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NCT07020312 · ClinicalTrials.gov registry record · Phase 2
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
A Phase 2 study of Total Knee Arthroplasty and Anterior Cruciate Ligament Reconstruction, sponsored by Rush University Medical Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT07020312 is a Phase 2 study of Total Knee Arthroplasty and Anterior Cruciate Ligament Reconstruction that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 240 participants, below the 287-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (16% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07020312, a Phase 2 study of Total Knee Arthroplasty and Anterior Cruciate Ligament Reconstruction, is actively recruiting participants, sponsored by Rush University Medical Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI). AMI can slow recovery and make physical therapy less effective. This clinical trial is testing whether a special type of brain training-called neurofeedback visualization training-can help improve muscle activation and speed up recovery. In this study, patients will receive standard physical therapy after surgery. Half of them will also use a device that helps them "visualize" exercises while wearing a cap that reads brain signals (EEG). The cap tracks brain activity when patients imagine doing specific movements. A computer then shows a virtual avatar performing the movements, giving feedback in real time-like a video game controlled by the brain. The study includes patients recovering from one of four surgeries: 1. Anterior cruciate ligament reconstruction (ACLR) 2. Total knee arthroplasty (TKA) 3. Total hip arthroplasty (THA) 4. Hip arthroscopy (HA) for femoroacetabular impingement (FAI) The goal is to see if this training improves muscle strength, movement, and daily function more than standard therapy alone. The study will take place at Rush University Medical Center in Chicago and enroll 240 adults, with 60 patients per type of surgery. Each participant will be followed for up to 6 months after surgery and complete strength tests, movement assessments, and questionnaires about their recovery. The hope is that combining brain training with physical therapy will lead to faster, more complete recoveries and improve how patients move after surgery.
Conditions Studied
Interventions
- OTHER Visualization training with neurofeedback
- OTHER Standard post-surgical rehabilitation therapy
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2025-08-14 |
| Est. Completion | 2028-08 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07020312
The ClinicalTrials.gov registry entry for NCT07020312 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 287-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (16% lower). The listed sponsor is Rush University Medical Center, which has 320 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Total Knee Arthroplasty appearing as the primary indexed condition, and to 2 interventions - of which Visualization training with neurofeedback is the first listed.
NCT07020312 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT07020312 about?
NCT07020312 is a clinical study titled "Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery". After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI). AMI can slow recovery and make physical therapy less effective. This clinical trial is testing whether a special type of brai...
What is the current status of trial NCT07020312?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2025-08-14. Estimated completion is 2028-08.
What conditions does trial NCT07020312 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty, Anterior Cruciate Ligament Reconstruction, Hip Arthroscopy, Total Hip Arthroplasty (THA).
What interventions are being tested in trial NCT07020312?
The interventions under investigation include: Visualization training with neurofeedback (OTHER), Standard post-surgical rehabilitation therapy (OTHER).
Who is sponsoring clinical trial NCT07020312?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07020312 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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