric shock--will be paired with either an image of a social support figure (provided by participants) or an image of a smiling stranger. These pairings will be presented repeatedly in the absence of shock in order for fear extinction to occur. Participants will return for a follow-up test to determine if fear extinction was successful.

Primary Outcome

presence of fear response as indicated by significantly higher galvanic skin response (GSR: an index of peripheral stress responding) to a previously learned fearful image (CS+) compared to a baseline comparator (CS-: never learned to be fearful).

Conditions Studied

Interventions

  • BEHAVIORAL Social Support

Study Locations (1)

California

  • UCLA Department of Psychology - Los Angeles

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2022-02-01
Est. Completion 2026-07-01
Phase NA

What NCT04565041 shows while recruiting

NCT04565041 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (77% lower).

The record links to 2 conditions, with Anxiety appearing as the primary indexed condition, and to 1 intervention - of which Social Support is the first listed.

NCT04565041 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04565041 about?

NCT04565041 is a clinical study titled "Social Support and Enhanced Fear Extinction". University of California, Los Angeles researchers will recruit healthy participants and anxious participants (those diagnosed with social anxiety disorder) age 18-55 years old to participate in a study examining whether the ability of social support figure reminders to enhance the extinction of fear...

What is the current status of trial NCT04565041?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2022-02-01. Estimated completion is 2026-07-01.

What conditions does trial NCT04565041 study?

This clinical trial studies the following conditions: Anxiety, Fear.

What interventions are being tested in trial NCT04565041?

The interventions under investigation include: Social Support (BEHAVIORAL).

Who is sponsoring clinical trial NCT04565041?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04565041 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anxiety

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04565041's enrollment target sits among peer trials

100 162nd of 364 higher than 188 of 364 other Anxiety trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anxiety trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04565041, the US trial registry maintained by the National Library of Medicine. NCT04565041 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.