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Anterior Cruciate Ligament Reconstruction: full-pipeline trial registry
7 of 12 indexed Anterior Cruciate Ligament Reconstruction trials are currently recruiting.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 7 currently recruiting · #1,429 of 28,707 conditions by registered trial count
Anterior Cruciate Ligament Reconstruction: 12 US clinical trials tracked, 7 recruiting.
Anterior Cruciate Ligament Reconstruction is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Hospital for Special Surgery, New York, running 2 of these trials.
Enrollment posture brief
Registry condition anterior-cruciate-ligament-reconstruction
OPEN 7 | RECR 58% | LATE 4 | EARLY 3 | RANK #1429 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Bile Duct Cancer (58% recruiting · 12 trials)
Anterior Cruciate Ligament Reconstruction lists 7 open slots (58% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Anterior Cruciate Ligament Reconstruction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Anterior Cruciate Ligament Reconstruction is recruiting above its size-band peers.
7 of 12 indexed trials (58.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Anterior Cruciate Ligament Reconstruction research.
Hospital for Special Surgery, New York accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.
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Typical Anterior Cruciate Ligament Reconstruction enrolment sits around 115 participants.
Median target enrolment is 115 among the 12 trials that report a genuine target (sentinel values excluded). 6 of those (50%) plan for fewer than 100 participants.
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Anterior Cruciate Ligament Reconstruction research is mostly interventional.
11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
Rush University Medical Center
NCT07020312
Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees
Hospital for Special Surgery, New York
NCT06590402
The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
Stanford University
NCT03552705
Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol
University of Connecticut
NCT05968729
Mental Imagery to Improve Quadriceps Strength Post Anterior Cruciate Ligament Reconstruction: a Feasibility Study
Marquette University
NCT06858293
Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction
Yale University
NCT05012982
Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells
The Methodist Hospital Research Institute
NCT06798623
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
University of Pittsburgh
NCT03935750
Pediatric ACL: Understanding Treatment Options
Boston Children's Hospital
NCT02772770
Safety of OMS103HP in Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction
Omeros Corporation
NCT00245271
Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
Hospital for Special Surgery, New York
NCT01586806
Anterior Cruciate Ligament Pain Study
Emory University
NCT02604550
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Anterior Cruciate Ligament Reconstruction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Anterior Cruciate Ligament Reconstruction trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Anterior Cruciate Ligament Reconstruction page
12 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Anterior Cruciate Ligament Reconstruction trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Hospital for Special Surgery, New York sponsors the most Anterior Cruciate Ligament Reconstruction trials on record, review their full trial history before evaluating a specific study. See Hospital for Special Surgery, New York's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anterior Cruciate Ligament Reconstruction condition card totals 12 registered trials; most-linked intervention Bupivacaine with 4 mg of Dexamethasone; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.