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NCT05012982 · ClinicalTrials.gov registry record · NA
Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction
A NA study of Anterior Cruciate Ligament Reconstruction, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 2
- Study locations
NCT05012982: Recruiting NA study of Anterior Cruciate Ligament Reconstruction, sponsored by Yale University.
NCT05012982 is a NA study of Anterior Cruciate Ligament Reconstruction that is actively recruiting participants, run by Yale University. The registered enrollment target is 20 participants, below the 292-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05012982, a NA study of Anterior Cruciate Ligament Reconstruction, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a crossover phase 4 study to evaluate the impact of blood flow restriction on immunometabolism and gene expression in immune cells in individuals undergoing rehabilitation from anterior cruciate ligament reconstruction.
Primary Outcome
Gene expression measured by RNAseq. Because of the nature of RNAseq it is not possible to provide a comprehensive list of gene expression that will be measured; however, genes of particular interest include Slc2a3, Slc2a1, Slc2a4, Slc16a3, PC, Pdha1, Acc1, Fasn.
Conditions Studied
Interventions
- DEVICE AirBand
- DEVICE uninflated AirBand
Study Locations (2)
Connecticut
- Yale New Haven Hospital - Milford
- Gaylord Outpatient Physical Therapy North Haven Clinic - North Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2023-02-16 |
| Est. Completion | 2026-05 |
| Phase | NA |
What NCT05012982 shows while recruiting
NCT05012982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 292-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Anterior Cruciate Ligament Reconstruction appearing as the primary indexed condition, and to 2 interventions - of which AirBand is the first listed.
NCT05012982 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05012982 about?
NCT05012982 is a clinical study titled "Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction". This is a crossover phase 4 study to evaluate the impact of blood flow restriction on immunometabolism and gene expression in immune cells in individuals undergoing rehabilitation from anterior cruciate ligament reconstruction.
What is the current status of trial NCT05012982?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2023-02-16. Estimated completion is 2026-05.
What conditions does trial NCT05012982 study?
This clinical trial studies the following conditions: Anterior Cruciate Ligament Reconstruction.
What interventions are being tested in trial NCT05012982?
The interventions under investigation include: AirBand (DEVICE), uninflated AirBand (DEVICE).
Who is sponsoring clinical trial NCT05012982?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05012982 being conducted?
This trial has 2 study locations across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05012982's enrollment target sits among peer trials
20 10th of 11 higher than 1 of 11 other Anterior Cruciate Ligament Reconstruction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anterior Cruciate Ligament Reconstruction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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